QSAR studies on antimalarial activities of 2-phenyl-4-quinoline-carbinolamines

Polish Journal of Pharmacology

Volumn 51, Issue 6, 1999, Pages 517-523

  Agrawal, Vijay K ^a   Sinha, Sangeeta ^a   Bano, Shahnaz ^a   Khadikar, Padmakar V ^b  

^a A P S UNIVERSITY   (India)

^b Laxmi Pest and Fumigation Pvt Ltd   (India)

Author keywords

Antimalarial agents; Carbinolamine derivatives; QSAR studies

Indexed keywords

2 PHENYL 4 QUINOLINE CARBINOLAMINE; ANTIMALARIAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; MOUSE; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANTIMALARIALS; ELECTRONS; MOLECULAR CONFORMATION; QUINOLINES;

EID: 0033400199     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Bhattacharjee A. K., Karle J. M.: Molecular electronic properties of a series of 4-quinolinecarbinolamines define antimalarial activity profile. J. Med. Chem., 1996, 29, 4612-4629.
2. Oaks S. C., Mitchell V. S., Pearson G. W., Carpenter C.C.: Malaria Obstacles and Opportunities. National Academic Press, Washington, DC, 1991, 144-168.
3. Odecola A. M., Omitowoju G. C., Gerena L., Kyle D. K., Milhous W. K., Sowunnei A., Salako L. A.: Reversal of mefloquine resistance with penfluridol in isolates of plasmodium falciparum from South West Nigeria. Trans. Roy. Soc. Trop. Med. Hyg., 1991, 87, 81-83.
4. Osdene T. S., Russell P. B., Rane L.: 2,4,7-Triamino-6-ortho-substituted arylpteridines. a new series of potent antimalarial agents. J. Med. Chem., 1967, 10, 431-436.
5. Pogliqni L.: Amino Acids, 1994, 6, 141.
6. Sweeney T. R.: In: A Survey of Compounds from Antimalarial Drug Development Programme of the US Army Medical Research and Development Command. Water Reed Army Institute of Research, Washington, DC, 1991, 1-316.
7. Wissner A.: HMO Version 1.1: Huckel Molecular Orbital Program for the Macintosh, Tetrahedron Computer Methodology, Tetrahedron Comput. Methodol., 1990, 3, 63-71.