Apoptosis and catastrophic cell death in benzo[a]pyrene-transformed human breast epithelial cells

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 431, Issue 1, 1999, Pages 133-139

  Barbisan, Luís Fernando ^a   Mello, Maria Luíza S ^a   Russo, Jose ^b   De Campos Vidal, Benedicto ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

Apoptosis; Benzo a pyrene; c Ha ras; Human breast epithelial cells; Mitotic death

Indexed keywords

BENZO[A]PYRENE;

APOPTOSIS; ARTICLE; BREAST EPITHELIUM; CELL DEATH; CELL TRANSFORMATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; MICRONUCLEUS; MULTINUCLEAR CELL; ONCOGENE C H RAS; PRIORITY JOURNAL;

APOPTOSIS; BENZO(A)PYRENE; BREAST; CELL DEATH; CELL LINE, TRANSFORMED; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; EPITHELIAL CELLS; GENES, RAS; HUMANS; MITOSIS; MITOTIC INDEX; TRANSFECTION;

EID: 0033395194     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(99)00193-1     Document Type: Article

References (26)

1. Raff M.C. Social controls on cell survival and cell death. Nature. 356:1992;397-400.
2. Hartwell L.H., Kastan M.B. Cell cycle control and cancer. Science. 266:1994;1821-1828.
3. Wyllie A.H., Kerr J.F.R., Currie A.R. Cell death: the significance of apoptosis. Int. Rev. Cytol. 68:1980;251-306.
4. Wyllie A.H. Glucocorticoid induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature. 284:1980;555-556.
5. Arends M.J., Morris R.G., Wyllie A.H. Apoptosis: the role of the endonuclease. Am. J. Pathol. 136:1990;593-608.
6. Bursh W., Paff S., Putz B., Barthel G., Schulte-Hermann R. Determination of the length of the histological stages of apoptosis in normal liver and altered hepatic foci of rats. Carcinogenesis. 11:1990;847-853.
7. Chang W.P., Little J.B. Delayed reproductive death in X-irradiated Chinese hamster ovary cells. Int. J. Radiat. Biol. 60:1991;483-496.
8. Tounekti O., Pron G., Belehradek J. Jr., Mir L.M. Bleomycin, an apoptosis-mimetic drug that induces two types of cell death depending on the number of molecules internalized. Cancer Res. 53:1993;5462-5469.
9. Lock R.B., Galperina O.V., Feldhoff R.C., Rhodes L.J. Concentration-dependent differences in the mechanisms by which caffeine potentiates etoposide cytotoxicity in HeLa cells. Cancer Res. 54:1994;4933-4939.
10. Calaf G., Russo J. Transformation of human breast epithelial cells by chemical carcinogens. Carcinogenesis. 14:1993;483-492.
11. Calaf G., Hang P.L., Alvarado M.V., Estrada S., Russo J. c-Ha-ras enhances the neoplastic transformation of human breast epithelial cells treated with chemical carcinogens. Int. J. Oncol. 6:1995;5-11.
12. 2-terminal kinase 1 by benzo(a)pyrene. Cancer Res. 58:1998;2102-2106.
13. Zhang P.L., Chai Y.L., Ho T.Y., Calaf G., Russo J. Allele loss and point mutation in codons 12 and 61 of the c-Ha-ras oncogene in carcinogen-transformed human breast epithelial cells. Mol. Carcinog. 9:1994;46-56.
14. Miranda E.I., Santana C., Rojas E., Hernández S., Ostrostry-Wegman P., García-Carrancá A. Induced mitotic death of HeLa cells by abnormal expression of c-Ha-ras. Mutat. Res. 349:1996;173-182.
15. Soule H.D., Maloney T.M., Wolman S.R., Peterson W.D. Jr., Brenz R., McGrath C.M., Russo J., Pauley R.J., Jones R.F., Brooks S.C. Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10. Cancer Res. 50:1990;6075-6086.
16. Sumner A.T. A simple technique for demonstrating heterochromatin. Exp. Cell Res. 75:1972;304-306.
17. Vidal B.C., Planding W., Mello M.L.S., Schenck U. Quantitative evaluation of Ag-NOR in liver by high-resolution image cytometry. Anal. Cell Pathol. 7:1994;27-41.
18. Vidal B.C., Barbisan L.F., Maria S.S., Russo J., Mello M.L.S. Apoptosis: identification by a critical electrolyte concentration method. Apoptosis. 1:1996;218-221.
19. Tolbert P.E., Shy C.M., Allen J.W. Micronuclei and other nuclear anomalies in buccal smears: methods development. Mutat. Res. 27:1992;69-77.
20. Fenech M. The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human populations. Mutat. Res. 285:1993;25-44.
21. Goodman L.A. Simultaneous confidence intervals for contrasts among multinomial populations. Ann. Math. Stat. 35:1964;716-725.
22. Denko N., Stringer J., Wani M., Stambrook P. Mitotic and post mitotic consequences of genomic instability induced by oncogenic Ha-ras. Somatic Cell Mol. Genet. 21:1995;241-253.
23. M.L.S. Mello, B.C. Vidal, J. Russo, Ha-ras oncogene effect on chromatin supraorganization of benzo[a]pyrene-transformed human breast epithelial cells. Anal. Cell. Pathol., 1999, in press.
24. Mello M.L.S., Lin T.Y., Russo J. Scanning microphotometry image analysis of Ha-ras-transformed human breast epithelial cells. Anal. Cell Pathol. 7:1994;301-319.
25. Falcieri E., Zamai L., Santi S., Cinti C., Gobbi P., Bosco D., Cataldi A., Betts C., Vitale M. The behaviour of nuclear domains in the course of apoptosis. Histochemistry. 102:1994;221-231.
26. Earnshaw W.C. Apoptosis: lessons from in vitro systems. Trends Cell Biol. 5:1995;217-220.