Histomorphometry and quantification of nucleolar organizer regions in bovine thyroid containing methylthiouracil residues

Veterinary Pathology

Volumn 36, Issue 6, 1999, Pages 574-582

  Serakides, R ^a   Nunes, V A ^b   Santos, R L ^b   Cassali, G D ^b   Neto, P P Costa ^b  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b NONE

Author keywords

AgNOR; Bovine; Histomorphometry; Methylthiouracil; Thyroid

Indexed keywords

METHYLTHIOURACIL;

ADENOMATOSIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATTLE; CELL PROLIFERATION; CHROMOSOME NOR; COLLOID; CONTROLLED STUDY; MORPHOMETRICS; NONHUMAN; THYROID FOLLICLE; THYROID GLAND; THYROID HYPERPLASIA;

EID: 0033398958     PISSN: 03009858     EISSN: None     Source Type: Journal    
DOI: 10.1354/vp.36-6-574     Document Type: Article

References (31)

1. Aubele M, Biesterfield S, Derenzini M, Hufnagl P, Martin H, Öfner D, Ploton D, Rüschoff J: Guidelines of AgNOR quantitation. Zentralbl Pathol 40:107-108, 1994
2. Cochran WG, Cox GM: Experimental Designs, 2nd ed., pp. 1-611. John Wiley & Sons, New York, NY, 1957
3. De Brabander HF, Verbeke R: Detection of antithyroid residues in meat and some organs of slaughtered animals. J Chromatogr 108:141-151, 1975
4. Denef JF, Cordier AC, Mesquita M, Haumont S: The influence of fixation procedure, embedding medium and section thickness on morphometric data in thyroid gland. Histochemistry 63:163-171, 1979
5. Dumont JE, Lamy F, Roger P, Maenhaut C: Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors. Physiol Rev 72:667-697, 1992
6. Gaitan E: Goitrogens in food and water. Annu Rev Nutr 10:21-39, 1990
7. Griem W: Pathologisch-histologische Veränderungen von Schilddrüsen bei rindern und kaninchen nach verfütterung von methylthiouracil. Berl Munch Tierarztl Wochenschr 86:50-56, 1973
8. Haynes RC Jr Tireóide e drogas antitireóideas. In: As Bases Farmacológicas da Terapêutica, ed. Gilman AG, Rail TW, and Nies AS, 8th ed., pp. 906-920. Guanabara Koogan, Rio de Janeiro, Brazil, 1991
9. Ingbar SH: The thyroid gland. In: Textbook of Endocrinology, ed. Wilson JD and Foster DW, 7th ed., pp. 682-815. WB Saunders, London, England, 1985
10. Kanematsu E, Matsui H, Deguchi T, Yamamoto O, Korematsu M, Kobayashi A, Nezasa SI, Yamamoto N, Takeuchi T, Tanaka T, Kawada Y: Significance of AgNOR counts for distinguishing carcinoma from adenoma and hyperplasia in parathyroid gland. Hum Pathol 28:421-427, 1997
11. Luna LG: Manual of Histologic Staining Methods of the Armed Forces Institute of Pathology, 3rd ed., p. 258. McGraw Hill, New York, NY, 1968
12. Luvizotto MCR: Aspectos Morfológicos. Morfométricos e Funcionais da Tireóide e das Paratireóides na "Doença Periodontal" Dos Bovinos. Escola de Veterinária da UFMG, Belo Horizonte, Brazil, 1984
13. Moretti G, Amici M, Cammarata P, Fracassi F: Identification of thyrostatic drug residues in animal thyroids by high-performance thin layer chromatography and fluorescence reaction detection. J Chromatogr 442:459-463, 1988
14. Nairn ER, Crocker J, Mcgovern J: Limited value of AgNOR enumeration in assessment of thyroid neoplasms. J Clin Pathol 41:1136, 1988
15. Nyberg JA: Morphological and clinico-chemical studies of thyroid function in lactating cattle. Acta Vet Scand 31:1-120, 1970
16. Palliola E, Moretti G, Nanni A, Amici M, Rossi C: Valutazione degli esami istologico, ponderale e chimico sulle tiroidi dei bovini quali elementi per il controllo del trattamento illegale con tireostatici. Ann Ist Super Sanita 23:129-134, 1987
17. Ploton D: Structure and molecular organization of the nucleolus. Zentralbl Pathol 140:3-6, 1994
18. Ploton D, Menager M, Jeannesson P, Himber G, Pigeon F, Adnet JJ: Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region al the optical level. Histochemical J 18:5-14, 1986
19. Pochard MF: Problems liés a l'utilisation des thyréostatiques en élevage bovin. Bull Lab Vet 13:33-42, 1984
20. Pottie G: Verwendbarkeit der histologischen schilddrüsenuntersuchung bei erwachsenen rindern zur ermittlung des mißbrauches von thyreostatica. Fleischwirtsch 59:248-250, 1979
21. Romaldini JH, Bianco AC: Hormônios tireoidianos. In: Farmacologia Integrada. Fundamentos Farmacológicos da Terapêutica, ed. Valle LBS, pp. 895-909. Atheneu, Rio de Janeiro, Brazil, 1991
22. Roussel P, Hernandez-Verdum D: Identification of AgNOR proteins, markers of proliferation related to ribosomal gene activity. Exp Cell Res 214:465-472, 1994
23. Ruckebusch Y, Phaneuf LP, Dunlop R: Physiology of Small and Large Animals, pp. 1-672. BC Decker, Philadelphia, PA, 1991
24. Rüschoff J Plate KH, Contractor H, Kern S, Zimmer-mann R, Thomas C: Evaluation of nucleolar organizer regions (NORs) by automatic image analysis: a contribution to standardization. J Pathol 161:113-118, 1990
25. Shiro T, Seki T, Naitoh Y, Inoue K, Okamura A: A correlation of argyrophilic nucleolar organizer regions with stages of hepatocellular carcinoma. Cancer 71:44-49, 1992
26. Studer H, Gerber H: Multinodular goiter. In: Endocrinology, ed. Degroot LJ, 3rd ed., pp. 769-781. WB Saunders, London, England, 1995
27. Tood GC: Induction and reversibility of thyroid prolif-erative changes in rats given an antithyroid compound. Vet Pathol 23:110-117, 1986
28. Trerè D: Ag-NOR quantification in tumor pathology: what is actually evaluated? J Clin Pathol 46:189, 1993
29. Underwood JC, Giri DD: Nucleolar organizer regions as diagnostic discriminants for malignancy. J Pathol 155:95-96, 1988
30. Uotila U, Kannas O: Quantitative histological method of determining the proportions of the principal components of thyroid tissue. Acta Endocrinol 11:49-60, 1952
31. Winter H, Massey JC: Postmortem identification of thyrostatic drugs. Aust Vet Assoc Year 245-247, 1981