p53 autoantibodies in patients with autoimmune diseases: A quantitative approach

Autoimmunity

Volumn 31, Issue 4, 1999, Pages 229-235

  Kuhn, Hella Monika ^a,d   Kromminga, Arno ^a   Flammann, Heiko T ^a   Frey, Manfred ^b   Layer, Peter ^c   Arndt, Rüdiger ^a  

^a Inst Immunol   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c ISRAELITISCHES KRANKENHAUS   (Germany)

^d IPM   (Germany)

Author keywords

Antibody levels; Autoimmune diseases; p53 autoantibodies

Indexed keywords

AUTOANTIBODY; PROTEIN P53;

ADULT; ALLERGIC VASCULITIS; ANTIBODY BLOOD LEVEL; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CANCER PATIENT; CONTROLLED STUDY; FEMALE; GRAVES DISEASE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; QUANTITATIVE ASSAY; SERUM; SYSTEMIC LUPUS ERYTHEMATOSUS; TUMOR SUPPRESSOR GENE; WEGENER GRANULOMATOSIS;

EID: 0033490522     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939908994068     Document Type: Article

References (26)

1. Fishman, P., Merimsky, O. and Shoenfeld, Y. Autoimmunity and cancer beneficial relationships: A new concept for the production of human monoclonal antibodies. Int. J. Oncol. 1997; 10: 901-904.
2. Mowat, M.R.A. p53 in tumor progression: Life, death, and everything. Adv. Cancer Res. 1998; 74: 25-48.
3. Alvarado-de la Barrera, C., Alcocer-Varela, J., Richaud-Patin, Y., Alarcon-Segovia, D. and Llorente, L. Differential oncogene and TNF-α mRNA expression in bone marrow cells from systemic lupus erythematosus patients. Scand. J. Immunol. 1998; 48: 551-556.
4. Hollstein, M., Sidranskv, D., Vogelstein, B. and Harris, C. p53 mutations in human cancers. Science 1991; 253: 49-53.
5. Schlichtholz, B., Legros, Y., Gillet, D., Gaillard, C., Marty, M., Lane, D., Calvo, F. and Soussi, T. The immune response to p53 in breast cancer patients is directed against immunodominant epitopes unrelated to the mutatioual hot spots. Cancer Res. 1992; 52: 6380-6384.
6. Labrecque, S., Naor, N., Thomson, D. and Matlashewski, G. Analysis of the anti-p53 antibody response in cancer patients. Cancer Res. 1993; 53: 3468-3471.
7. Peyrat, J.-P., Bonneterre, J., Lubin, R., Vanlemmens, L., Fournier, J. and Soussi, T. Prognostic significance of circulating p53 antibodies in patients undergoing surgery for locoregional breast cancer. Lancet 1995; 345: 621-622.
8. Würl, P., Weigmann, F., Meye, A., Fittkau, M., Rose, U., Berger, D., Rath, F.W., Dralle, H. and Taubert, H. Detection of p53 autoantibodies in sera of gastric cancer patients and their prognostic relevance, Scand. J. Gastroenterol. 1997; 32: 1147-1151.
9. Houbiers, J.G.A., van der Burg, S.H., van de Watering, L.M.G., Tollenaar, R.A.E.M., Brandt, A., van de Velde, C.J.H. and Melief, C.J.M. Antibodies against p53 are associated with poor prognosis of colorectal cancer. Br. J. Cancer 1995; 72: 637-641.
10. Ruiz, P.J., Wolkowicz, R., Waisman, A., Hirschberg, D.L,. Carmi, P., Erez, N., Garren, H., Herkel, J., Karpuj, M., Steinman, L., Rotler, V. and Cohen, I.R. Idiotypic immunization induces immunity to mutated p53 and tumor rejection. Nature Medicine 1998; 6: 710-712.
11. Yashar, C.M., Gercel-Taylor, C., Gibb, R.K., Wecks, J.W. and Taylor, D.D. Identification of a unique form ot p53 in human cord blood associated with the development of maternal autoantibodies. Am. J. Reprod. Immunol. 1998; 39: 368-375.
