Renal and cardiovascular role of the neuropeptide Y Y1 receptor in ischaemic heart failure rats

Journal of Pharmacy and Pharmacology

Volumn 51, Issue 11, 1999, Pages 1257-1265

  Zhao, Xiao He ^a   Sun, Xiang Ying ^a   Bergdahl, Anders ^b   Edvinsson, Lars ^b   Hedner, Thomas ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

NALPHA (DIPHENYLACETYL) N (4 HYDROXYBENZYL) DEXTRO ARGININAMIDE; NEUROPEPTIDE Y; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; NEUROPEPTIDE Y1 RECEPTOR; NORADRENALIN; POTASSIUM; SODIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BLOOD PRESSURE; BOLUS INJECTION; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; DOSE RESPONSE; HEART RATE; ISCHEMIC HEART DISEASE; KIDNEY FUNCTION; MALE; NERVE STIMULATION; NONHUMAN; POTASSIUM URINE LEVEL; PREGANGLIONIC NERVE; PRESSOR RESPONSE; RAT; RECEPTOR DOWN REGULATION; RENAL ARTERY; SODIUM URINE LEVEL; SYMPATHETIC NERVE; URINE VOLUME;

EID: 0033406271     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357991776994     Document Type: Article

References (20)

1. Bischoff, A., Michael, M. C. (1998) Renal effects of neuropeptide Y. Pflugers Arch. 435: 443-453
2. 5 are involved in the renal effects of neuropeptide Y. Br. J. Pharmacol. 120: 1335-1343
3. Dahlöf, C., Dahlöf, P., Lundberg, J. M. (1985) Neuropeptide Y (NPY): enhancement of blood pressure increases upon alpha-adreno receptor activation and direct pressor effects in pithed rats. Eur. J. Pharmacol. 109: 289-292
4. Edvinsson, L., Ekblad, E., Håkanson, R., Wahlestedt, C. (1984) Neuropeptide Y potentiates the effect of various vasoconstrictor agents on rabbit blood vessels. Br. J. Pharmacol. 83: 519-525
5. Edvinsson, L., Ekman, R., Hedner, P., Valdemarsson, S. (1990) Congestive heart failure: involvement of perivascular peptides reflecting activity in sympathetic, parasympathetic and afferent fibers. Eur. J. Clin. Invest. 20: 85-89
6. Ekblad, E., Edvinsson, L., Wahlestedt, C., Uddman, R., Håkanson, R. (1984) Neuropeptide Y co-exists and cooperates with noradrenaline in perivascular fibers. Regul. Pept. 8: 225-235
7. Erlinge, D., Yoo, H., Edvinsson, L., Reis, D. J., Wahlestedt, C. (1993) Mitogenic effects of ATP on vascular smooth muscle cells vs. other growth factors and sympathetic cotransmitters. Am. J. Physiol. 265: H1089-H1097
8. Feng, Q. P. (1993) Sympathetic Regulation of Cardiovascular and Renal Function in Rats with Experimental Congestive Heart Failure. Thesis, Göteborg University, Sweden, pp 1-86
9. Grundemar, L., Håkanson, R. (1994) Neuropeptide Y effector systems: perspectives for drug development. Trends Pharmacol. Sci. 15: 153-159
10. Kasakov, L., Ellis, J., Kirkpatick, K., Milner, P., Burnstock, G. (1988) Direct evidence for concomitant release of noradrenaline, adenosine 5′-triphosphate and neuropeptide Y from sympathetic nerves supplying the guinea-pig vas deferens. J. Auton. Nerv. Syst. 22: 75-78
11. Lacroix, J. S., Stjärne, P., Änggård, A., Lundberg, J. M. (1989) Sympathetic vascular control of the pig nasal mucous (III): co-release of noradrenaline and neuropeptide Y. Acta. Physiol. Scand. 135: 17-28
12. Leys, K., Schachter, M., Sever, P. (1987) Auto radiographic localisation of neuropeptide Y receptors in rabbit kidney: comparison with rat, guinea-pig and human. Eur. J. Pharmacol. 134: 233-237
13. Linton-Dahlöf, P. (1989) Modulatory interactions of neuropeptide Y (NPY) on sympathetic neurotransmission. Acta. Physiol. Scand. 137 (Suppl. 586): 1-85
14. Lundberg, J. M., Terenius, L., Hökfelt, L., Hökfelt, T., Goldstein, M. (1983) High levels of neuropeptide Y (NPY) in peripheral noradrenergic neurones in various mammals including man. Neurosci. Lett. 42: 167-172
15. Lundberg, J. M., Rudehill, A., Sollevi, A., Hamberger, B. (1989) Evidence for co-transmitter role of neuropeptide Y in the pig spleen. Br. J. Pharmacol. 96: 675-687
16. Sun, X. Y., Dahlöf, C., Edvinsson, L., Hedner, T. (1991) D-myo-inositol-triphosphate is a selective antagonist of neuropeptide Y-induced pressor response in the pithed rat. Eur. J. Pharmacol. 204: 281-286
17. Sun, X. Y., Feng, Q. P., Zhao, X. H., Edvinsson, L., Hedner, T. (1995) Cardiovascular and renal effects of alpha-trinositol in ischaemic heart failure rats. Life Sci. 57: 1197-1211
18. Torres, G., Bitran, M., Huidobro-Toro, J. P. (1992) Co-release of neuropeptide Y (NPY) and noradrenaline from sympathetic nerve terminals supplying the rat vas deferens; influence of calcium and the stimulation intensity. Neurosci. Lett. 148: 39-42
19. Valdemarsson, S., Bergdahl, A., Edvinsson, L. (1994) Relationships between plasma levels of catecholamines and neuropeptides and the survival time in patients with congestive heart failure. J. Intern. Med. 235: 595-601
20. Zukowska-Grojec, Z., Karwatowska-Prokopczuk, E., Rose, W., Rone, J., Movafagh, S., Ji, H., Yeh, Y., Chen, W. T., Kleinman, H. K., Grouzmann, E., Grant, D. S. (1998) Neuropeptide Y: a novel angiogenic factor from the sympathetic nerves and endothelium. Circ. Res. 83: 187-195