Night-time quiescence and morning activation in the human colon: Effect on transit of dispersed and large single unit formulations

European Journal of Gastroenterology and Hepatology

Volumn 11, Issue 12, 1999, Pages 1379-1385

  Hebden, John M ^a   Gilchrist, Peter J ^d   Blackshaw, Elaine ^b   Frier, Malcolm E ^b   Perkins, Alan C ^b   Wilson, Clive G ^d   Spiller, Robin C ^a,c  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^c QUEEN S MEDICAL CENTRE   (United Kingdom)

^d NONE

Author keywords

Colon transit; Drug delivery; Sleep

Indexed keywords

DRUG; INDIUM 111; RESIN; TECHNETIUM 99M;

ARTICLE; CIRCADIAN RHYTHM; CLINICAL TRIAL; COLON; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG DOSAGE FORM; DRUG FORMULATION; FEMALE; GASTROINTESTINAL TRACT SCINTISCANNING; GASTROINTESTINAL TRANSIT; HUMAN; HUMAN EXPERIMENT; INTESTINE TRANSIT TIME; MALE; NIGHT SLEEP; NORMAL HUMAN; PARTICULATE MATTER; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; WAKEFULNESS;

EID: 0033452134     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-199912000-00007     Document Type: Article

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