Quantitation of erbB-2 gene copy number in breast cancer by an improved polymerase chain reaction (PCR) technique, competitively differential PCR

Breast Cancer Research and Treatment

Volumn 58, Issue 3, 1999, Pages 213-217

  Deng, Guoren ^a,b   Kim, Young S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Breast cancer; Gene amplification; Polymerase chain reaction

Indexed keywords

ACCURACY; ARTICLE; BREAST CANCER; CANCER GENETICS; CONTROLLED STUDY; DNA DETERMINATION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; METHODOLOGY; ONCOGENE NEU; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOUTHERN BLOTTING;

EID: 0033491389     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1006367700783     Document Type: Article

References (6)

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2. 2. Frye RA, Benz CC, Liu E: Detection of amplified oncogenes by differential polymerase chain reaction. Oncogene 4: 1153-1157, 1989
3. 3. Siebert PD, Larrick JW: Competitive PCR. Nature 359: 557-558, 1992
4. 4. Deng G, Yu M, Smith HS: An improved method for competitive PCR for quantitation of gene copy number. Nucleic Acids Res 21: 4848-4849, 1993
5. 5. Kailioniemi O-P, Kallioniemi A, Kurisu W, Thor A, Chen L-C, Smith HS, Waldman FM, Pinkel D, Gray JW: erbB2 amplification in breast cancer analyzed by fluorescence in situ hybridization. Proc Natl Acad Sci USA 89: 5321-5325, 1992
6. 6. Deng G, Yu M, Chen L-C, Moore D, Kurisu W, Kallioniemi A, Waldman FM, Collin C, Smith HS: Amplifications of the oncogene erhB-2 and the chromosome 20q in breast cancer determined by differentially competitive polymerase chain reaction. Breast Cancer Res and Treat 40: 271-281, 1996