An update on endotoxaemia Part 2: Treatment and the way ahead

Equine Veterinary Education

Volumn 11, Issue 1, 1999, Pages 30-34

  Moore, J N ^a   Barton, Michelle H ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0033477456     PISSN: 09577734     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-3292.1999.tb00915.x     Document Type: Article

References (31)

1. Aoki, H., Kodama, M., Tani, T. and Hanasawa, K. (1994) Treatment of sepsis by extracorporeal elimination of endotoxin using polymyxin B-immobilized fiber. Am. J. Surg 167, 412-417.
2. Barton, M.H. and Moore, J.N. (1994) Pentoxifylline inhibits mediator synthesis in an equine in vitro whole blood model of endotoxemia. Circ. Shock 44, 216-220.
3. Barton, M.H., Moore, J.N. and Norton, N. (1997a) Effects of pentoxifylline infusion on response of horses to in vivo challenge exposure with endotoxin. Am. J. vet. Res. 58, 1300-1307.
4. Barton, M.H., Ferguson, D., Davis, P.J. and Moor, J.N. (1997b) The effects of pentoxifylline infusion on plasma 6-keto-prostaglandin F1 alpha and ex vivo endotoxin-induced tumour necrosis factor activity in horses. J. vet. Pharmacol. Ther. 20, 487-492.
5. Barton, M., Bruce, E., Moore, J., Norton, N., Anders, B. and Morris, D. (1998) Effect of tumor necrosis factor antibody given to horses during early experimentally induced endotoxemia. Am. J. vet. Res. 59, 792-797.
6. Baskett, A., Barton, M.H., Norton, N., Anders, B. and Moore, J.N. (1997) Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses. Am. J. vet. Res. 58, 1291-129.
7. Bertone, J.J., Gossett, K.A., Shoemaker, K.E., Bertone, A.L. and Schneiter, H.L. (1990) Effect of hypertonic vs isotonic saline solution on responses to sublethal Escherichia coli endotoxemia in horses. Am. J. vet. Res. 51, 999-1007.
8. Bone, R.C., Balk, R.A., Fein, A.M., Perl, T.M., Wenzel, R.P., Reines, H.D., Quenzer, R.W., Iberti, T.J., Macintyre, N. and Schein, R.M. (1995) A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: results of a prospective, multicenter, randomized, controlled trial. The E5 Sepsis Study Group [see comments] [published erratum appears in Crit Care Med 23, 1616]. Crit. Care Med. 23, 994-1006.
9. Cargile, J.L., MacKay, R.J., Dankert, J.R. and Skelley, L. (1995a) Effect of treatment with a monoclonal antibody against equine tumor necrosis factor (TNF) on clinical, hematologic, and circulating TNF responses of miniature horses given endotoxin. Am. J. vet. Res. 56, 1451-1549.
10. Cargile, J.L., MacKay, R.J., Dankert, J.R. and Skelley, L. (1995b) Effects of tumor necrosis factor blockade on interleukin 6, lactate, thromboxane, and prostacyclin responses in miniature horses given endotoxin. Am. J. vet. Res. 56, 1445-1450.
11. Carrick, J.B., Morris, D.D. and Moore, J.N. (1993) Administration of a receptor antagonist for platelet-activating factor during equine endotoxaemia. Equine vet. J. 25, 152-157.
12. Durando, M.M., MacKay, R.J., Linda, S. and Skelley, L.A. (1994) Effects of polymyxin B and Salmonella typhimurium antiserum on horses given endotoxin intravenously. Am. J. vet. Res. 55, 921-927.
13. Eades, S.C. and Moore, J.N. (1993) Blockade of endotoxin-induced cecal hypoperfusion and ileus with an alpha 2 antagonist in horses. Am. J. vet. Res. 54, 586-590.
14. Edens, L. and Cargil, J. (1997) Medical management of colic. In: Current Therapy in Equine Medicine. Ed: N. Robinson. W.B. Saunders, Philadelphia. pp 182-191.
15. Greenman, R.L., Schein, R.M., Martin, M.A., Wenzel, R.P., MacIntyre, N.R., Emmanuel, G., Chmel, H., Kohler, R.B., McCarthy, M. and Plouffe, J. (1991) A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. The XOMA Sepsis Study Group [see comments]. J. Am. med. Ass. 266, 1097-1102.
