Increased mortality in hemodialyzed patients with elevated serum troponin T: A one-year outcome study

Clinical Biochemistry

Volumn 32, Issue 8, 1999, Pages 647-652

  Ooi, Daylily S ^a,d   Veinot, John P ^a,d   Wells, George A ^b,d   House, Andrew A ^c,e  

^a UNIVERSITY OF OTTAWA   (Canada)

^b OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^c LONDON HEALTH SCIENCES CENTRE   (Canada)

^d UNIVERSITY OF OTTAWA   (Canada)

^e UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

End stage renal disease; Hemodialysis; Long term mortality; Troponin T

Indexed keywords

TROPONIN T;

ADULT; AGE; AGED; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; FEMALE; HEMODIALYSIS; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CAUSE OF DEATH; COHORT STUDIES; CORONARY DISEASE; FEMALE; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RENAL DIALYSIS; SURVIVAL RATE; TIME FACTORS; TREATMENT OUTCOME; TROPONIN T;

EID: 0033450747     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9120(99)00064-8     Document Type: Article

References (31)

1. Hafner G., Thome-Kromer B., Schaube J., et al. Cardiac troponins in serum in chronic renal failure [Letter]. Clin Chem. 40:1994;1790-1791.
2. Bhayana V., Gougoulias T., Cohoe S., Henderson A.R. Discordance between results for serum troponin T and troponin I in renal disease. Clin Chem. 41:1995;312-317.
3. Li D., Keffer J., Corry K., Vazquez M., Jialal I. Nonspecific elevation of troponin T levels in patients with chronic renal failure. Clin Biochem. 28:1995;474-477.
4. Collinson P.O., Stubbs P.J., Rosalki S.B. Cardiac troponin T in renal disease [Letter]. Clin Chem. 41:1995;1671-1673.
5. Frankel W.L., Herold D.A., Ziegler T.W., Fitzgerald R.L. Cardiac troponin T is elevated in asymptomatic patients with chronic renal failure. Am J Clin Pathol. 106:1996;118-123.
6. Apple F.S., Sharkey S.W., Hoeft P., et al. Prognostic value of serum cardiac troponin I and T in chronic dialysis patients a 1-year outcomes analysis . Am J Kidney Dis. 29:1997;399-403.
7. Bodor G.S., Survant L., Voss E.M., Smith S., Porterfield D., Apple F.S. Cardiac troponin T composition in normal and regenerating skeletal muscle. Clin Chem. 43:1997;476-484.
8. McLaurin M.D., Apple F.S., Voss E.M., Herzog C.A., Sharkey S.W. Cardiac troponin I, cardiac troponin T, and creatine kinase MB in dialysis patients without ischemic heart disease evidence of cardiac troponin T expression in skeletal muscle . Clin Chem. 43:1997;976-982.
9. Apple F.S., Maturen A.J., Mullins R.E., et al. Multicentre clinical and analytical evaluation of the AxSYM troponin-I immunoassay to assist in the diagnosis of myocardial infarction. Clin Chem. 45:1999;206-212.
10. Townsend P.J., Barton P.J.R., Yacoub M.H., Farza H. Molecular cloning of human cardiac troponin T isoforms expression in developing and failing heart . J Mol Cell Cardiol. 27:1995;2223-2236.
11. Ricchiuti V., Voss E.M., Ney A., Odland M., Anderson P.A.W., Apple F.S. Cardiac troponin T isoforms expressed in renal diseased skeletal muscle will not cause false-positive results by the second generation cardiac troponin T assay by Boehringer Mannheim. Clin Chem. 44:1998;1919-1924.
12. Ooi D.S., House A.A. Cardiac troponin T in hemodialyzed patients. Clin Chem. 44:1998;1410-1416.
13. Department of Surveillance and Epidemiology. Epi Info, version 6. Atlanta, Georgia: CDC, 1995.
14. SAS version 6.12. Carey, North Carolina: SAS Institute Inc., 1989-96.
15. United States Renal Data System 1998 annual data report. Causes of death. Am J Kidney Dis 1998; 32: S81-8.
16. Herzog C.A., Ma J.Z., Collins A.J. Poor long-term survival after acute myocardial infarction among patients on long-term dialysis. N Engl J Med. 339:1998;799-805.
17. Stehman-Breen C.O., Emerson S., Gretch D., Johnson R.J. Risk of death among chronic dialysis patients infected with hepatitis C virus. Am J Kidney Dis. 32:1998;629-634.
18. United States Renal Data System 1998 annual data report. Patient mortality and survival. Am J Kidney Dis 1998; 32: S69-80.
19. Foley R.N., Parfrey P.S., Harnett J.D., Kent G.M., Murray D.C., Barre P.E. Impact of hypertension on cardiomyopathy, morbidity and mortality in end-stage renal disease. Kidney Int. 49:1996;1379-1385.
20. Owen W.F. Jr, Lew N.L., Liu Y., Lowrie E.G., Lazarus J.M. The urea reduction ratio and serum albumin concentrations as predictors of mortality in patients undergoing hemodialysis. N Engl J Med. 329:1993;1001-1006.
21. McClellan W.M., Soucie J.M., Flanders W.D. Mortality in end-stage renal disease is associated with facility-to-facility differences in adequacy of hemodialysis. J Am Soc Nephrol. 9:1998;1940-1947.
22. Porter G.A., Norton T., Bennett W.B. Troponin T, a predictor of death in chronic haemodialysis patients. Eur Heart J. 19:1998;N34-N37.
23. Haller C, Zehelein J, Remppis A, Kubler W, Katus HA. Cardiac troponin T in patients with renal failure [Abstract]. J Am Coll Cardiol 1997; 29(S): 234A.
24. Christenson R.H., Duh S.-H., Newby K., et al. Cardiac troponin T and cardiac troponin I relative values in short-term risk stratification of patients with acute coronary syndromes . Clin Chem. 44:1998;494-501.
25. Sabbah H.N., Sharov V.G. Apoptosis in heart failure. Prog Cardiovasc Dis. 40:1998;549-562.
26. Setsuta K., Seino Y., Takano T., Takahashi N., Kishida H. Clinical significance of elevated levels of cardiac troponin T detected by second generation assay in patients with congestive heart failure. J Am Coll Cardiol. 29:(S):1997;102A.
27. Wrobel K., Wrobel K., Garay-Sevilla M.E., Nava L.E., Malacara J.M. Novel analytical approach to monitoring advanced glycosylation end products in human serum with on-line spectrophotometric and spectrofluorometric detection in a flow system. Clin Chem. 43:1997;1563-1569.
28. Vlassara H. Recent progress in advanced glycation end products and diabetic complications. Diabetes. 46:1997;S19-S25.
29. Hou F.F., Chertow G.M., Kay J., et al. Interaction between beta-2-microglobulin and advanced glycation end products in the development of dialysis related amyloidosis. Kidney Int. 51:1997;1514-1519.
30. Ohman E.M., Armstrong P.W., Christenson R.H., et al. Cardiac troponin T levels for risk stratification in acute myocardial ischemia. N Engl J Med. 335:1996;1333-1341.
31. Antman E.M., Tanasijevic M.J., Thompson B., et al. Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes. N Engl J Med. 335:1996;1342-1349.