Contractility and endothelium-dependent relaxation of resistance vessels in polycystic kidney disease rats

Journal of Vascular Research

Volumn 36, Issue 6, 1999, Pages 502-509

  Wang, Dan ^a   Iversen, Jens ^b   Strandgaard, Svend ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NONE

Author keywords

Acetylcholine; Autosomal dominant polycystic kidney disease; Contractility; Endothelium dependent relaxation; Han:SPRD rat; Hypertension; Nitric oxide; Resistance vessels

Indexed keywords

ACETYLCHOLINE; LINSIDOMINE; N(G) NITROARGININE METHYL ESTER; NORADRENALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BLOOD VESSEL REACTIVITY; BLOOD VESSEL TONE; BLOOD VESSEL WALL; CONTROLLED STUDY; FEMALE; HETEROZYGOTE; HYPERTENSION; KIDNEY POLYCYSTIC DISEASE; MALE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; RESISTANCE BLOOD VESSEL; VASCULAR DISEASE; VASCULAR ENDOTHELIUM; VASODILATATION;

EID: 0033400484     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000025693     Document Type: Article

References (27)

1. Biagini A, Maffei S, Baroni M: Familiar clustering of aortic dissection in polycystic kidney disease. Am J Cardiol 1993;72:741-742.
2. Griffin MD, Torres VE, Grande JP, Kumar R: Vascular expression of polycystin in ADPKD and control subjects (abstract). J Am Soc Nephrol 1996;7:1613.
3. Grantham JJ, Geiser JL, Evan AP: Cyst formation and growth in autosomal dominant polycystic kidney disease. Kidney Int 1987;31: 1145-1152.
4. Van Adelsberg JS, Frank D: The PKD1 gene produces a developmentally regulated protein in mesenchyme and vasculature (see comments). Nat Med 1995;1:359-364.
5. Wang D, Strandgaard S: The pathogenesis of hypertension in autosomal dominant polycystic kidney disease (review). J Hypertens 1997; 15:925-933.
6. Iversen J, Frandsen H, Nargaard N, Strandgaard S: Sympathetic nervous activity in adult polycystic kidney disease (abstract). Hypertension 1996;28:692.
7. Biller DS, Dibartola SP, Eaton KA, Pflueger S, Wellman ML, Radin MJ: Inheritance of polycystic kidney disease in Persian cats. J Hered 1996;87:1-15.
8. Eaton KA, Biller DS, DiBartola SP, Radin MJ, Wellman ML: Autosomal dominant polycystic kidney disease in Persian and Persian-cross cats. Vet Pathol 1997;34:117-126.
9. Cowley BD Jr, Gudapaty S, Kraybill AL, Barash BD, Harding MA, Calvet JP, Gattone VH 2d: Autosomal-dominant polycystic kidney disease in the rat. Kidney Int 1993;43:522-534.
10. Schafer K, Gretz N, Bader M, Oberbaumer I, Eckhardt KU, Kriz W, Bachmann S: Characterization of the Han:SPRD rat model for hereditary polycystic kidney disease. Kidney Int 1994;46:134-152.
11. Luscher TF, Boulangern CM, Dohi Y, Yang Z: Endothelium-derived contracting factor. Hypertension 1992;19:117-130.
12. Dohi Y, Criscioni L, Luscher TF: Renovascular hypertension impairs formation of endothelium-derived relaxing factors and sensitivity to endothelin-1 in small arteries. Br J Pharmacol 1991;104:349-354.
13. Rizzoni D, Porteri E, Castellano M, Bettoni G, Muiesan ML, Muiesan P, Guilini SM, Agabiti-Rosei E: Vascular hypertrophy and remodeling in secondary hypertension. Hypertension 1996;28:785-790.
14. Taddei S, Salvetti A: Pathogenic factors in hypertension endothelial factors. Clin Exp Hypertens 1996;18:323-335.
15. McNally PG, Watt PAC, Rimmer T, Burden AC, Hearnshaw JR, Thurston H: Impaired contraction and endothelium-dependent relaxation in isolated resistance vessels from patients with insulin-dependent diabetes mellitus. Clin Sci 1994;87:31-36.
16. Heygate KM, Lawrence IG, Bennett MA, Thurston H: Impaired endothelium-dependent relaxation in isolated resistance arteries of spontaneously diabetic rats. Br J Pharmacol 1995;116:3251-3259.
17. Mulvany MJ, Halpern W: Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ Res 1977;41:19-26.
18. Schiffrin EL, Deng LY, Larochelle P: Effect of endothelin upon small subcutaneous small arteries of mild essential hypertensive patients. J Hypertens 1992;10:437-444.
19. Patel DJ, Fry DL: The elastic symmetry of arterial segments in dogs. Circ Res 1969;24: 1-8.
20. Mulvany MJ, Halpern W: Mechanical properties of vascular smooth muscle cells in situ. Nature 1976;260:617-619.
21. Griffin MD, Torres VE, Grande JP, Kumar R: Vascular expression of polycystin. J Am Soc Nephrol 1997;8:616-626.
22. Zanchi A, Aubert JF, Brunner HR, Waeber B: Vascular acetylcholine response during chronic NO synthase inhibition: In vivo versus in vitro. Cardiovasc Res 1995;30:122-129.
23. Richard V, Gosgnach M, La-Rochelle CD, Giudicelli JF, Berdeaux A: The L-arginine-nitric oxide pathway in the canine femoral vascular bed: In vitro and in vivo experiments. Fund Clin Pharmacol 1991;5:777-788.
24. Kahonen M, Makynen H, Wu X, Arvola P, Porsti I: Endothelial function in spontaneously hypertensive rats: Influence of quinapril treatment. Br J Pharmacol 1995;115:859-867.
25. Van de Voorde J, Leusen I: Endothelium-dependent and -independent relaxation of aortic rings from hypertensive rats. Am J Physiol 1986;250:H711-H717.
26. Wang D, Iversen J, Strandgaard S: Nitric oxide-mediated changes in the relaxation of resistance vessel in patients with autosomal dominant polycystic kidney disease (ADPKD) (abstract). J Am Soc Nephrol 1997;8:383A.
27. Torres VE, Bengal RJ, Nickander KK, Grande JP, Low PA: Renal concentration of α-tocopherol: Dependence on gender and lack of effect on polycystic kidney disease in Han:SPRD rats. Am J Kidney Dis 1998;31:687-693.