Successful treatment of Epstein-Barr virus-induced transverse myelitis with ganciclovir and cytomegalovirus hyperimmune globulin following unrelated bone marrow transplantation

Bone Marrow Transplantation

Volumn 24, Issue 12, 1999, Pages 1355-1358

  Gruhn, B ^a   Meerbach, A ^a   Egerer, R ^a   Mentzel, H J ^a   Hafer R ^a   Ringelmann, F ^a   Sauer, M ^a   Hermann, J ^a   Zintl, F ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Bone marrow transplantation; Epstein Barr virus; Transverse myelitis

Indexed keywords

AZATHIOPRINE; BUSULFAN; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; DEXAMETHASONE; GANCICLOVIR; HYPERIMMUNE GLOBULIN; IMMUNOGLOBULIN G; METHOTREXATE; METHYLPREDNISOLONE; PREDNISOLONE; TACROLIMUS; THYMOCYTE ANTIBODY;

ACUTE GRANULOCYTIC LEUKEMIA; ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; CEREBROSPINAL FLUID; DRUG EFFICACY; EPSTEIN BARR VIRUS; GRAFT VERSUS HOST REACTION; HUMAN; MALE; MYELITIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PERIPHERAL LYMPHOCYTE; PHYSICAL EXAMINATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SERODIAGNOSIS;

EID: 0033392316     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1702057     Document Type: Article

References (11)

1. Caldas C, Ambinder R. Epstein-Barr virus and bone marrow transplantation. Curr Opin Oncol 1995; 7: 102-106.
2. Grose C, Feorino PM. Epstein-Barr virus and transverse myelitis. Lancet 1973; 1: 892.
3. Berman M, Feldman S, Alter M et al. Acute transverse myelitis: incidence and etiologic considerations. Neurology 1981; 31: 966-971.
4. Caldas C, Bernicker E, Nogare AD, Luby JP. Case report: transverse myelitis associated with Epstein-Barr virus infection. Am J Med Sci 1994; 307: 45-48.
5. O'Reilly RJ, Small TN, Papadopoulos E et al. Biology and adoptive cell therapy of Epstein-Barr virus-associated lymphoproliferative disorders in recipients of marrow allografts. Immunol Rev 1997; 157: 195-216.
6. Lin JC, Smith MC, Pagano JS. Prolonged inhibitory effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine against replication of Epstein-Barr virus. J Virol 1984; 50: 50-55.
7. Ishida Y, Yokota Y, Tauchi H et al. Ganciclovir for chronic active Epstein-Barr virus infection. Lancet 1993; 341: 560-561.
8. Pirsch JD, Stratta RJ, Sollinger HW et al. Treatment of severe Epstein-Barr virus-induced lymphoproliferative syndrome with ganciclovir: two cases after solid organ transplantation. Am J Med 1989; 86: 241-244.
9. Oettle H, Wilborn F, Schmidt CA, Siegert W. Treatment with ganciclovir and Ig for acute Epstein-Barr virus infection after allogeneic bone marrow transplantation. Blood 1993; 82: 2257-2258.
10. Dellemijn PLI, Brandenburg A, Niesters HGM et al. Successful treatment with ganciclovir of presumed Epstein-Barr meningo-encephalitis following bone marrow transplant. Bone Marrow Transplant 1995; 16: 311-312.
11. Delone P, Corkill J, Jordan M et al. Successful treatment of Epstein-Barr virus infection with ganciclovir and cytomegalovirus hyperimmune globulin following kidney transplantation. Transplant Proc 1995; 27 (Suppl. 1): 58-59.