Synthesis of CMI-977, a potent 5-lipoxygenase inhibitor

Organic Process Research and Development

Volumn 3, Issue 1, 1999, Pages 73-76

  Cai, Xiong ^a   Chorghade, Mukund S ^a   Fura, Aberra ^a   Grewal, Gurmit S ^a   Jauregui, Karen A ^a   Lounsbury, Heather A ^a   Scannell, Ralph T ^a   Yeh, C Grace ^a   Young, Michelle A ^a   Yu, Shaoxia ^a   Guo, Liang ^b   Moriarty, Robert M ^b   Penmasta, Raju ^b   Rao, Munagala S ^b   Singhal, Rajesh K ^b   Song, Zhengzhe ^b   Staszewski, James P ^b   Tuladhar, Sudersan M ^b   Yang, Sanmin ^b  

^a CytoMed Inc   (United States)

^b Steroids Ltd   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0033481678     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op980209l     Document Type: Article

References (8)

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2. (a) Carter, G. W.; Young, P. R.; Albert, D. H.; Bouska, J. B.; Dyer, R.; Bell, R.; Summers, J. B.; Brooks, D. W. J. Pharmacol Exp. Ther. 1991, 256, 929.
3. (b) Spector, S. L. Ann. Allergy. Asthma Immunol. 1995, 75, 463-474.
4. (c) Holgate, S. T.; Sampson, A. P. J. Allergy Clin. Immunol. 1996, 98, 1-13.
5. (a) Ravid, U.; Silverstein, R. M.; Smith, L. R. Tetrahedron 1978, 34, 1449-1452.
6. (b) Gringore, O. H.; Rouessac, F. P. Organic Syntheses; Wiley: New York, 1990; Collect. Vol. VII, pp 99-102.
7. Mitsunobu, O. Synthesis 1981, 1.
8. Thompson, A. S.; Tschaen, D. M.; Simpson, P.; McSwine, T. J.; Raemer, R. A.; Verhoeven, T. R.; Shinkai, I. J. Org. Chem. 1992, 57, 7044-7052.