Development and biopharmaceutical evaluation of controlled release tablets of metformin hydrochloride using dissolution medium with gradual pH variation;Desenvolvimento e avaliacao biofarmacotecnica de comprimidos de liberacao controlada de cloridrato de metformina empregando meio de dissolucao com variacao gradual de pH

Revista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences

Volumn 35, Issue 1, 1999, Pages 107-109

  De Jesus, J ^a   De Pinho, R G ^a   Storpirtis, S ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Biopharmaceutics; Controlled release; Dissolution; Metformin hydrochlorid; PH gradual variation; Tablets

Indexed keywords

AEROSIL; GELATIN; HYDROXYPROPYLMETHYLCELLULOSE; MAGNESIUM STEARATE; MANNITOL; METFORMIN; POVIDONE; STEARIC ACID;

ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; MATHEMATICAL COMPUTING; PH; TABLET; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0033427913     PISSN: 15169332     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)