3-Hydroxyanthranilic acid accumulation following administration of the 3-hydroxyanthranilic acid 3,4-dioxygenase inhibitor NCR-631

European Journal of Pharmacology

Volumn 386, Issue 1, 1999, Pages 15-24

  Fornstedt Wallin, Bodil ^a   Lundström, Jan ^b   Fredriksson, Göran ^c   Schwarcz, Robert ^d   Luthman, Johan ^a  

^a Preclin RD Astra Arcus S 151 85 ^*  (Sweden)

^b Research Drug Metabolism and Pharmacokinetics   (Sweden)

^c Bioanalysis   (Sweden)

^d MARYLAND PSYCHIATRIC RESEARCH CENTER   (United States)

Author keywords

(Rat); 3 Hydroxyanthranilic acid; Brain; Inhibitor; Kynurenine; Plasma

Indexed keywords

3 HYDROXYANTHRANILIC ACID; 3 HYDROXYANTHRANILIC ACID 3,4 DIOXYGENASE INHIBITOR; 5 HYDROXYINDOLEACETIC ACID; EXCITOTOXIN; KYNURENINE; NCR 631; OXYGENASE INHIBITOR; QUINOLINIC ACID; SEROTONIN; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG HALF LIFE; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; TRYPTOPHAN METABOLISM;

3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE; 3-HYDROXYANTHRANILIC ACID; ANIMALS; BRAIN; DIOXYGENASES; ENZYME INHIBITORS; HYDROXYINDOLEACETIC ACID; KYNURENIC ACID; MALE; OXYGENASES; QUINOLINIC ACID; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; TRYPTOPHAN;

EID: 0033410219     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00683-4     Document Type: Article

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