Microbial conversion of methyl- and methoxy- substituted derivatives of SH indolo[2,3-b] guinoline as a method of developing novel cytotoxic agents

Anticancer Research

Volumn 19, Issue 4 B, 1999, Pages 3333-3342

  Osiadacz, Jarosław ^a   Kaczmarek, Łukasz ^b   Opolski, Adam ^a   Wietrzyk, Joanna ^a   Marcinkowska, Ewa ^a   Biernacka, Katarzyna ^a   Radzikowski, Czesław ^a   Jon, Marek ^c   Peczyńska Czoch, Wanda ^d  

^a INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

^b INDUSTRIAL CHEMISTRY RESEARCH INSTITUTE   (Poland)

^c UNIVERSITY OF WROC AW   (Poland)

^d WROCLAW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Ceruloplasmin; Cunninghamella elegans; Cytotoxic agents; Indolo 2,3 b quinoline; Laccase; Microbial model of mammalian metabolism; P 450

Indexed keywords

ANTINEOPLASTIC AGENT; CERULOPLASMIN; CYTOTOXIC AGENT; INDOLOQUINOLINE DERIVATIVE; LACCASE; OXIDOREDUCTASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOTRANSFORMATION; COLON ADENOCARCINOMA; CONTROLLED STUDY; CUNNINGHAMELLA; DEMETHYLATION; DRUG CYTOTOXICITY; DRUG HYDROXYLATION; DRUG METABOLISM; LIVER MICROSOME METABOLISM; LUNG CARCINOMA; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOTRANSFORMATION; CERULOPLASMIN; DRUG DESIGN; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICROSOMES, LIVER; QUINOLINES; RATS;

EID: 0033427991     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

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