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RRB1 and RRB2 encode maize retinoblastoma-related proteins that interact with a plant D-type cyclin and geminivirus replication protein
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This paper demonstrates that maize Rb protein (ZmRb) abundance is correlated with the state of leaf cell differentiation and that ZmRb interacts in vitro with Arabidopsis CycD cyclins. These interactions depend on the conserved LxCxE amino-terminal motif that is also needed for human D-cyclin interaction with Rb.
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The first report and analysis of a CAK from Arabidopsis, which is not related to the CAK gene of rice (OsR2). Very interestingly, this Arabidopsis CAK does not phosphorylate the CTD of RNA polymerase II, but can activate human CDK2; moreover, Arabidopsis CAK is shown to complement CAK mutants in both budding and fission yeast.
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The OsR2 gene encodes an active CAK that is unrelated to Arabidopsis CAK but similar to the CDK7 subunit of human CAK. Evidence is presented that this protein can phosphorylate both human CDK2 and a rice cdc2a (CDK-a).
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Sun Y.J., Dilkes B.P., Zhang C.S., Dante R.A., Carneiro N.P., Lowe K.S., Jung R., Gordon-Kamm W.J., Larkins B.A. Characterization of maize (Zea mays L.) wee1 and its activity in developing endosperm. Proc Natl Acad Sci USA. 96:1999;4180-4185. This paper represents the first evidence that phosphorylation of CDKs by wee1 kinases is conserved in plants, and provides important evidence for regulatory phosphorylation of plant CDKs. It reinforces the likely significance of cdc25 phosphatases in reversing the inhibitory phosphorylation by wee1 kinases, and allowing cell cycle progression [16,17].
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Cyclin CycD genes are analysed for the first time in the highly synchonisable BY-2 cell system, and two of the genes examined show highest mRNA levels during mitosis. It is unclear whether this is specific to this cell culture or is a general feature not yet revealed in other plant systems. More in keeping with other results is the finding that the genes are switched off in stationary phase cells and are reactivated during cell cycle entry.
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The first analysis of a dicot Rb protein, and the first biochemical indication that cyclin CycD proteins interact with PSTAIRE (cdc2a, CDK-a) CDKs in vivo. The kinase CycD-cdc2a assembled in insect cells is shown to direct phosphorylation of Rb proteins in vitro. Note that no laboratory has yet demonstrated phosphorylation of Rb using kinase immunoprecipitated from plant cells.
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Nakagami H., Sekine M., Murakami H., Shinmyo A. Tobacco retinoblastoma-related protein phosphorylated by a distinct cyclin-dependent kinase complex with Cdc2/cyclin D in vitro. Plant J. 18:1999;243-252. The first analysis of a dicot Rb protein, and the first biochemical indication that cyclin CycD proteins interact with PSTAIRE (cdc2a, CDK-a) CDKs in vivo. The kinase CycD-cdc2a assembled in insect cells is shown to direct phosphorylation of Rb proteins in vitro. Note that no laboratory has yet demonstrated phosphorylation of Rb using kinase immunoprecipitated from plant cells.
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The discovery of a new class of D-type cyclin gene (CycD4) that is related to the CycD2 gene of Arabidopsis and is shown to have a very interesting transitory expression pattern during the development of lateral roots. Like CycD2, this gene is induced when sucrose is re-supplied to starved cells, this induction is concomitant with the increase in mRNA of its potential kinase partner cdc2aAt (CDK-a).
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Cooke R., Meyer Y. Hormonal control of tobacco protoplast nucleic-acid metabolism during in vitro culture. Planta. 152:1981;1-7.
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Planta
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Cooke, R.1
Meyer, Y.2
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41
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0030839266
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The Arabidopsis cks1At protein binds the cyclin-dependent kinases cdc2aAt and cdc2bAt
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De Veylder L., Segers G., Glab N., Casteels P., Van Montagu M., Inzé D. The Arabidopsis cks1At protein binds the cyclin-dependent kinases cdc2aAt and cdc2bAt. FEBS Letts. 412:1997;446-452.
