Process improvements in the production of a novel non-xanthine adenosine A1 receptor antagonist. A "one-pot" horner-emmons isomerization reaction

Organic Process Research and Development

Volumn 3, Issue 6, 1999, Pages 394-399

  Zanka, Atsuhiko ^a   Itoh, Norihumi ^a   Kuroda, Satoru ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0033481860     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op990066i     Document Type: Article

References (6)

1. (a) Zanka, A. Org. Process Res. Dev. 1998, 2, 60.
2. (b) Zanka, A.; Hashimoto, N.; Uematsu. R.: Okamoto, T. Org. Process Res. Dev. 1998, 2, 320.
3. (a) Horiai, H.; Kohno, Y.; Minoura, H.; Takeda, M.; Nakano, K.; Hanaoka, K.; Kusunoki, T.; Otsuka, M.; Shimomura, K. Can. J. Physiol. Phannacol. 1994, 72, P17.3.9.
4. (b) Takeda, M.; Kohno, Y.; Esumi, K.; Horiai, H.; Ohtsuka, M.; Shimomura, K.; Imai, M. Jpn. J. Phannacol. 1994, 64, O-376.
5. Kuroda, S.; Akahane, A.; Itani, H.; Nishimura, S.; Durkin, K.; Kinoshita, T.; Tenda, Y:; Sakane, K. Bioorg. Med. Chem. Lett. 1999, 9, 1979.
6. Kuroda, S.; Akahane, A.; Itani, H.; Nishimura, S.; Durkin, K.; Kinoshita, T.; Nakanishi, I.; Sakane, K. Tetrahedron 1999, 55, 10351.