Metabolic and hormonal responses to exercise in type 1 diabetic patients during continuous subcutaneous, as compared to continuous intraperitoneal, insulin infusion

Diabetes and Metabolism

Volumn 25, Issue 6, 1999, Pages 491-497

  Oskarsson, P R ^a   Lins, P E ^a   Henriksson, H Wallberg ^b   Adamson, U C ^a  

^a DANDERYD HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Exercise; Glucagon; Insulin infusion; Intra peritoneal; Pump treatment; Subcutaneous; Type 1 diabetes

Indexed keywords

ADRENALIN; GLUCAGON; GLUCOSE; GROWTH HORMONE; HEMOGLOBIN A1C; HYDROCORTISONE; INSULIN; NORADRENALIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EXERCISE; FEMALE; GLUCAGON BLOOD LEVEL; GLUCOSE BLOOD LEVEL; HORMONE RESPONSE; HUMAN; HYPOGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN INFUSION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; SUBCUTANEOUS DRUG ADMINISTRATION;

ADULT; BLOOD GLUCOSE; BLOOD PRESSURE; C-PEPTIDE; DIABETES MELLITUS, TYPE 1; EPINEPHRINE; EQUIPMENT DESIGN; EXERCISE; FEMALE; GLUCAGON; HEMOGLOBIN A, GLYCOSYLATED; HUMAN GROWTH HORMONE; HUMANS; HYDROCORTISONE; INSULIN INFUSION SYSTEMS; MALE; MIDDLE AGED; NOREPINEPHRINE; PULSE;

