Coding block and 5' leader cistron polymorphisms of the β2-adrenergic receptor

Clinical and Experimental Allergy, Supplement

Volumn 29, Issue 4, 1999, Pages 43-45

  McGraw, D W ^a   Liggett, S B ^a,b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

2 adrenergic receptor; Asthma; Downregulation; Polymorphism

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR;

ASTHMA; CISTRON; CONFERENCE PAPER; DNA POLYMORPHISM; GENE LOCUS; HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION;

ANIMALS; ASTHMA; COS CELLS; GENES; HUMANS; PHENOTYPE; POLYMORPHISM, GENETIC; RECEPTORS, ADRENERGIC, BETA-2;

EID: 0033458771     PISSN: 09602178     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (11)

1. 2-adrenergic receptor impart distinct agonist-promoted regulatory properties. Biochemistry 1994; 33:9414-9.
2. 2-adrenergic receptor within the fourth transmembrane domain alters ligand binding and functional properties of the receptor. J Biol Chem 1993; 268:23116-21.
3. 2-adrenergic receptor regulate receptor expression. J Clin Invest 1998; 102:1927-32.
4. 2-adrenergic receptor mRNA inhibits receptor synthesis. J Biol Chem 1994; 269:4497-505.
5. 2-adrenergic receptor in nocturnal and non-nocturnal asthma: evidence that Gly16 correlates with the nocturnal phenotype. J Clin Invest 1995; 95:1635-41.
6. 2-adrenoceptor and response to albuterol in children with and without a history of wheezing. J Clin Invest 1997; 100:3184-8.
7. Tan S, Hall IP, Dewar J, Dow E, Lipworth B. Association between beta-2 adrenoceplor polymorphism and susceptibility to bronchodilator desensitisation in moderately severe stable asthmatics. Lancet 1997; 350:995-9.
8. 2-adrenergic receptor haplotypes in mild, moderate and fatal/near fatal asthma. Am J Respir Crit Care Med 1998; 158:787-91.
9. 2-adrenoceptor polymorphism with lower airway reactivity in asthmatic subjects. Lancet 1995; 345:1213-4.
10. 2-adrenoceptor polymorphism is associated with elevated immunoglobulin E levels in asthmatic families. J Allergy Clin Immunol 1997; 100:261-5.
11. Fedyk ER, Looney AA, Phipps RP. Regulation of IgE an cytokine production by cAMP: implications for extrinsic asthma. Clin Immunol Immunopathol 1996; 81:101-13.