Does transforming growth factor β1 play a role in the pathogenesis of chronic allograft rejection?

Transplant International

Volumn 12, Issue 6, 1999, Pages 393-401

  Little, Dilly M ^a   Haynes, Lynn D ^b   Alam, Tausif ^b   Geraghty, James G ^b   Sollinger, Hans W ^b   Hullett, Debra A ^b  

^a CHURCHILL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Chronic rejection; Extracellular matrix; Intimal hyperplasia; Smooth muscle cell; Transforming growth factor 1

Indexed keywords

MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; AORTA GRAFT; ARTICLE; BLOOD LEVEL; CELL INFILTRATION; CONTROLLED STUDY; GRAFT REJECTION; HISTOLOGY; INFLAMMATORY CELL; ISOGRAFT; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; AORTA, ABDOMINAL; CHRONIC DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GRAFT REJECTION; HYPERPLASIA; INFLAMMATION; RATS; RATS, INBRED ACI; RATS, INBRED LEW; RNA, MESSENGER; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA; TRANSPLANTATION, HOMOLOGOUS; TUNICA INTIMA;

EID: 0033429108     PISSN: 09340874     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001470050248     Document Type: Article

References (38)

1. Border WA, Noble NA (1994) Transforming growth factor β in tissue fibrosis. N Engl J Med 331: 1286-1292
2. Border WA, Noble NA (1997) TGF-β in kidney fibrosis: a target for gene therapy. Kidney Int 51: 1388-1396
3. Cecka JM (1994) Outcome statistics of renal transplants with an emphasis on long-term survival. Clin Transpl 8: 324-327
4. Chomczynski P, Sacchi N (1987) Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159
5. Cook D (1987) Clinical Transplantation. UCLA Tissue Typing Laboratory, Los Angeles, pp 277
6. DeVito LD, Sollinger HW, Burlingham WJ (1990) Adsorption of cytotoxic anti-HLA antibodies with HLA class I immunosorbant beads. Transplantation 49: 925-931
7. Edwards DR, Murphy G, Reynolds JJ, Whitham SE, Docherty AJ, Angel P, Heath JK (1987) Transforming growth factor modifies the expression of collagenase and metalloproteinase inhibitor. EMBO J 6: 1899-1904
8. Ignotz RA, Massangue J (1987) Cell adhesion protein receptors as targets for transforming growth factor-β action. Cell 51: 189-197
9. Katz ED, Dong MW (1990) Rapid analysis and purification of polymerase chain reaction products by high-performance liquid chromatography. Biotechniques 8: 546-555
10. Kehrl JH, Wakefield LM, Roberts AB, Jakowlew S, Alvarez-Mon M, Derynck R, Sporn MB, Fauci AS (1986) Production of transforming growth factor β by human T lymphocytes and its potential role in the regulation of T cell growth. J Exp Med 163: 1037-1050
11. Kuwano Y. Nakanishi O, Nabeshima Y, Tanaka T, Ogata K (1985) Molecular cloning and nucleotide sequence of DNA complementary to rat ribosomal protein S26 messenger RNA. J Biochem 97: 983-992
12. Laiho M, Saksela O, Keski OJ (1987) Transforming growth factor-β induction of type-1 plasminogen activator inhibitor. Pericellular deposition and sensitivity to exogenase urokinase. J Biol Chem 262: 17467-17474
13. Land W (1989) Kidney transplantation - state of the art. Transplant Proc 21: 1425
14. Lawrence WT, Norton JA, Sporn MB, Gorschboth C, Grottendorst GR (1986) The reversal of an Adriamycin induced healing impairment with chemoattractants and growth factors. Ann Surg 203: 142-147
15. Lefebvre B, Formstecher P, Lefebvre P (1995) Improvement of the gene splice overlap (SOE) method. Biotechniques 19: 186-187
16. Majesky MW, Lindner V, Twardzik DR, Schwartz SM, Reidy MA (1991) Production of transforming growth factor β1 during repair of arterial injury. J Clin Invest 88: 904-910
