Cognitive dysfunction in schizophrenia and its importance to outcome: The place of atypical antipsychotics in treatment

Journal of Clinical Psychiatry

Volumn 60, Issue SUPPL. 23, 1999, Pages 25-26

  Velligan, Dawn I ^a   Miller, Alexander L ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; HALOPERIDOL; NEUROLEPTIC AGENT; QUETIAPINE;

ADULT; ARTICLE; CASE REPORT; COGNITIVE DEFECT; COPING BEHAVIOR; EXTRAPYRAMIDAL SYMPTOM; HUMAN; MALE; MEMORY; NEGATIVE SYNDROME; PRIORITY JOURNAL; REMISSION; SCHIZOPHRENIA; SOCIAL BEHAVIOR;

ADULT; ANTIPSYCHOTIC AGENTS; COGNITION DISORDERS; DIBENZOTHIAZEPINES; HALOPERIDOL; HUMANS; MALE; MODELS, PSYCHOLOGICAL; NEUROPSYCHOLOGICAL TESTS; PSYCHOMETRICS; REPRODUCIBILITY OF RESULTS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; TREATMENT OUTCOME;

EID: 0033390894     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Gold JM, Harvey PD. Cognitive deficits in schizophrenia. Psychiatr Clin North Am 1993;16:295-312
2. Nuechterlein KH. Dawson ME. Information processing and attentional functioning in the developmental course of schizophrenic disorders. Schizophr Bull 1984;10:160-203
3. Saykin AJ, Gur RC, Gur RE, et al. Neuropsychological function in schizophrenia: selective impairment in memory and learning. Arch Gen Psychiatry 1991;48:618-624
4. Jager J, Douglas E. Neuropsychiatric rehabilitation for persistent mental illness. Psychiatr Q 1992;63:71-94
5. Morice R, Delahunty A. Frontal/executive impairments in schizophrenia. Schizophr Bull 1996;22:125-137
6. Velligan DI, Bow-Thomas CC. Executive function in schizophrenia. Sem Clin Neuropsychiatry 1999;4:24-33
7. Green MF. What are the functional consequences of neurocognitive deficits in schizophrenia? Am J Psychiatry 1996;153:321-330
8. Velligan DI, Mahurin RK, Diamond PL. The functional significance of symptomatology and cognitive function in schizophrenia. Schizophr Res 1997;25:21-31
9. Harvey PD, Howanitz E, Parrella M, et al. Symptoms, cognitive functioning, and adaptive skills in geriatric patients with lifelong schizophrenia: a comparison across treatment sites. Am J Psychiatry 1998;155:1080-1086
10. Sharma T, Mockler D. The cognitive efficacy of atypical antipsychotics in schizophrenia. J Clin Psychopharmacol 1998;18:12S-19S
11. Cassens G, Inglis AK, Appelbaum PS, et al. Effects on neuropsychological function in chronic schizophrenic patients. Schizophr Bull 1990;16: 477-499
12. Mortimer AM. Cognitive function in schizophrenia: do neuroleptics make a difference? Pharmacol Biochem Behav 1996;56:789-795
13. Thomas CS, Lewis S. Which atypical antipsychotic? Br J Psychiatry 1997; 172:106-109
14. Marder SR, Meibach RC. Risperidone in the treatment of schizophrenia. Am J Psychiatry 1994;151:825-835
15. Hellewell JSE. A review of tolerability of Seroquel (quetiapine) in the treatment of schizophrenia. In: Advances in Preclinical and Clinical Psychiatry. Excerpta Medica. In press
16. Hoff AL, Riordan H, O'Donnell DW, et al. Neuropsychological functioning of first-episode schizophreniform patients. Am J Psychiatry 1992;149: 898-902
17. Meltzer H. Dimensions of outcome with clozapine. Br J Psychiatry 1992; 160(suppl 17):46-53
18. Goldberg TE, Weinberger DR. The effects of clozapine on neurocognition: an overview. J Clin Psychiatry 1994;55:88-90
19. Green MF, Marshall BD Jr, Wirshing WC. Does risperidone improve verbal working memory in treatment-resistant schizophrenia? Am J Psychiatry 1997;154:799-804
20. Velligan DI, Newcomer JW, Pultz J. et al. Changes in cognitive functioning with quetiapine fumarate versus haloperidol. In: New Research Program and Abstracts of the 152nd Annual Meeting of the American Psychiatric Association; May 20, 1999; Washington, DC. Abstract NR633:247
21. Arvanitis LA, Rak IW. Efficacy, safety and tolerability of Seroquel (quetiapine) in elderly subjects with psychotic disorders. Presented at the 151st Annual Meeting of the American Psychiatric Association; May 30-June 5, 1998; Toronto, Ontario, Canada
22. Stip E, Lussier I, Babai M, et al. Seroquel and cognitive improvement in patients with schizophrenia. Biol Psychiatry 1996;40:434-435