The silent T1317C mutation of methylenetetrahydrofolate reductase should not interfere with Mboll restriction isotyping of the reported A1298C mutation

Molecular Genetics and Metabolism

Volumn 68, Issue 4, 1999, Pages 511-512

  Donnelly, J G ^a   Sibani, S ^a   Leclerc, D ^a   Weisberg, I ^a   Rozen, R ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2);

AMINO ACID SUBSTITUTION; GENE FREQUENCY; GENE SEQUENCE; GENOTYPE; LETTER; MEDICAL LITERATURE; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; RESTRICTION MAPPING;

EID: 0033401846     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1006/mgme.1999.2944     Document Type: Editorial

References (2)

1. I Weisberg P Tran B Christensen S Sibani R Rozen A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity Molec Genet Metab 64 1998 169 172
2. N MJ van der Put G Fons E MB Stevens J AM Smeitink F JM Trijbels T KAB Eskes LP van den Heuvel HJ Blom A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neural-tube defects Am J Hum Genet 62 1998 1044 1051