The effect of intravesical mitomycin C on the recurrence of superficial (Ta-T1) bladder cancer. A Hungarian multicenter study

International Urology and Nephrology

Volumn 31, Issue 4, 1999, Pages 451-456

  Kondas J ^a   Kiss, L ^a   Hatar A ^a   Kiss, A ^a   Lukacs T ^a   Szeldeli, P ^a   Torzsok F ^a   Bodrogi, I ^a  

^a Hungarian Society of Oncologists   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

MITOMYCIN C;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BLADDER CARCINOMA; CANCER CHEMOTHERAPY; CANCER RECURRENCE; DRUG EFFECT; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; TRANSURETHRAL RESECTION;

ADMINISTRATION, INTRAVESICAL; ANTIBIOTICS, ANTINEOPLASTIC; CARCINOMA, TRANSITIONAL CELL; HUMANS; HUNGARY; MITOMYCIN; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; REOPERATION; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; URINARY BLADDER NEOPLASMS;

EID: 0033451777     PISSN: 03011623     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007155026151     Document Type: Article

References (17)

1. Aeikens, B., Niermann, R., Schindler, E.: Investigation about the penetration depth in the normal bladder wall and tumour by local instillation of mitomycin into the urinary bladder. Urol. Int , 37, 389 (1982).
2. Akaza, H., Kurth, K. H., Williams, R., Hinotsu, S., Jewett, M. A. S., Naito, K., Okada, K., Schellhammer, P. F., van Velthoven, R. F., Witjes, J. A.: Intravesical chemotherapy and immunotherapy for superficial tumors: Basic mechanism of action and future direction. Urologic Oncology, 4, 121 (1998).
3. Beretta, G.: Mitomycin C: Current Status. Edizioni Minerva Medica, Turin 1996, pp. 97-100.
4. Farrow, C. M., Utz, D. C., Rife, C. C.: Morphological and clinical observation of patients with early bladder cancer treated with total cystectomy. Cancer Res., 36, 2495 (1976).
5. Flüchter, S: H., Harzmann, R., Bichler, K. H.: Local mitomycin C therapy of transitional cell carcinoma of the bladder - serum resorption study and clinical results. In: Ogawa, M., Rozencweig, M., Staquet, M. J. (eds): Mitomycin C. Current Impact on Cancer Chemotherapy. Excerpta Medica, Amsterdam 1982, p. 143.
6. Imperial Cancer Research Fund: Cancer Statistics Fact Sheet (May 1995).
7. Kurth, K. H. et al.: Factors affecting recurrence and progression in superficial bladder tumours. Eur. J Cancer, 31A, 1840 (1995).
8. Lamm, D. L., Griffith, J. G.: The place of intravesical chemotherapy as defined by results of prospective randomized studies (substances and treatment schemes). Prog. Clin. Biol. Res., 378, 43 (1992).
9. Lamm, D. L.: Long-term results of intravesical therapy for superficial bladder cancer. Urol. Clin. North Am., 19, 573 (1992).
10. Lamm, D. L., van der Meijden, A. P. M., Akaza, H. et al.: Intravesical chemotherapy and immunotherapy: how do we assess their effectiveness and what are their limitations and uses? Int. J. Urol., 2 (Suppl. 2), 23 (1995).
11. Lown, J. W.: The molecular mechanism of antitumor action of mitomycins. In: Carter, S. K., Crooke, S. T., Alder, N. A. (eds): Mitomycin C: Current Status and New Developments. Academic Press, New York 1979, p. 5.
12. Pawinski, A. et al.: A combined analysis of EORTC and MRC clinical trials for the prophylactic treatment of stage TaT1 bladder cancer. J. Urol , 156, 1934 (1996).
13. Soloway, M. S., Masters, S.: Urothelial susceptibility to tumor cell implantation. Influence of cauterization. Cancer, 46, 1158 (1980).
14. Tolley, D. A., Parmar, M. K. B., Grigor, K. M., Lallemand, G. and The Medical Research Council Superficial Bladder Cancer Working Party: The effect of intravesical mitomycin C on recurrence of newly diagnosed superficial bladder cancer: A further report with 7 years of followup. J. Urol., 155, 1233 (1996).
15. Vegt, P. D: J., Witjes, J. A., Witjes, W. P. J., Doesburg, W. H., Debruyne, F. M. J., van der Meijden, A. P. M.: A randomized study of intravesical mitomycin C, bacillus Calmette-Guerin Tice and bacillus Calmette-Guerin RIVM treatment in pTa-pT1 papillary carcinoma and carcinoma in situ of the bladder. J. Urol., 153, 929 (1995).
16. Wajsman, Z., Dhafir, R. A., Pfeffer, M., MacDonald, S., Block, A., Dragone, N., Pontes, E.: Studies of mitomycin C absorption after intravesical treatment of superficial bladder tumors. J. Urol., 132, 30 (1984).
17. Witjes, J. A.: Superficial bladder cancer, including T1G3 disease. Eur. Urol., 34/2 (Curric. Urol. 6.2: 1-6) (1998).