Dystrophic psoriatic fingernails treated with 1% 5-fluorouracil in a nail penetration-enhancing vehicle: A double-blind study

Dermatology

Volumn 199, Issue 4, 1999, Pages 313-318

  De Jong, E M G J ^a   Menke, H E ^b   Van Praag, M C G ^b   Van De Kerkhof, P C M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SINT FRANCISCUS GASTHUIS   (Netherlands)

Author keywords

5 Fluorouracil; Belanyx; Nail; Psoriasis

Indexed keywords

BELANYX; FLUOROURACIL; PROPYLENE GLYCOL; PYRIMIDINE ANTAGONIST; UNCLASSIFIED DRUG; UREA;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG PENETRATION; FEMALE; FINGER NAIL; HUMAN; INFECTION; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; NAIL DYSTROPHY; ONYCHOLYSIS; PRIORITY JOURNAL; PSORIASIS; RANDOMIZED CONTROLLED TRIAL; RISK BENEFIT ANALYSIS; SKIN DISCOLORATION;

EID: 0033430379     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000018281     Document Type: Article

References (13)

1. de Jong EMGJ, Seegers BAMPA, Gulinck MK, Boezeman JBM, van de Kerkhof PCM: Psoriasis of the nails associated with disability in a large number of patients: Results of a recent interview with 1.728 patients. Dermatology 1996;193:300-303.
2. Bleeker JJ : Intradermal triamcinolone acetonide treatment of psoriatic nail dystrophy with Port O Jet (letter). Br J Dermatol 1975;92:479.
3. Yamamoto T, Katayama I, Nishioka K: Topical anthralin therapy for refractory nail psoriasis. J Dermatol 1998;25:231-233.
4. Kokelj F, Lavaroni G, Piraccini BM, Tosti A: Nail psoriasis treated with calcipotriol (MC903): An open study. J Dermatol Treat 1994;5:149-150.
5. Nyfors A: Benefits and adverse drug experiences during long-term methotrexate treatment of 248 psoriatics. Dan Med Bull 1978;25: 208-211.
6. Handfield-Jones SE, Boyle J, Harman RRM: Local PUVA treatment for nail psoriasis (letter). Br J Dermatol 1987;116:280-281.
7. Finnerty EF: Successful treatment of psoriasis of trie nails. Cutis 1979;23:43-44.
8. Lindelof B: Psoriasis of the nails treated with grenz rays: A double-blind, bilateral trial. Acta Derm Venereol (Stockh) 1989;69:80-82.
9. Luger A: 5-Fluorouracil in der Lokalbehandlung der Psoriasis. Z Haut Geschlechtskr 1969; 44:361-370.
10. Shelley WB: Onycholysis due to topical 5-fluorouracil. Acta Derm Venereol 1972;52:320-322.
11. Fritz K: Erfolgreiche Lokalbehandlung der Nagelpsoriasis mit 5-Fluorouracil. Z Haut Geschlechtskr 1989;64:1083-1088.
12. Fredriksson T: Topically applied fluorouracil in the treatment of psoriatic nails. Arch Dermatol 1974;110:735-736.
13. Fredriksson T, Lassus A, Salde L: Reproducibility of clinical trials of topical glucocorticosteroicls. Int J Dermatol 1983;22:536-539.