An exceedingly mild and efficient CAN mediated method for the deprotection of acetals

Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry

Volumn 38, Issue 11, 1999, Pages 1234-1236

  Nair, Vijay ^a   Nair, Latha G ^a   Balagopal, Lakshmi ^a   Rajan, Roshini ^a  

^a REGIONAL RESEARCH LABORATORY CSIR   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAL DERIVATIVE; AMMONIUM NITRATE; CERIUM;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; OXIDATION; REACTION ANALYSIS;

EID: 0033490996     PISSN: 03764699     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

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23. General experimental procedure. Acetal (1 mmole) was dissolved in 2 mL 10 % methanol. CAN in 8 mL 10 % methanol was added to it dropwise with constant stirring at room temperature. The reaction mixture was diluted with water (10 min. after the addition of CAN) and extracted with dichloromethane. The dichloromethane layer was washed with saturated brine and dehydrated using anhyd. sodium sulphate, filtered and the solvent was evaporated off. The residue on column chromatography using silica-gel (5 % ethyl acetate-hexane mixture) afforded the corresponding aldehyde or ketone.
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