Are older patients with mechanical heart valves at increased risk?

Annals of Thoracic Surgery

Volumn 68, Issue 6, 1999, Pages 2169-2172

  Masters, Roy G ^a   Semelhago, Lloyd C ^a   Pipe, Andrew L ^a   Keon, Wilbert J ^a  

^a UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AORTA VALVE REPLACEMENT; ARTICLE; BLEEDING; FEMALE; HEART VALVE PROSTHESIS; HEART VALVE REPLACEMENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MITRAL VALVE REPLACEMENT; PRIORITY JOURNAL; RISK ASSESSMENT; THROMBOEMBOLISM;

AGE FACTORS; AGED; ANTICOAGULANTS; AORTIC VALVE; HEART VALVE PROSTHESIS IMPLANTATION; HEMORRHAGE; HUMANS; MALE; MIDDLE AGED; MITRAL VALVE; PROSPECTIVE STUDIES; RISK FACTORS; THROMBOEMBOLISM; WARFARIN;

EID: 0033396839     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4975(99)00826-7     Document Type: Article

References (12)

1. Arom K.V., Emery R.W., Nicoloff D.M., Petersen R.J. Anticoagulant related complications in elderly patients with St. Jude mechanical valve prostheses. J Heart Valve Dis. 5:1996;505-510.
2. Jamieson W.R.E. Mechanical and bioprosthetic aortic valve replacement. Edmunds L.H. Jr. Cardiac surgery in the adult. 1997;859-909 McGraw-Hill, New York.
3. Stein P.D., Alpert J.S., Copeland J., Dalen J.E., Goldman S., Turpie A.G.G. Antithrombotic therapy in patients with mechanical and biological prosthetic heart valves. Chest. 102:(suppl):1992;445-454.
4. Edmunds L.H. Jr, Clark R.E., Cohn L.H., Miller D.C., Weisel R.D. Guidelines for reporting morbidity and mortality after cardiac valvular operations. Ann Thorac Surg. 62:1996;932-935.
5. Landefeld C.S., Goldman L. Major bleeding in outpatients treated with warfarin incidence and prediction by factors known at the start of outpatient therapy . Am J Med. 87:1989;144-152.
6. Cannegieter S.C., Rosenthal F.R., Wintzen A.R., van der Meer F.J., Vandenbroucke J.P., Briet E. Optimal oral anticoagulant therapy in patients with mechanical heart valves. N Engl J Med. 333:1996;11-17.
7. Bleeding during antithrombotic therapy in patients with atrial fibrillation. Arch Intern Med. 156:1996;409-416.
8. Warfarin versus aspirin for prevention of thromboembolism in atrial fibrillation. Lancet. 343:1994;687-691.
9. Van der Meer F.J., Rosendaal F.R., Vandenbroucke J.P., Briet E. Bleeding complications in oral anticoagulant therapy. An analysis of risk factors. Arch Intern Med. 153:1993;1557-1562.
10. Forfar J.C. A 7-year analysis of haemorrhage in patients on long-term anticoagulant treatment. Br Heart J. 42:1979;128-132.
11. Lundstrom T., Ryden L. Haemorrhagic and thromboembolic complications in patients with atrial fibrillation on anticoagulant prophylaxis. J Intern Med. 225:1989;137-142.
12. Fihn S.D., Callahan C.M., Martin D.C., McDonell M.B., Henikoff J.G., White R.H. The risk for and severity of bleeding complications in elderly patients treated with warfarin. Ann Intern Med. 124:1996;970-979.