Synthesis of the nanomolar photoaffinity GABA(B) receptor ligand CGP 71872 reveals diversity in the tissue distribution of GABA(B) receptor forms

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 12, 1999, Pages 2697-2704

  Belley, Michel ^a   Sullivan, Richard ^a   Reeves, Austin ^b   Evans, Jilly ^a   O'Neill, Gary ^a   Ng, Gordon Y K ^a  

^a Biochemistry and Molecular Biology   (Canada)

^b NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

CGP 71872; GABA; GABA(B) receptor; Photoaffinity labeling

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; BACLOFEN; CGP 71872; GLUTAMIC ACID; IODINE 125; ISOPROTEIN; SACLOFEN; UNCLASSIFIED DRUG;

ADRENAL GLAND; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN MEMBRANE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOG; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HYPOPHYSIS; KIDNEY; LIGAND BINDING; LIVER; NONHUMAN; PHOTOAFFINITY LABELING; PROSTATE; PROTEIN EXPRESSION; RADIOIODINATION; RAT; SPINAL CORD; SPLEEN; STEREOSPECIFICITY; STOMACH; TESTIS; TISSUE DISTRIBUTION;

AFFINITY LABELS; AMINO ACID SEQUENCE; ANIMALS; AZIDES; BINDING, COMPETITIVE; DOGS; FEMALE; GABA ANTAGONISTS; IODINE RADIOISOTOPES; LIGANDS; MALE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; ORGANOPHOSPHORUS COMPOUNDS; RATS; RECEPTORS, GABA-B; TISSUE DISTRIBUTION;

CANIS FAMILIARIS;

EID: 0033400772     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00214-X     Document Type: Article

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