Spontaneously occurring anti-PTH autoantibodies must be considered in the differential diagnosis of patients with elevated serum PTH levels

Journal of Endocrinological Investigation

Volumn 22, Issue 11, 1999, Pages 829-834

  Cavaco, B ^a   Leite, Valeriano ^a   Loureiro, M M ^a   Ferreira, M F ^a   Pereira, M C ^a   Santos, M A ^a   Sobrinho, L G ^a  

^a INSTITUTO PORTUGUÊS DE ONCOLOGIA DE LISBOA FRANCISCO GENTIL   (Portugal)

Author keywords

Autoantibodies; Chromatography; Hypocalcemia; Immunoassay; Parathyroid hormone; Prolactin

Indexed keywords

25 HYDROXYVITAMIN D; AUTOANTIBODY; CALCITRIOL; CALCIUM; CYCLOPHOSPHAMIDE; DEXAMETHASONE; FLUOROURACIL; HORMONE ANTIBODY; IMMUNOGLOBULIN G; IODINE 131; LEVOTHYROXINE; MAGNESIUM; METHOTREXATE; PARATHYROID HORMONE; PROLACTIN; VITAMIN D;

ADULT; ARTICLE; CALCIUM BLOOD LEVEL; CASE REPORT; DIFFERENTIAL DIAGNOSIS; FEMALE; HUMAN; HYPERPROLACTINEMIA; HYPOCALCEMIA; INTRADUCTAL CARCINOMA; IRRITABILITY; LUNG METASTASIS; MASTECTOMY; MUSCLE CRAMP; PAGET NIPPLE DISEASE; PARATHYROID HORMONE BLOOD LEVEL; PARESTHESIA; THYROID PAPILLARY CARCINOMA; THYROIDECTOMY; VERTIGO;

EID: 0033389768     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03343654     Document Type: Article

References (16)

1. Uchigata Y., Kuwata S., Tokunaga K., Eguchi Y., Takayama-Hasumi S., Miyamoto M., Omori Y., Juji T., Hirata Y. Strong association of insulin autoimmune syndrome with HLA-DR4. Lancet 1992, 339: 393-394.
2. Baba S., Morita S., Mizuno N., Okada K. Autoimmunity to glucagon in a diabetic not on insulin. Lancet 1976, 2: 585.
3. Beck-Peccoz P., Romelli P.B., Cattaneo M.G., Faglia G., White E.L., Barlow J.W., Stockigt J.R. Evaluation of free thyroxine methods in the presence of iodothyronine-binding autoantibodies. J. Clin. Endocrinol. Metab. 1984, 58: 736-739.
4. Leite V., Cosby H., Sobrinho L.G., Fresnoza A., Santos M.A., Friesen H.G. Characterization of big, big prolactin in patients with hyperprolactinemia. Clin. Endocrinol. (Oxf.) 1992, 37: 365-372.
5. Cavaco B., Leite V., Santos M.A., Arranhado E., Sobrinho L.G. Some forms of big, big prolactin behave as a complex of monomeric prolactin with an immunoglobulin G in patients with macroprolactinemia or prolactinoma. J. Clin. Endocrinol. Metab. 1995, 80: 2342-2346.
6. Jüppner H., Atkinson M.J., Baethke R., Hesch R.D. Autoantibodies against parathyroid hormone in a patient with terminal renal insufficiency. Lancet 1984, 1: 1379-1381.
7. Wilkinson M., McElduff A., Wilson J. Spontaneously occurring antibodies to parathyroid hormone. J. Clin. Endocrinol. Metab. 1990, 70: 1744-1749.
8. Kasono K., Sato K., Suzuki T., Ohmura E., Demura R., Shizume K., Tsushima T., Demura H. Falsely elevated serum parathyroid hormone levels due to immunoglobulin G in a patient with idiophatic hypoparathyroidism. J. Clin. Endocrinol. Metab. 1991, 72: 217-222.
9. McElduff A., Lackmann M., Wilkinson M. Antiidiotypic PTH antibodies as a cause of elevated immunoreactive parathyroid hormone in idiopathic hypoparathyroidism, a second case: another manifestation of autoimmune endocrine disease? Calcif Tissue Int. 1992, 51: 121-126.
10. Melick R.A., Gill L.R. Jr., Berson S.A., Yalow R.S., Bartter F.C., Potts LT. Jr., Aurbach G.D. Antibodies and clinical resistance to parathyroid hormone. N. Engl. J. Med. 1967, 276: 144-147.
11. Audran M., Basle M.-F., Defontaine A., Jallet P., Bidet M.T., Ermias A., Tanguy G., Pouplard A., Reeve L., Zanelli J., Renier J.C. Transient hypoparathyroidism induced by synthetic human parathyroid hormone (1-34) treatment. J. Clin. Endocrinol. Metab. 1987, 64: 937-943.
12. Roth J., Glick S.M., Yalow R.S., Berson S.A. Antibodies to human growth hormone (HGH) in human subjects treated with HGH. J. Clin. Invest. 1964, 43: 1056-1065.
13. Frasier S.D., Smith F.G. Jr. Antibodies to human growth hormone. Development during therapy with human growth hormone. Am. J. Dis. Child. 1966, 712: 383-388.
14. Spitz I., Bell J., Arad G., Benveniste R., Rabinowitz D. Development of anti-human FSH antibody in a patient with isolated FSH deficiency. J. Clin. Endocrinol. Metab. 1973, 36: 684-690.
15. Healy D.L, Fraser I.S., Lee V.W., Shearman R.P., Burger H.G. Characteristics of an antiluteinizing hormone isoantibody produced during gonadotropin induction of ovulation. J. Clin. Endocrinol. Metab. 1978, 47: 823-828.
16. 131I insulin metabolism in human subjects: demonstration of insulin binding globulin in the circulation of insulin-treated subjects. J. Clin. Invest. 1956, 35: 170-190.