EID: 0033430388     PISSN: 03381684     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Koivisto VA, Tronier B. Postprandial blood glucose response to exercise in type I diabetes: comparison between pump and injection therapy. Diabetes Care, 1983, 6, 436-440.
2. Kemmer FW. Prevention of hypoglycemia during exercise in type I diabetes. Diabetes Care, 1992, 15, 1732-1735.
3. Mitchell TH, Abraham G, Schiffrin A, Leiter LA, Marliss EB. Hyperglycemia after intense exercise in IDDM subjects during continuous subcutaneous insulin infusion. Diabetes Care, 1988, 11, 311-317.
4. Edelmann E, Staudner V, Bachmann W, Walter H, Haas W, Mehnert H. Exercise-induced hypoglycaemia and subcutaneous insulin infusion. Diabetic Med, 1986, 3, 526-531.
5. Sonnenberg GE, Kemmer FW, Berger M. Exercise in type 1 (insulin-dependent) diabetic patients treated with continuous subcutaneous insulin infusion. Prevention of exercise induced hypoglycaemia. Diabetologia, 1990, 33, 696-703.
6. Fernqvist E, Linde B, Östman J, Gunnarsson R. Effects of physical exercise on insulin absorption in insulin-dependent diabetics. A comparison between human and porcine insulin. Clin Physiol, 1986, 6, 489-497.
7. Koivisto VA, Yki-Järvinen H, DeFronzo RA. Physical training and insulin sensitivity. Diabetes Metab, 1986, 1, 445-481.
8. Sotsky MJ, Shilo S, Shamoon H. Regulation of counterregulatory hormone secretion in man during exercise and hypoglycemia. J Clin Endocrinol Metab, 1989, 68, 9-16.
9. Gooch BR, Abumrad NN, Robinson RP, Petrik M, Campbell D, Crofford OB. Exercise in insulin-dependent diabetes mellitus: the effect of continuous insulin infusion using the subcutaneous, intravenous, and intraperitoneal sites. Diabetes Care, 1983, 6, 122-128.
10. Nathan DM, Dunn FL, Bruch J, et al. Postprandial insulin profiles with implantable pump therapy may explain decreased frequency of severe hypoglycemia, compared with intensive subcutaneous regimens, in insulin-dependent diabetes mellitus patients. Am J Med, 1996, 100, 412-417.
11. Dunn FL, Nathan DM, Scavini M, Selam JL, Wingrove TG. Long-term therapy of IDDM with an implantable insulin pump. The Implantable Insulin Pump Trial Study Group. Diabetes Care, 1997, 20, 59-63.
12. Moberg EA, Kollind ME, Lins PE, Adamson UC. Estimation of blood-glucose variability in patients with insulin-dependent diabetes mellitus. Scand J Clin Lab Invest, 1993, 53, 507-514.
13. Wallberg-Henriksson H, Gunnarsson R, Henriksson J, Östman J, Wahren J. Influence of physical training on formation of muscle capillaries in type I diabetes. Diabetes, 1984, 33, 851-857.
14. Jeppsson JO, Jerntorp P, Sundkvist G, Englund H, Nylund V. Measurement of hemoglobin Alc by a new liquid-chromatographic assay: methodology, clinical utility, and relation to glucose tolerance evaluated. Clin Chem, 1986, 32, 1867-1872.
15. Modifiziert nach Noll, F. In: Bergmeyer HU, editor. Methoden der enzymatischen Analyse. Weinheim: Verlag Chemie; 1974. p. 1521.
16. Nakagawa S, Nakayama H, Sasaki T, Yoshino K, Yu YY. A simple method for the determination of serum free insulin levels in insulin-treated patients. Diabetes, 1973, 22, 590-600.
17. Hjemdahl P, Daleskog M, Kahan T. Determination of plasma catecholamines by high performance liquid chromatography with electrochemical detection: comparison with a radiocnzymatic method. Life Sci, 1979, 25, 131-138.
18. Heding LG. Radioimmunological determination of human C-peptide in serum. Diabelologia, 1975, 11, 541-548.
19. Lantto O, Lindbäck B, Aakvaag A, Damkjaer-Nielsen M, Pomoell UM, Björkhem I. Assay of cortisol with a radioimmunoassay method calibrated by isotope dilution-mass spectrometry. A Nordic collaborative study. Scand J Clin Lab Invest. 1983, 43, 433-437.
20. Cerasi E, Della Casa L, Luft R, Roovete A. Determination of human growth hormone (HGH) in plasma by a double antibody radioimmunoassay. Acta Endocrinol (Copenh), 1966, 53, 101-120.
21. Ahren B, Larsson H. Leptin - a regulator of islet function?: its plasma levels correlate with glucagon and insulin secretion in healthy women. Metabolism, 1997, 46, 1477-1481.
22. Shilo S, Sotsky M, Shamoon H. Islet hormonal regulation of glucose turnover during exercise in type 1 diabetes. J Clin Endocrinol Metab, 1990, 70, 162-172.
23. Sindelar DK, Chu CA, Venson P, Donahue EP, Neal DW, Cherrington AD. Basal hepatic glucose production is regulated by the portal vein insulin concentration. Diabetes, 1998, 47, 523-529.
24. Selam JL, Bergman RN, Raccah D, Jean-Didier N, Lozano J, Charles MA. Determination of portal insulin absorption from peritoneum via novel nonisotopic method. Diabetes, 1990, 39, 1361-1365.
25. Bratusch-Marrain PR. Waldhausl WK, Gasic S, Hofer A. Hepatic disposal of biosynthetic human insulin and porcine C-peptide in humans. Metabolism, 1984, 31, 151-157.
26. Sindelar DK, Chu CA, Neal DW, Cherrington AD. Interaction of equal increments in arterial and portal vein insulin on hepatic glucose production in the dog. Am J Physiol, 1997, 273, E972-980.
27. Yki-Järvinen H, Koivisto VA. Continuous subcutaneous insulin infusion therapy decreases insulin resistance in type 1 diabetes. J Clin Endocrinol Metab, 1984, 58, 659-666.
28. Tuttle KR, Marker JC, Dalsky GP, et al. Glucagon, not insulin, may play a secondary role in defense against hypoglycemia during exercise. Am J Physiol, 1988, 254, E713-719.
29. Bolli G, de Feo P, Compagnucci P, et al. Abnormal glucose counterregulation in insulin-dependent diabetes mellitus. Interaction of antiinsulin antibodies and impaired glucagon and epinephrine secretion. Diabetes, 1983, 32, 134-141.
30. Liu DT, Adamson UC, Lins PE, Kollind ME, Moberg EA, Andreasson K. Inhibitory effect of circulating insulin on glucagon secretion during hypoglycemia in type I diabetic patients. Diabetes Care, 1992, 15, 59-65.