Heparin-bonded circuit with low systemic anticoagulation in a patient with heparin-induced thrombocytopenia: A case report

Journal of Extra-Corporeal Technology

Volumn 31, Issue 3, 1999, Pages 142-144

  O'Gara, Paul J ^a   Aldea, Gabriel S ^a   Shemin, Richard J ^a   Shapira, Oz M ^a  

^a BOSTON MEDICAL CENTER   (United States)

Author keywords

Cardiopulmonary bypass; Heparin bonded circuits; HIT; Thrombin antithrombin complexes; Thrombocytopenia

Indexed keywords

GLYCERYL TRINITRATE; HEPARIN; THROMBIN ANTITHROMBIN COMPLEX;

AGED; ANTICOAGULANT THERAPY; ARTICLE; CARDIOMYOPATHY; CARDIOPULMONARY BYPASS; CASE REPORT; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DRUG INDUCED DISEASE; ERYTHROCYTE TRANSFUSION; EXTRACORPOREAL CIRCULATION; HEART INFARCTION; HEMATOCRIT; HEPARINIZATION; HUMAN; MALE; THROMBOCYTE COUNT; THROMBOCYTOPENIA;

EID: 0033392908     PISSN: 00221058     EISSN: 29698960     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Demasi R, Bode AP, Knupp C, Bogey W, Powell S. Heparin-induced thrombocytopenia. Am Surg. 1994;60:26-29.
2. Greinacher A, Amiral J, Dummel V, Vissac A, Kifel V, Mueller-Eckhardt C. Laboratory diagnosis of heparin-associated thrombocytopenia and comparison of platelet aggregation test, heparin-induced platelet activation test, and platelet factor 4/heparin enzyme-linked immunosorbent assay. Transfusion. 1994;34:381-85.
3. Bauer TL, Arepally G, Konkle BA, et al. Prevalence of heparin associated antibodies without thrombosis in patients undergoing cardiopulmonary bypass surgery. Circulation. 1997;95:3242-46.
4. Schmitt BP, Adelman B. Heparin associated thrombocytopenia: A critical review and pooled analysis. Am J Med Sci. 1993;305:208-15.
5. Walls JT, Curtis JJ, Silver D, Boley TM, Schmaltz RA, Nawararawong W. Heparin-induced thrombocytopenia in open heart surgical patients: Sequelae of later recognition. Ann Thorac Surg. 1992;53:787-91.
6. O-Yurvati AH, Laub GW, Southgate TJ, Mcgrath LB. Heparinless cardiopulmonary bypass with Ancrod. Ann Thorac Surg. 1994;57:1656-8.
7. Chamberlin JR, Lewis B, Leya F, et al. Successful treatment of heparin-associated thrombocytopenia and thrombosis using Hirulog. Can J Cardiol. 1995;11:511-14.
8. Wilhelm MJ, Schmid C, Kececioglu D, Mollhoff T, Ostermann H, Scheld HH. Cardiopulmonary bypass in patients with heparin induced thrombocytopenia using Org 10172. Ann Thorac Surg. 1996;61:920-4.
9. Ganjoo AK, Harloff MG, Johnson WD. Cardiopulmonary bypass for heparin induced thrombocytopenia: Management with a heparin bonded circuit and Enoxparin. J Thorac Cardiovasc Surg. 1996;112:1390-2.
10. Aldea GS, Doursounian M, O'Gara P, et al. Heparin bonded circuits with a reduced anticoagulation protocol in primary CABG: A prospective randomized study. Ann Thorac Surg. 1996;62:410-8.
11. Shapira OM, Aldea GS, Zelinger J, et al. Enhanced blood conservation and improved clinical outcome after valve surgery using heparin-bonded cardiopulmonary bypass circuits. J Card Surg. 1996;11:307-17.
12. Aldea GS, O'Gara P, Shapira OM, et al. Effect of anticoagulation protocol on outcome in patients undergoing CABG with heparin-bonded cardiopulmonary bypass circuits. Ann Thorac Surg. 1998;65:425-33.