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FEBS Letts
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De Veylder, L.1
Segers, G.2
Glab, N.3
Casteels, P.4
Van Montagu, M.5
Inzé, D.6
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42
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0033082598
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Expression of cks1At in Arabidopsis thaliana indicates a role for the protein in both the mitotic and the endoreduplication cycle
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A detailed analysis by in situ hybridisation of Arabidopsis shoot apices shows that the cell cycle genes cdc2aAt, cdc2bAt and cyclin CycB1;1 are expressed in mitotic cells, whereas the gene encoding the Suc1 homologue cks1At was present in both mitotic and endoreduplicating cells. This paper raises the interesting question of which CDK is regulating endoreduplication.
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Jacqmard A., De Veylder L., Segers G., Engler J.D., Bernier G., Van Montagu M., Inzé D. Expression of cks1At in Arabidopsis thaliana indicates a role for the protein in both the mitotic and the endoreduplication cycle. Planta. 207:1999;496-504. A detailed analysis by in situ hybridisation of Arabidopsis shoot apices shows that the cell cycle genes cdc2aAt, cdc2bAt and cyclin CycB1;1 are expressed in mitotic cells, whereas the gene encoding the Suc1 homologue cks1At was present in both mitotic and endoreduplicating cells. This paper raises the interesting question of which CDK is regulating endoreduplication.
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Planta
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Jacqmard, A.1
De Veylder, L.2
Segers, G.3
Engler, J.D.4
Bernier, G.5
Van Montagu, M.6
Inzé, D.7
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43
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Trends in plant cell cycle research
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Inzé D., Gutiérrez C., Chua N.-H. Trends in plant cell cycle research. Plant Cell. 11:1999;991-994.
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Plant Cell
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Inzé, D.1
Gutiérrez, C.2
Chua, N.-H.3
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44
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A plant cyclin-dependent kinase inhibitor gene
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Wang H., Fowke L.C., Crosby W.L. A plant cyclin-dependent kinase inhibitor gene. Nature. 386:1997;451-452.
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Nature
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Wang, H.1
Fowke, L.C.2
Crosby, W.L.3
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45
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0032142878
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ICK1, a cyclin-dependent protein kinase inhibitor from Arabidopsis thaliana interacts with both cdc2a and CycD3, and its expression is induced by abscisic acid
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The first detailed analysis of a CKI (CDK inhibitor protein) in plants, which is shown to bind both to the CDK (cdc2a) and to the cyclin CycD3 raising the interesting possibility of dual modes of action in inhibiting both assembly and activity of the CDK complex. Interestingly, ICK1 is shown to be induced in the presence of abscisic acid, suggesting that it may be involved in cell cycle arrest in response to this hormone.
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Wang H., Qi Q.G., Schorr P., Cutler A.J., Crosby W.L., Fowke L.C. ICK1, a cyclin-dependent protein kinase inhibitor from Arabidopsis thaliana interacts with both cdc2a and CycD3, and its expression is induced by abscisic acid. Plant J. 15:1998;501-510. The first detailed analysis of a CKI (CDK inhibitor protein) in plants, which is shown to bind both to the CDK (cdc2a) and to the cyclin CycD3 raising the interesting possibility of dual modes of action in inhibiting both assembly and activity of the CDK complex. Interestingly, ICK1 is shown to be induced in the presence of abscisic acid, suggesting that it may be involved in cell cycle arrest in response to this hormone.
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Plant J
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Wang, H.1
Qi, Q.G.2
Schorr, P.3
Cutler, A.J.4
Crosby, W.L.5
Fowke, L.C.6
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46
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The retinoblastoma pathway in plant cell cycle and development
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Gutiérrez C. The retinoblastoma pathway in plant cell cycle and development. Curr Opin Plant Biol. 1:1998;492-497.
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Gutiérrez, C.1
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47
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The cloning of plant E2F, a retinoblastoma-binding protein, reveals unique and conserved features with animal G1/S regulators
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This recent paper describes the cloning and structure of a wheat E2F cDNA and shows that binding of wheat E2F protein to ZmRb1 depends on different residues from those present in animal E2F proteins.
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Ramirez-Parra E., Xie Q., Boniotti M.B., Gutiérrez C. The cloning of plant E2F, a retinoblastoma-binding protein, reveals unique and conserved features with animal G1/S regulators. Nucl Acids Res. 27:1999;3527-3533. This recent paper describes the cloning and structure of a wheat E2F cDNA and shows that binding of wheat E2F protein to ZmRb1 depends on different residues from those present in animal E2F proteins.
