Escin in pharmaceutical oral dosage forms: Quantitative densitometric HPTLC determination

Farmaco

Volumn 54, Issue 11-12, 1999, Pages 728-732

  Costantini, Alberto ^a  

^a Stabilimento Chimico Farmaceutico M   (Italy)

Author keywords

Analysis; Densitometry; Escin; Oral dosage forms; Thin layer chromatography

Indexed keywords

ESCIN; SAPONIN;

ARTICLE; DENSITOMETRY; DRUG DETERMINATION; DRUG DOSAGE FORM; DRUG STRUCTURE; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; TABLET; THIN LAYER CHROMATOGRAPHY;

ADMINISTRATION, ORAL; CHROMATOGRAPHY, THIN LAYER; DENSITOMETRY; DOSAGE FORMS; ESCIN; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS;

EID: 0033436359     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(99)00090-7     Document Type: Article

References (18)

1. Wulff G., Tschesche R. Triterpenes. XXVI. On the structure of the horse-chestnut saponin (aescin) and the aglicones of various glycosides. Tetrahedron. 25:1969;415-436.
2. Pittler M.H., Ernst E. Horse-chestnut seed extract for chronic venous insufficiency. A criteria-based systematic review. Arch. Dermatol. 134:1998;1356-1360.
3. Mingrino S., Scanarini M. Anti-edema effect of escin at the cerebral level. Minerva Anestesiol. 44:1978;355-360.
4. Hemmer R. Therapy of brain edema in craniocerebral trauma. Der Unfallchirurg. 88:1985;93-96.
5. Tolino A. Medical treatment of the anorectal varicose syndrome in gynecology and obstetrics. Minerva Ginecol. 31:1979;169-174.
6. Bertrand G.L. Experimental study of beta-aescine (1) gel in oral and periodontal surgery. Rev. Odontostomatol. Midi Fr. 39:1981;211-216.
7. Proserpio G., Gatti S., Genesi P. Cosmetic use of horse-chestnut (Aesculus hippocastanum) extracts, of escin and of the cholesterol/escin complex. Fitoterapia. 51:1980;113-128.
8. Von Kammerl E., Schlemmer W. Automated chemical determination of escin in horse-chestnut extract and in pharmaceutical preparations. Pharm. Ind. 34:1972;356-358.
9. Hentschel C., Schossler W., Liebrich G., Brattstrom A Enzyme immuno assay for quantitative determination of beta-aescin in human serum. Pharmazie. 49:1994;929-930.
10. Lehtola T., Huhtikangas A. Radioimmunoassay of aescin, a mixture of triterpene glycosides. J. Immunoass. 11:1990;17-30.
11. Uberti E., Martinelli E.M., Pifferi G. TLC-densitometric analysis of aescin in ointments. Fitoterapia. 61:1990;57-60.
12. Mete Kockar O., Mustafa K., Serap K., Berrin B., Husnu Baser K. Quantitative determination of escin. A comparative study of HPLC and TLC-densitometry. Fitoterapia. 65:1994;439-443.
13. Vanhaelen M., Vanhaelen-Fastre R. Quantitative determination of biologically active constituents in medicinal plant crude extracts by thin-layer chromatography-densitometry. I. Aesculus hippocastanum L., Arctostaphyllos uva-ursi Spreng, Fraxinus excelsior L., Gentiana lutea L., Glycyrrhiza glabra L., Hamamelis virginiana L., Hypericum perforatum L., Olea europea L., Salix alba L. and Silybum marianum Gaertn. J. Chromatogr. 281:1983;263-271.
14. Pietta P., Mauri P., Maffei R., Carini M. High-performance liquid chromatography analysis of β-escin. J. Chromatogr. 478:1989;259-263.
15. Renger B. Quantitative densitometric HPTLC determination of triterpenic saponins (escin) in horse-chestnut extracts. J. Planar Chromatogr. 3:1990;160-162.
16. Griffini A., Lolla E., Peterlongo F. Liquid chromatography-thermospray mass spectrometry analysis of beta-escin. Fitoterapia. 68:1997;520-526.
17. Kaiser R.E. Modern quantitation in planar chromatography. J. Planar Chromatogr. 4:1989;323-326.
18. Poole C.F., Poole S.K. Instrumental thin-layer chromatography. Anal. Chem. 66:1994;27-37.