Partial liquid ventilation with and without inhaled nitric oxide in a newborn piglet model of meconium aspiration

American Journal of Respiratory and Critical Care Medicine

Volumn 160, Issue 6, 1999, Pages 1922-1927

  Barrington, Keith J ^a,b,c   Singh, Avash J ^a,b   Etches, Phillip C ^a,b   Finer, Neil N ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; GAS EXCHANGE; HEART OUTPUT; LUNG COMPLIANCE; LUNG HEMODYNAMICS; LUNG MECHANICS; LUNG VASCULAR RESISTANCE; MECONIUM ASPIRATION; NEWBORN; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; SWINE;

EID: 0033429497     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.160.6.9812068     Document Type: Article

References (35)

1. Finer, N. N., P. C. Etches, B. Kamstra, A. J. Tierney, A. Peliowski, and C. A. Ryan. 1994. Inhaled nitric oxide in infants referred for extracorporeal membrane oxygenation: dose response. J. Pediatr. 124:302-308.
2. The Neonatal Inhaled Nitric Oxide Study Group. 1997. Inhaled nitric oxide in full-term and nearly full-term infants with hypoxic respiratory failure. 1997. N. Engl. J. Med. 336:597-604.
3. Finer, N. N., and K. J. Barrington. 1998. Nitric oxide in respiratory failure in full-term and nearly full-term newborn infants (Cochrane Review). In The Cochrane Library, Issue 3. Update Software, Oxford.
4. Rufer, R., and H. L. Spitzer. 1974. Liquid ventilation in the respiratory distress syndrome. Chest 66:29S-30S.
5. Greenspan, J. S., M. R. Wolfson, S. D. Rubenstein, and T. H. Shaffer. 1990. Liquid ventilation of human preterm neonates. J. Pediatr. 117:106-111.
6. Tutuncu, A. S., N. S. Faithfull, and B. Lachmann. 1993. Comparison of ventilatory support with intratracheal perfluorocarbon administration and conventional mechanical ventilation in animals with acute respiratory failure. Am. Rev. Respir. Dis. 148:785-792.
7. Greenspan, J. S., W. W. Fox, S. D. Rubenstein, M. R. Wolfson, S. S. Spinner, T. H. Shaffer, and the Philadelphia Liquid Ventilation Consortium. 1997. Partial liquid ventilation in critically ill infants receiving extracorporeal life support. Pediatrics 99:E21-E25.
8. Leach, C. L., J. S. Greenspan, S. D. Rubenstein, T. H. Shaffer, M. R. Wolfson, J. C. Jackson, W. W. Fox, and S. S. Spinner. 1996. Partial liquid ventilation with perflubron in premature infants with severe respiratory distress syndrome. N. Engl. J. Med. 335:761-767.
9. Leach, C. L. B. P. Fuhrman, F. C. Morin III, and M. G. Rath. 1993. Perfluorocarbon-associated gas exchange (partial liquid ventilation) in respiratory distress syndrome: a prospective, randomized, controlled study. Crit. Care Med. 21:1270-1278.
10. Wolfson, M. R., N. E. Kechner, R. F. Roache, J. P. DeChadarevian, H. E. Friss, S. D. Rubenstein, and T. H. Shaffer. 1998. Perfluorochemical rescue after surfactant treatment: effect of perflubron dose and ventilatory frequency. J. Appl. Physiol. 84:624-640.
11. Leach, C. L., F. C. Morin III, B. P. Fuhrman, L. Hernan, M. Papo, D. Steinhorn, and R. H. Steinhorn. 1994. Efficacy and pharmacokinetics of nitric oxide inhalation during partial liquid ventilation with perflubron (Liquivent™) (abstract). Pediatr. Res. 35:394A.
12. Wilcox, D. T., P. L. Glick, H. L. Karamanoukian, F. C. Morin III, B. P. Fuhrman, and C. Leach. 1997. Partial liquid ventilation and nitric oxide in congenital diaphragmatic hernia. J. Pediatr. Surg. 32:1211-1215.
13. Wilcox, D. T., P. L. Glick, H. L. Karamanoukian, C. Leach, F. C. Morin III, and B. P. Fuhrman. 1995. Perfluorocarbon-associated gas exchange improves pulmonary mechanics, oxygenation, ventilation, and allows nitric oxide delivery in the hypoplastic lung congenital diaphragmatic hernia lamb model. Crit. Care Med. 23:1858-1863.
14. Zobel, G., B. Urlesberger, D. Dacar, S. Rodl, F. Reiterer, and I. Friehs. 1997. Partial liquid ventilation combined with inhaled nitric oxide in acute respiratory failure with pulmonary hypertension in piglets. Pediatr. Res. 41:172-177.
15. Shaffer, T. H., C. A. Lowe, V. K. Bhutani, and P. R. Douglas. 1984. Liquid ventilation: effects of pulmonary function in distressed meconium-stained lambs. Pediatr. Res. 18:47-52.
