Oxygen consumption of cerebral cortex fails to increase during continued vibrotactile stimulation

Journal of Cerebral Blood Flow and Metabolism

Volumn 19, Issue 3, 1999, Pages 266-271

  Fujita, Hitoshi ^a,c   Kuwabara, Hiroto ^a,d   Reutens, David C ^a   Gjedde, Albert ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c Ehime Pref Iyomishima Hospital   (Japan)

^d WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cerebral blood flow; Cerebral oxidative metabolism; Physiologic activation; Positron emission tomography; Vibrotactile stimulation

Indexed keywords

OXYGEN;

AEROBIC METABOLISM; ARTICLE; BRAIN BLOOD FLOW; BRAIN CORTEX; BRAIN OXYGEN CONSUMPTION; CLINICAL ARTICLE; HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATIVE PHOSPHORYLATION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; TACTILE STIMULATION;

EID: 0033392096     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199903000-00004     Document Type: Article

References (17)

1. Ackermann RF, Lear JL (1989) Glycolysis-induced discordance between glucose metablic rates measured with radiolabelled fluorodeoxyglucose and glucose. J Cereb Blood Flow Metab 9:774-785
2. Applegate C, Fox FT, Raichle ME (1988) Habituation of cerebral blood flow response to cutaneous vibration. Neurology 38:s363
3. Baron JC, Rougemont D, Soussaline F, Bustany P, Crouzel C, Bousser MG, et al. (1984) Local interrelationships of cerebral oxygen consumption and glucose utilization in normal subjects and in ishemic stroke patients: a positron tomography study. J Cereb Blood Flow Metab 4:140-149
4. Cooke BE, Evans AC, Fanthome EA, Alarie R, Sendyk A (1988) Performance figures and images from the Therascan 3128 positron emission tomograph. IEEE Trans Nucl Sci NS 32:640-644
5. Evans AC, Beil C, Marrett S, Thompson CJ, Hakim A (1988) Anatomical-functional correlation using an adjustable MRI-based region of interest atlas with positron emission tomography. J Cereb Blood Flow Metab 8:513-530
6. Evans AC, Thompson CJ, Marrett S, Meyer E, Mazza M (1991) Performance evaluation of the PC-2048: a new 15-slice encoded-crystal PET scanner for neurological studies. IEEE Trans Med Imaging 10:89-98
7. Evans AC, Marrett S, Neelin P, Collins L, Worsley K, Dai W, et al. (1992) Anatomical mapping of functional activation in stereotactic coordinate space. Neuroimage 1:43-53
8. Fox PT, Raichle ME (1986) Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects. Proc Natl Acad Sci USA 83:1140-1144
9. Fox PT, Raichle ME, Mintun MA, Dence C (1988a) Nonoxidative glucose consumption during focal physiologic neural activity. Science 241:462-464
10. Fox PT, Mintun MA, Reiman EM, Raichle ME (1988b) Enhanced detection of focal brain responses using intersubject averaging and change-distribution analysis of subtracted PET images. J Cereb Blood Flow Melab 8:642-653
11. 1-map) and without ("CBF"-map) inclusion of a vascular compartment. Ann Nucl Med 7:s96-s97
12. 15O]water clearance in humans determined by PET. II. Vascular responses to vibrotactile stimulation. J Cereb Blood Flow Metab 17:73-79
13. 15O-water and positron emission tomoraphy. J Cereb Blood Flow Metab 7:13-20
14. Ginsberg MD, Chang JY, Kelley RE, Yoshii F, Barker WW, Ingenito G, et al. (1988) Increases in both cerebral glucose utilization and blood flow during execution of a somatosensory task. Ann Neurol 23:152-160
15. Gjedde A (1993) The energy cost of neuronal depolarization. In: Functional Organization of the Human Visual Cortex (Gulyas B, Ottoson D, Roland PE, eds), New York, Pergamon, pp 291-306
16. Gjedde A (1997) The relation between brain function and cerebral blood flow and metabolism. In: Cerebrovascular Disease (Hunt Batjer H, ed), Philadelphia, Lippincott-Raven, pp 23-40
17. 2O autoradiography and positron emission tomography, with respect to dispersion of the input function. J Cereb Blood Flow Metab 6:536-545