Intravenous infusion of magnesium sulfate and regional redistribution of fetal blood flow during maternal hemorrhage in late-gestation gravid ewes

American Journal of Obstetrics and Gynecology

Volumn 181, Issue 6, 1999, Pages 1486-1494

  Moon, Paula F ^a   Ramsay, Margaret M ^a   Nathanielsz, Peter W ^a  

^a NONE

Author keywords

Fetal lamb; Hemorrhage; Hypovolemia; Magnesium sulfate; Regional blood flow

Indexed keywords

MAGNESIUM SULFATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; BRAIN BLOOD FLOW; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; FETUS CIRCULATION; GESTATIONAL AGE; HYPOVOLEMIA; NONHUMAN; PREECLAMPSIA; PREGNANCY COMPLICATION; PREMATURE LABOR; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; SEIZURE; SHEEP;

EID: 0033390935     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9378(99)70408-4     Document Type: Article

References (23)

1. 1. Belfort MA, Moise KJ. Effect of magnesium sulfate on maternal brain blood flow in preeclampsia: a randomized, placebo-controlled study. Am J Obstet Gynecol 1992;167:661-6.
2. 2. James MF. Clinical use of magnesium infusions in anesthesia. Anesth Analg 1992;74:129-36.
3. 3. Lucas MJ, Leveno KJ, Cunningham FG. A comparison of magnesium sulfate with phenytoin for the prevention of eclampsia. N Engl J Med 1995;333;201-5.
4. 4. Higby K, Xenakis EM, Pauerstein CJ. Do tocolytic agents stop preterm labor? A critical and comprehensive review of efficacy and safety. Am J Obstet Gynecol 1993;168:1247-59.
5. 5. Besinger RE, Moniak CW, Paskiewicz LS, Fisher SG, Tomich PG. The effect of tocolytic use in the management of symptomatic placenta previa. Am J Obstet Gynecol 1995;172:1770-8.
6. 7. FineSmith RB, Roche K, Yellin PB, Walsh KK, Shen C, Zeglis M, et al. Effect of magnesium sulfate on the development of cystic periventricular leukomalacia in preterm infants. Am J Perinatol 1997;14:303-7.
7. 8. Rouse DJ, Hauth JC, Nelson KG, Goldenberg RL. The feasibility of a randomized clinical perinatal trial: maternal magnesium sulfate for the prevention of cerebral palsy. Am J Obstet Gynecol 1996;175:701-5.
8. 9. Schendel DE, Berg CJ, Yeargin-Allsopp M, Boyle CA, Decoufle P. Prenatal magnesium sulfate exposure and the risk for cerebral palsy or mental retardation among very low-birth-weight children aged 3 to 5 years. JAMA 1996;276:1805-10.
9. 10. Nelson KB, Grether JK. Can magnesium sulfate reduce the risk of cerebral palsy in very low birthweight infants? Pediatrics 1995;95:263-9.
10. 11. Blair E, Palmer L, Stanley F. Cerebral palsy in very low birth weight infants, pre-eclampsia and magnesium sulphate [letter]. Pediatrics 1996;98:780-1.
11. 12. Reynolds JD, Chestnut DH, Dexter F, McGrath J, Penning DH. Magnesium sulfate adversely affects fetal lamb survival and blocks fetal cerebral blood flow response during maternal hemorrhage. Anesth Analg 1996;83:493-9.
12. 13. Altura BM, Altura BT. Magnesium and vascular tone and reactivity. Blood Vessels 1978;15:5-16.
13. 14. Mason BA, Standley CA, Whitty JE, Cotton DB. Fetal ionized magnesium levels parallel maternal levels during magnesium sulfate therapy for preeclampsia. Am J Obstet Gynecol 1996;175:213-7.
14. 15. Hallack M, Berry SM, Madincea F, Romero R, Evans MI, Cotton DB. Fetal serum and amniotic fluid magnesium concentrations with maternal treatment. Obstet Gynecol 1993;81:185-8.
15. 16. Buchwalder LF, Lin M, McDonald TJ, Nathanielsz PW. Fetal sheep adrenal blood flow responses to hypoxemia after splanchnicotomy using fluorescent microspheres. J Appl Physiol 1998;84:82-9.
16. 17. Buckberg GD, Luck JC, Payne DB, Hoffman JI, Archie JP, Fixler DE. Some sources of error in measuring regional blood flow with radioactive microspheres. J Appl Physiol 1971;31:598-604.
17. 18. de Haan HH, Gunn AJ, Williams CE, Heymann MA, Gluckman PD. Magnesium sulfate therapy during asphyxia in near-term fetal lambs does not compromise the fetus but does not reduce cerebral injury. Am J Obstet Gynecol 1997;176:18-27.
18. 19. Barri M, Abbas SK, Pickard DW, Hammonds RG, Wood WI, Caple IW, et al. Fetal magnesium homeostasis in the sheep. Exp Physiol 1990;75:681-8.
19. 20. Rudolph AM. The fetal circulation and its response to stress. J Dev Physiol 1984;6:11-19.
20. 21. Giussani DA, Spencer JA, Hanson M. Fetal cardiovascular reflex responses to hypoxaemia. Fetal Maternal Med Rev 1994;6:17-37.
21. 22. Lothman EW, Hatfield JM, Zorumski CF, Contry JA, Moon PF, Perlin JB. Kindling with rapidly recurring hippocampal seizures. Brain Res 1985;360:83-91.
22. 23. Tsuda T, Kogure K, Nishioka K, Watanabe T. Mg2+ administration up to twenty-four hours following preperfusion prevents ischemic damage of the Cal neurons in the rat hippocampus. Neuroscience 1991;44:335-41.
23. 24. McDonald JW, Silverstein FS, Johnston MV. Magnesium reduces N-methyl-D-aspartate (NMDA)-mediated brain injury in perinatal rats. Neurosci Lett 1990;109:234-8.