16. Thompson, A. E., B. P. Fuhrman, and J. Alan. 1993. Perfluorocarbon associated gas exchange (PAGE) in experimental meconium aspiration (MAS) (abstract). Pediatr. Res. 33:239A.
17. Foust, R., III, N. N. Tran, C. Cox, T. F. Miller, Jr., J. S. Greenspan, M. R. Wolfson, and T. H. Shaffer. 1996. Liquid assisted ventilation: an alternative ventilatory strategy for acute meconium aspiration injury. Pediatr. Pulmonol. 21:316-322.
18. Barrington, K. J., N. N. Finer, A. Peliowski, P. C. Etches, A. J. Graham, and W. K. Y. Chan. 1995. Inhaled nitric oxide improves oxygenation in a piglet model of meconium aspiration. Pediatr. Pulmonol. 20:27-33.
19. Clark, D. A., G. F. Nieman, J. E. Thompson, A. M. Paskanik, J. E. Rokhar, and C. E. Bredenberg. 1987. Surfactant displacement by meconium free fatty acids: an alternative explanation for atelectasis in meconium aspiration syndrome. J. Pediatr. 110:765-770.
20. Moses, D., B. A. Holm, P. Spitale, M. Liu, and G. Enhorning. 1991. Inhibition of pulmonary surfactant function by meconium. Am. J. Obstet. Gynecol. 164:477-481.
21. Evans, N., M. Klukow, and A. Currie. 1998. Range of echocardiographic findings in term neonates with high oxygen requirements. Arch. Dis. Child 78:F105-F111.
22. Sargent, J. W., and R. J. Seffl. 1970. Properties of perfluorinated liquids. Fed. Proc. 29:1699-1703.
23. Spitzer, H. L., G. Sachs, and L. C. Clark, Jr. 1970. Fluorocarbon effects on tissue metabolism. Fed. Proc. 29:1746-1750.
24. Stavis, R. L., M. R. Wolfson, C. Cox, N. Kechner, and T. H. Shaffer. 1998. Physiologic, biochemical, and histologic correlates associated with tidal liquid ventilation. Pediatr. Res. 43:132-138.
25. Modell, J. H., E. J. Newby, and B. C. Ruiz. 1970. Long-term survival of dogs after breathing oxygenated fluorocarbon liquid. Fed. Proc. 29:1731-1736.
26. Patel, M. M., P. Szanto, B. Yates, and D. M. Long. 1970. Survival and histopathologic changes in lungs of hamsters following synthetic liquid breathing. Fed. Proc. 29:1740-1745.
27. Modell, J. G., M. K. Tham, J. H. Modell, H. W. Calderwood, and B. C. Ruiz. 1973. Distribution and retention of fluorocarbon in mice and dogs after injection or liquid ventilation. Toxicol. Appl. Pharmacol. 26:86-92.
28. Kinsella, J. P., W. E. Truog, W. F. Walsh, R. N. Goldberg, E. E. Bancalari, D. E. Mayock, G. J. Redding, R. A. deLemos, S. Sardesai, D. C. McCurnin, S. G. Moreland, G. R. Cutter, and S. H. Abman. 1997. Randomized, multicenter trial of inhaled nitric oxide and high-frequency oscillatory ventilation in severe, persistent pulmonary hypertension of the newborn. J. Pediatr. 131:55-62.
29. Finer, N. N., and K. J. Barrington. 1997. Nitric oxide in respiratory failure in the newborn infant. Semin. Perinatol. 3:426-440.
30. Houmes, R. J., A. Hartog, S. J. Verbrugge, S. Bohm, and B. Lachmann. 1997. Combining partial liquid ventilation with nitric oxide to improve gas exchange in acute lung injury. Intensive Care Med. 23:163-169.
31. Uchida, T., K. Nakazawa, K. Yokoyama, K. Makita, and K. Amaha. 1998. The combination of partial liquid ventilation and inhaled nitric oxide in the severe oleic acid lung injury model. Chest 1658-1666.
32. Curtis, S. E., B. P. Fuhrman, D. F. Howland, M. DeFrancisis, and E. K. Motoyama. 1991. Cardiac output during liquid (perfluorocarbon) breathing in newborn piglets. Crit. Care Med. 19:225-230.
33. Lowe, C. A., and T. H. Shaffer. 1986. Pulmonary vascular resistance in the fluorocarbon-filled lung. J. Appl. Physiol. 60:154-159.
34. Hernan, L. J., B. P. Fuhrman, M. C. Papo, D. M. Steinhorn, C. L. Leach, N. Salman, P. R. Paczan, and B. Kahn. 1995. Cardiorespiratory effects of perfluorocarbon-associated gas exchange at reduced oxygen concentrations. Crit. Care Med. 23:553-559.
35. Doctor, A., J. C. Ibla, B. M. Grenier, D. Zurakowski, M. L. Ferretti, J. E. Thompson, C. W. Lillehei, and J. H. Arnold. 1998. Pulmonary blood flow distribution during partial liquid ventilation. J. Appl. Physiol. 84:1540-1550.