17. Mennander A, Tiisala S, Halttunen J, Yilmaz S, Paavonen T, Hayry P (1991) Chronic rejection in rat aortic allografts - an experimental model for transplant arteriosclerosis. Art and Thromb 11: 671-680
18. Nabel EG, Shum L, Pompili VJ, Yang Z, San H, Shu HB, Liptay S, Gold L, Gordon D, Derynck R, Nabel GJ (1993) Direct transfer of transforming growth factor β1 gene into arteries stimulates fibrocellular hyperplasia. Proc Natl Acad Sci USA 90: 10759-10763
19. Nikol S, Isner JM, Pickering JG, Kearney M, Leclerc G, Weir L (1992) Expression of transforming growth factor-β1 is increased in human vascular restenosis lesions. J Clin Invest 90: 1582-1592
20. Nilsen-Hamilton M (1990) Current topics in development biology. 24 Academic Press, New York, pp 95-136
21. Qian SW, Kondaiah P, Roberts A, Sporn MB (1990) cDNA cloning by PCR of rat transforming growth factor β-1. Nucleic Acids Res 18: 3059
22. Qin L, Chavin KD, Ding Y, Woodward JE, Favaro JP, Lin J, Bromberg JS (1994) Gene transfer for transplantation. Prolongation of allograft survival with transforming growth factor-beta 1. Ann Surg 220: 508-518
23. Raju GP, Belland SE, Eisen HJ (1994) Prolongation of cardiac allograft survival with transforming growth factor-β1 in rats. Transplantation 58: 392-396
24. Roberts AB, Sporn MB, Assosian RK, Smith JM, Roche NS, Wakefield LM, Heine UI, Liotta LA, Falanga V, Kehrl JH, Fauci AF (1986) Transforming growth factor β: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci USA 83: 4167-4171
25. Ruoslahti E, Yamaguchi Y (1991) Proteoglycans as modulators of growth factor activities. Cell 64: 867-869
26. Ruscetti FW, Palladino MA (1991) Transforming growth factor-β and the immune system. Progress in Growth Factor Research Great Britain 3: 159-175
27. Sarzani R, Brecher P, Chobanian AV (1989) Growth factor expression in aorta of normotensive and hypertensive rats. J Clin Invest 83: 1404-1408
28. Stoltenberg RL, Geraghty JG, Steele DM, Kennedy E, Hullett DA, Sollinger HW (1995) Inhibition of intimal hyperplasia in rat aortic allografts with cyclosporin. Transplantation 60: 993-998
29. Tsunawaki S, Sporn MB, Ding A, Nathan C (1988) Deactivation of macrophages by transforming growth factor-β. Nature 334: 260-262
30. Wahl SM (1992) Transforming growth factor beta (TGFβ) in inflammation: a cause and a cure. J Clin Immunol 12: 61-74
31. Wahl SM (1994) Transforming growth factor β: The good, the bad, and the ugly. J Exp Med 180: 1587-1590
32. Wahl SM, McCartney-Francis N, Allen JB, Dougherty EB, Dougherty SF (1990) Macrophage production of TGF-β and regulation by TGF-β. Ann NY Acad Sci 593: 188-196
33. Wahl SM, McCartney-French N, Mergenhan SE (1989) Inflammatory and immunomodulatory roles of TGF-β. Immunol Today 10: 258-260
34. Wallick SC, Figari IS, Morris RE, Levinson AD, Palladino MA (1990) Immuno-regulatory role of transforming growth factor-β (TGFβ) in development of killer cells: comparison of active and latent TGF-β1. J Exp Med 172: 1777-1784
35. Waltenberger J, Miyazono K, Funa K, Wanders A, Fellstrom B, Heldin CH (1993) Transforming growth factor-β and organ transplantation. Transplant Proc 25: 2038-2040
36. Waltenberger J, Wanders A, Fellstrom B, Miyazono K, Heldin CH (1993) Induction of transforming growth factor-β during cardiac allograft rejection. J Immunol 151: 1147-1157
37. Warwick-Davies J, Lowire DB, Cole PJ (1995) Selective deactivation of human monocyte functions by TGF-β. J Immunol 155: 3186-3193
38. Wolf YG, Rasmussen LM, Ruoslahti E (1994) Antibodies against transforming growth factor-β1 suppresses intimal hyperplasia in a rat model. J Clin Invest 93: 1172-1178