Characterisation of the beta-tubulin gene of Cylicocyclus nassatus

International Journal for Parasitology

Volumn 29, Issue 12, 1999, Pages 1941-1947

  Pape, Michaela ^a   Von Samson Himmelstjerna, Georg ^b   Schniede, Thomas ^a  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b BAYER AG   (Germany)

Author keywords

Tubulin gene; Benzimidazole; Cyathostominae; Cylicocyclus nassatus; Drug resistance; Nematode

Indexed keywords

BETA TUBULIN; MESSENGER RNA;

AMINO ACID SEQUENCE; ARTICLE; DNA SEQUENCE; GENE STRUCTURE; GENETIC ANALYSIS; NEMATODE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA, HELMINTH; MOLECULAR SEQUENCE DATA; RNA, MESSENGER; STRONGYLOIDEA; TUBULIN;

EID: 0033486306     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(99)00156-3     Document Type: Article

References (17)

1. Dustin P. Microtubules. New York: Springer, 1984.
2. Lacey E. The role of the cytoskeletal protein, tubulin, in the mode of action and mechanism of drug resistance to benzimidazoles. Int J Parasitol. 18:1988;885-936.
3. Davidse L.C. Benzimidazole fungicides: mechanism of action and biological impact. Annu Rev Phytopathol. 24:1986;43-65.
4. Dawson P.J., Gutteridge W.E., Gull K. A comparison of the interaction of anthelmintic benzimidazoles with tubulin isolated from mammalian tissue and the parasitic nematode Ascaridia galli. Biochem Pharmacol. 33:1984;1069-1074.
5. Cleveland D.W., Sullivan K.F. Molecular biology and genetics of tubulin. Annu Rev Biochem. 54:1985;331-365.
6. Sullivan K.F. Structure and utilization of tubulin isotypes. Annu Rev Cell Biol. 4:1988;687-716.
7. Driscoll M.E., Dean E., Reilly E., Bergholz E., Chalfie M. Genetic and molecular analysis of Caenorhabditis elegans β-tubulin that conveys benzimidazole sensitivity. J Cell Biol. 109:1989;2993-3003.
8. Savage C., Chalfie M. Genetic aspects of microtubule biology in the nematode Caenorhabditis elegans. Cell Motil Cytoskel. 18:1991;159-163.
9. Guenette S., Prichard R.K., Klein R.D., Matlashewski G. Characterization of a β-tubulin gene and β-tubulin gene products of Brugia pahangi. Mol Biochem Parasitol. 44:1991;153-164.
10. Guenette S., Prichard R. K, Matlashewski G. Identification of a novel Brugia pahangi beta-tubulin gene (beta 2) and a 22-nucleotide spliced leader sequence on beta 1-tubulin mRNA. Mol Biochem Parasitol. 50:1992;275-284.
11. Kwa M.S.G., Veenstra J.G., Roos M.H. Molecular characterisation of β-tubulin genes present in benzimidazole-resistant populations of Haemonchus contortus. Mol Biochem Parasitol. 60:1993;133-144.
12. Roos M.H., Kwa M.S.G., Grant W.N. New genetic and practical implications of selection for anthelmintic resistance in parasitic nematodes. Parasitol Today. 11:1995;148-150.
13. Lichtenfels J.R. Helminths of domestic equids. Proc Helminth Soc Wash. 42(Special issue):1975;1-92.
14. Blaxter M., Liu L. Nematode spliced leaders - ubiquity, evolution and utility. Int J Parasitol. 26:1996;1025-1033.
15. Geary T.G., Nulf S.C., Favreau M.A.et al. Three β-tubulin cDNAs from the parasitic nematode Haemonchus contortus. Mol Biochem Parasitol. 50:1991;295-306.
16. Elard L., Comes A.M., Humbert J.F. Sequences of β-tubulin cDNA from benzimidazole-susceptible and -resistant strains of Teladorsagia circumcincta, a nematode parasite of small ruminants. Mol Biochem Parasitol. 79:1996;249-253.
17. Kwa M.S.G., Veenstra J.G., van Dijk M., Roos M.H. β-Tubulin genes from the parasitic nematode Haemonchus contortus modulate drug resistance in Caenorhabditis elegans. J Mol Biol. 246:1995;500-510.