Synthesis and biological activity of 22-iodo- and (E)-20(22)-dehydro analogues of 1α,25-dihydroxyvitamin D3

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 12, 1999, Pages 2877-2889

  Sicinski, Rafal R ^a   Deluca, Hector F ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Antiproliferative agents; Molecular modeling mechanics; Receptor binding; Vitamin D3 analogues

Indexed keywords

20(22) DEHYDROCALCITRIOL; 22 IODOCALCITRIOL; CALCITRIOL; CALCITRIOL DERIVATIVE; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE; CALCIUM BLOOD LEVEL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CELL STRAIN HL 60; CHEMICAL REACTION; CONTROLLED STUDY; CYCLIZATION; DRUG ACTIVITY; DRUG CONFORMATION; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTESTINE; IODINATION; MALE; MODEL; MOLECULAR MODEL; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STRUCTURE ACTIVITY RELATION; SWINE;

ANIMALS; CALCITRIOL; CELL DIFFERENTIATION; HL-60 CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; RECEPTORS, CALCITRIOL; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

SUIDAE;

EID: 0033391499     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00249-7     Document Type: Article

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