Determination of agaritine in cultivated mushrooms using high performance liquid chromatography with fluorometric detection

Italian Journal of Food Science

Volumn 11, Issue 1, 1999, Pages 39-46

  Burini, G ^a   Curini, M ^a   Marcotullio, M C ^a   Policicchio, P ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Agaricus bisporus; Agaritine; Fluorometric detection; HPLC determination; Pleorotus ostreatus

Indexed keywords

AGARICUS BISPORUS; BASIDIOMYCOTA;

EID: 0033435859     PISSN: 11201770     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Chiarlo B., Cajelli E. and Acerbo C. 1979. The presence of agaritine in a mushroom (Agaricus bisporus) commonly cultivated in Italy. Fitoterapia. 50: 111.
2. Epsin J.C., Jolivet S. and Wichers J. 1998. Inhibition of mushroom polyphenol oxidase by agaritine. J. Agric. Food Chem. 46: 2976.
3. Gigliotti H. 1963. Studies on the γ-glutamyltransferase and arylhydrazine oxidase activities of Agaricus bisporus. Ph. D. Dissertation, University of Michigan, Ann Arbor.
4. Gigliotti H. and Levenberg B. 1964. Studies on the γ-glutamyltransferase of Agaricus bisporus. J. Biol. Chem. 239: 2274.
5. Kelly R.B., Daniels E.G. and Hinman J.W. 1962. Agaritine: Isolation, degradation and synthesis. J. Org. Chem. 27: 3229.
6. La Rue T. 1977. Naturally occurring compounds containing nitrogen-nitrogen bond. Lloydia 40: 307.
7. Levenberg B. 1961. Structure and enzymatic cleavage of agaritine, a phenylhydrazide of L-glutamic acid isolated from Agaricaceae. J. Am. Chem. Soc. 83: 503.
8. Liu J.W., Speroni J.J., Beelman R.B. and Lineback D.R. 1982. Agaritine content of fresh and processed mushrooms [Agaricus bisporus (Lange) Imbach]. J. Food Science 47: 1542.
9. Nefkens G.H.L. and Nirvard R.J.F. 1964. A new method for the synthesis of α-esters of N-acylglutamic acids. Recueil 83: 199.
10. Natori S. 1987. Mushroom hydrazine.(Meiji Coll. Phar. Tanashi, Japan 188) Bioact. Mol. 2: 127.
11. Shepard S.E., Gunz D. and Schlattler C. 1995. Genotoxicity of agaritine in the lacI transgenic mouse mutation assay: evaluation of the health risk of mushroom consumption. Food Chem. Toxicol. 33: 257.
12. Speroni J.J. and Beelman R.B. 1982. High performance liquid chromatographic determination of agaritine in cultivated mushrooms. J. Food Science 47: 1539.
13. Sumitani H., Suekani S. and Sakay Y. 1992. Pre-column o-phthalaldehyde derivatization and reversed-phase liquid chromatography of S-methylmethioninesulfonium in Satsuma mandarin juice. Journal of AOAC International vol. 75: 77.
14. Toth B. 1979. Mushroom hydrazines: occurrence, metabolism, carcinogenesis and environmental implications, p.57. Proc. Int. Sym. Princess Tamakatsu Cancer Res. Fun.
15. Toth B. 1983. Carcinogens in edible mushrooms. Carcinog. Mutagens Environm. 3: 99.
16. Toth B. 1987. Cancer induction by the sulfate form of 4-(hydroxymethyl)benzenediazonium ion of Agaricus bisporus. In vivo 1: 39.
17. Toth B. and Gannett P. 1993. Agaricus bisporus: an assessment of its cancerogenic potency. Mycopathologia 124: 73.
18. Wallcave L., Nagel D.L., Raha C.R., Jae H.S., Bronzyk S., Kupper R. and Toth B. 1979. An improved synthesis of agaritine. J. Org. Chem. 44: 3752.
19. Walton K., Coombs M.M., Catteral F.S., Walker R. and Ioannides C. 1997a. Bioactivation of the mushroom hydrazine, agaritine, to intermediates that bind covalenty to proteins and induce mutations in the Ames test. Carcinogenesis 18: 1603.
20. Walton K., Coombs M.M., Walker R. and Ioannides C. 1997b. Bioactivation of the mushroom hydrazines to mutagenic products by mammalian and fungal enzymes. Mutat. Res. 381: 131.