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Nucl Acids Res
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Ramirez-Parra, E.1
Xie, Q.2
Boniotti, M.B.3
Gutiérrez, C.4
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48
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Conserved family of WD-40 proteins binds to the retinoblastoma protein in both plants and animals
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Ach R.A., Taranto P., Gruissem W.A. conserved family of WD-40 proteins binds to the retinoblastoma protein in both plants and animals. Plant Cell. 9:1997;1595-1606.
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Plant Cell
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Ach, R.A.1
Taranto, P.2
Gruissem, W.A.3
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49
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Differential expression of a CAK (cdc2-activating kinase)-like protein kinase, cyclins and cdc2 genes from rice during the cell cycle and in response to gibberellin
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Sauter M. Differential expression of a CAK (cdc2-activating kinase)-like protein kinase, cyclins and cdc2 genes from rice during the cell cycle and in response to gibberellin. Plant J. 11:1997;181-190.
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Sauter, M.1
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50
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0041294497
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The cdc2Ms kinase is differently regulated in the cytoplasm and in the nucleus
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Bögre L., Zwerger K., Meskiene I., Binarova P., Csizmadia V., Planck C., Wagner E., Hirt H., Heberle-Bors E. The cdc2Ms kinase is differently regulated in the cytoplasm and in the nucleus. Plant Physiol. 113:1997;841-852.
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Plant Physiol
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Bögre, L.1
Zwerger, K.2
Meskiene, I.3
Binarova, P.4
Csizmadia, V.5
Planck, C.6
Wagner, E.7
Hirt, H.8
Heberle-Bors, E.9
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51
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Conserved and novel regulators of the plant cell cycle
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Doonan J., Fobert P. Conserved and novel regulators of the plant cell cycle. Curr Opin Cell Biol. 9:1997;824-830.
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Doonan, J.1
Fobert, P.2
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52
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2 on cell division in shoot meristems: Differential responses of two natural populations of Dactylis glomerata L
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2 on cell division in shoot meristems: differential responses of two natural populations of Dactylis glomerata L. Plant Cell Envir. 19:1996;775-780.
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Plant Cell Envir
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Kinsman, E.A.1
Lewis, C.2
Davies, M.S.3
Young, J.E.4
Francis, D.5
Thomas, I.D.6
Chorlton, K.H.7
Ougham, H.J.8
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54
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0032144978
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Cellular parameters of the shoot apical meristem in Arabidopsis
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A beautiful analysis of cell proliferation rates within different zones of the Arabidopsis shoot apex in both wild-type and enlarged meristem mutants using confocal sectioning. These results confirm classic models of a small central zone of slowly proliferating cells and provide the techniques to analyse the effect of mutants on cell division patterns in the meristem.
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Laufs P., Grandjean O., Jonak C., Kieu K., Traas J. Cellular parameters of the shoot apical meristem in Arabidopsis. Plant Cell. 10:1998;1375-1389. A beautiful analysis of cell proliferation rates within different zones of the Arabidopsis shoot apex in both wild-type and enlarged meristem mutants using confocal sectioning. These results confirm classic models of a small central zone of slowly proliferating cells and provide the techniques to analyse the effect of mutants on cell division patterns in the meristem.
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(1998)
Plant Cell
, vol.10
, pp. 1375-1389
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Laufs, P.1
Grandjean, O.2
Jonak, C.3
Kieu, K.4
Traas, J.5
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55
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Genetic control of cell division patterns in developing plants
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Meyerowitz E.M. Genetic control of cell division patterns in developing plants. Cell. 88:1997;299-308.
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D. Francis, D. Dudits, & D. Inzé. London: Portland Press
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Traas J., Laufs P. Cell cycle mutants in higher plants: A phenotypical overview. Francis D., Dudits D., Inzé D. Plant Cell Division. 1998;319-336 Portland Press, London.
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Plant Cell Division
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Traas, J.1
Laufs, P.2
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Analysis of cell division and elongation underlying the developmental acceleration of root growth in Arabidopsis thaliana
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Beemster G.T.S., Baskin T.I. Analysis of cell division and elongation underlying the developmental acceleration of root growth in Arabidopsis thaliana. Plant Physiol. 116:1998;1515-1526.
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Plant Physiol
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Beemster, G.T.S.1
Baskin, T.I.2
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