16. Han, J., Mathison, J.C., Ulevitch, R.J. and Tobias, P.S. (1994) Lipopolysaccharide (LPS) binding protein, truncated at Ile-197, binds LPS but does not transfer LPS to CD14. J. Biol. Chem. 269, 8172-8175.
17. Hanasawa, K., Tani, T., Oka, T., Yoshioka, T., Aoki, H., Endom Y. and Kodama, M. (1988) Selective removal of endotoxin from the blood by extracorporeal hemoperfusion with polymyxin B immobilized fiber. Prog. Clin. Biol. Res. 264, 337-341.
18. Henry, M.M., Moore, J.N. and Feldman, E.B. (1990) Effect of dietary alpha-linoleic acid on equine monocyte procoagulant activity and eicosanoid synthesis. Circ. Shock 32, 173-188.
19. Henry, M.M., Moore, J.N. and Fischer, J.K. (1991) Influence of an omega-3 fatty acid-enriched ration on in vivo responses of horses to endotoxin. Am. J. vet. Res. 52, 523-527.
20. Jarvis, B.W., Lichenstein, H. and Qureshi, N. (1997) Diphosphoryl lipid A from Rhodobacter sphaeroides inhibits complexes that form in vitro between lipopolysaccharide (LPS)-binding protein, soluble CD14, and spectrally pure LPS. Infect. Immun. 65, 3011-3016.
21. Kodama, M., Tani, T., Maekaw, K, Hirasaw, H., Otsuka, T., Takahashi, Y. and Kaneko, M. (1995) [Endotoxin eliminating therapy in patients with severe sepsis-direct hemoperfusion using polymyxin B immobilized fiber column]. Nippon Geka Gakkai Zasshi 96, 277-285.
22. Moore, J.N. and Morris, D.D. (1992) Endotoxemia and sepsis in horses: Experimental and clinical correlates. J. Am. vet. med. Ass. 200, 1903-1914.
23. Moore, J.N., Hardee, M.M. and Hardee, G.E. (1986) Modulation of arachidonic acid metabolism in endotoxemic horses: comparison of flunixin meglumine, phenylbutazone and a selective thromboxane synthetase inhibitor. Am. J. vet. Res. 47, 110-113.
24. Morris, D.D., Henry, M.M., Moore, J.N. and Fischer, K. (1989) Effect of linolenic acid on endotoxin-induced thromboxane and prostacyclin production by equine peritoneal macrophages. Circ. Shock 29, 311-318.
25. Parviaianen, A. (1998) Evaluation of polymyxin B sulfate in an ex vivo model of endotoxemia. In: 6th Equine Colic Research Symposium., Athens, Georgia.
26. Semrad, S.D. and Moore, J.N. (1987) Effects of multiple low doses of flunixin meglumine on repeated endotoxin challenge in the horse. Prostaglandins. Leukot Med. 27, 169-181.
27. Semrad, S.D., Hardee, G.E., Hardee, M.M. and Moore, J.N. (1987) Low dose flunixin meglumine: effects on eicosanoid production and clinical signs induced by experimental endotoxaemia in horses. Equine vet. J. 19, 201-206.
28. Shuster, R., Traub-Dargatz, J. and Baxter, G.M. (1997) Survey of diplomates of the American College of Veterinary Internal Medicine and the American College of Veterinary Surgeons regarding clinical aspects and treatment of endotoxemia in horses. J. Am. vet. med. Ass. 210, 87-92.
29. Spier, S., Lavoie, J.P. and Cullor, J.S. (1989) Protection against clinical endotoxemia in horses by using plasma containing antibody to an Re mutant of E. coli. Circ. Shock 28, 235-248.
30. Wright, S.D., Ramos, R.A., Tobias, P.S., Ulevitch, R.J. and Mathison, J.C. (1990) CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein [see comments]. Science 249, 1431-1433.
31. Ziegler, E.J., Fisher, C.J. Jr., Sprung, C.L., Straube, R.C., Sadoff, I.C., Foulke, G.E., Wortel, C.H., Fink, M.P., Dellinger, R.P. and Teng, N.N. (1991) Treatment of gram-negative bacteremia and septic shock with HA-1A human monoclonal antibody against endotoxin. A randomized, double-blind, placebo-controlled trial. The HA-1A Sepsis Study Group [see comments]. N. Engl. J. Med. 324, 429-436.