12. Chen, Y.M.A., Chen. S.U., Fu, C.Y., Chen, J.Y. and Osame, M. Antibody reactivities to tumor-suppressor protein p53 and HTLV-I Tof, Rex and Tax in HTLV-I-infected people with differing clinical status. Int. Cancer 1997; 71: 196-202.
13. Marsen, J., Schmiegel, W., Röder, C., Harder, R., Juhl, H., Hanne-Bruhns, D., Kremer, B. and Kalthoff, H., Detection of the anti-p53 antibody response in malignant and benign pancreatic disease. Br. J. Cancer 1994; 70: 1031-1034.
14. Kovacs, B., Patel, A., Hershey, J.N., Dennis, G.J., Kirschfink, M. and Tsokos, G.C. Antibodies against p53 in sera from patients with systemic lupus erythematosus and other rheumatic diseases. Arthritis Rheum. 1997; 40: 980-982.
15. Tan, L.M., Cohen, A.S., Fries, J.F., Masi, A.T., MeShane, D.J., Rothfield, N.F., Sehaller, J.G. Talal, N. and Winchester, R.J. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1982; 25: 1271-1277.
16. Nedbal, W., Frey, M., Willemann, B., Zentgraf, H. and Sczakiel, G. Mechanistic insights into p53-promoted RNA RNA annealing. J. Mol. Biol. 1997; 266: 677-687.
17. Angelopoulou, K., Diamandis, E.P., Sutherland, D.J.A., Kellen, J.A. and Bunting, P.S. Prevalence of serum antibodies against the p53 tumour gene protein in various cancers. Int. J. Cancer 1994; 58: 480-487.
18. Winter, S.F., Minna, J.D., Johnson, B.F., Takahashi, T., Gazdar, A.F. and Carbone, D.P. Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation. Cancer Res. 1992; 52: 4168-4174.
19. Davidoff, A.M., Iglchart, J.D. and Marks, J.R. Immune response to p53 is dependent upon p53 HSP70 complexes in breast cancers, Proc. Natl. Acad. Sci. 1992: 89; 3439-3442.
20. Preudhomme, C., Lubin, R., Lepelley, P., Vanrumbeke, M. and Fenaux, P. Detection of serum anti-p53 antibodies and their correlation with p53 mutations in myclodysplastic syndromes and acute mycloid leukemia. Leukemia 1994; 8: 1589-1591.
21. Wild, C.P., Ridanpää, M., Anttila, S., Lubin, R., Soussi, T., Husgafvel-Fursiainen, K. and Vanino, H. p53 antibodies in the sera of lung cancer patients: comparison with p53 mutation in the tumour tissue. Int. J. Cancer 1995; 64: 176-181.
22. Cawley, H.L., Meltzer, S.J., De Benedetti, V.M.G., Hollstein, M.C., Muchlbauer, K. R., Liang, L., Benett, W.P., Souza, R.F., Greenwald, B.D., Cottrell, J., Salabes, A., Bartsch, H. and Trivers, G. E. Anti-p53 antibodies in patients with Barrett's esophagus or esophageal carcinoma can predate cancer diagnosis. Gastroenterology 1998; 115: 19-27.
23. Hong, X., Hamilton, K.J., Satoh, M., Wang, J. and Reeves, W.H. Initiation of autoimmunity to the p53 tumor suppressor protein by complexes of p53 and SV40 large T antigen. J. Exp. Med. 1994; 179: 1243-1252.
24. Lubin, R., Schlichtholz, B., Teillaud, J.L., Garay, E., Bussel, A., Wild, C.P. and Soussi, I. Serum p53 antibodies as early markers of lung cancer. Nature Med. 1995; 1: 701-702.
25. Trivers, G., Cawley, H.L., De Benedetti, V.M.G., Hollstein, M., Marion, M.J., Benett, W.P., Hoover, M.L., Prives, C.C., Tamburro, C.C. and Harris, C.C. Anti-p53 antibodies in sera of workers occupationally exposed to vinyl chloride. J. Natl. Cancer Inst. 1995; 87: 1400-1407.
26. Trivers, G.E., De Benedetti, V.M.G., Cawley, H.L., Caron, G., Harrington, A.M., Bennett, W.P., Jett, J.R., Colby, T.V., Tazelaar, H., Pairolero, P., Miller, D. and Harris, C.C. Anti-p53 antibodies in sera from patients with chronic obstructive pulmonary disease can predate a diagnosis of cancer. Clin. Cancer Res. 1996; 2: 1767-1775.