Analysis of the 5'-upstream regions of the human relaxin H1 and H2 genes and their chromosomal localization on chromosome 9p24·1 by radiation hybrid and breakpoint mapping

Journal of Molecular Endocrinology

Volumn 23, Issue 3, 1999, Pages 355-365

  Garibay Tupas, J L ^a,c   Csiszar K ^a   Fox, M ^b   Povey, S ^b   Bryant Greenwood, G D ^a  

^a UNIVERSITY OF HAWAII   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c Dept of Anat and Repro Biology ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RELAXIN;

ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 9P; CHROMOSOME MAP; GENE STRUCTURE; GENETIC TRANSCRIPTION; HUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION;

EID: 0033385993     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0230355     Document Type: Article

References (36)

1. Bogic LV, Yamamoto SY, Millar LK & Bryant-Greenwood GD 1997 Developmental regulation ot the human relaxin genes in the decidua and placenta: overexpression in the preterm premature rupture of the fetal membranes. Biology of Reproduction 57 908-920.
2. Bohm SK, Gum JR Jr, Erickson RH, Hicks JW & Kim YS 1995 Human dipeptidyl peptidase IV gene promoter: tissue specific regulation from a TATA-less GC-rich sequence characteristic of a housekeeping gene promoter. Biochemistry Journal 311 835-843.
3. Bouzyk M, Bryant SP, Evans C, Guioli S, Ford S, Schmidt K, Goodfellow PN, Povey S, Rebello M, Rousseax S & Spurr NK 1997 Integrated radiation hybrid and yeast artificial chromosome map of chromosome 9. European Journal of Human Genetics 5 299-307.
4. Bryant-Greenwood GD & Schwabe C 1994 Human relaxins: chemistry and biology. Endocrine Review 15 5-26.
5. Bryant-Greenwood GD, Rutanen EM, Partanen S, Coelho TK & Yamamoto SY 1993 Sequential appearance of relaxin, prolactm and IGFBP-1 during growth and differentiation of the human endometnum. Molecular and Cellular Endocnnology 95 23-29.
6. Carr-Hill RA & Hall M 1985 The repetition of spontaneous preterm labour. British Journal of Obstetrics and Gynaecology 92 921-928.
7. Chassin D, Laurent A, Janneau J-L, Berger R & Belief D 1995 Cloning of a new member of the insulin gene superfamily (INSL4) expressed in human placenta. Genumics 29 465-470.
8. Crawford RJ, Hudson P, Shine J, Niall HD, Eddy RL & Shows TB 1984 The two human relaxin genes are on chromosome 9. EMBO Journal 3 2341-2345.
9. Evans BA, Fu P & Tregear GW 1994 Characterization of primate relaxin genes. Endocrine Journal 2 81-86.
10. 32P-labelled human relaxins to the human fetal membranes. Journal of Endocrinology 145 441-448.
11. Garibay-Tupas JL, Bao S, Kim MT, Tashima LS & Bryant-Greenwood GD 2000 Isolation and analysis of the 3′-untranslated regions of the human relaxin H1 and H2 genes. Journal of Molecular Endocrinology (In Press).
12. Gillett GT, McConville CM, Byrd PJ, Stankovic T, Taylor AM, Hunt DM, West LK, Fox MF, Povey S & Benham FJ 1993 Irradiation hybrids for human chromosome 11: characterization and use for generating region-specific markers in 11q14-q23. Genomics 15 332-341.
13. Gunnersen JM, Roche PJ, Tregear GW & Crawford RJ 1995 Characterization of human relaxin gene regulation in the relaxin-expressing human prostate adenocarcinoma cell line LNCaP.FGC. Journal of Molecular Endocrinology 15 153-166.
14. Gyapay G, Schmitt K, Fizames C, Jones H, Vega-Czarny N, Spillett D, Muselet D, Prud-Homme JF, Dib C, Auffray C, Morisette J, Weissenbach J & Goodfellow PN 1996 A radiation hybrid map of the human genome. Human Molecular Genetics 5 339-346.
15. Hansell DJ, Bryant-Greenwood GD & Greenwood FC 1991 Expression of the human relaxin H1 gene in the decidua, trophoblast, and prostate. Journal of Clinical Endocrinology and Metabolism 72 899-904.
16. Harper ME, Ullrich A & Saunders GF 1981 Localization of the human insulin gene to the distal end of the short arm of chromosome 11. Proceedings of the National Academy of Sciences of the USA 78 4458-4460.
17. Haley J, Crawford R, Hudson P, Scanlon D, Tregear G, Shine J & Niall HJ 1987 Porcine relaxin. Gene structure and expression. Journal of Biological Chemistry 262 11940-11946.
18. Hudson P, Haley J, Cronk M, Shine J & Niall H 1983 Structure of a genomic clone encoding biologically active human relaxin. Nature 291 127-131.
19. Hudson P, John M, Crawford R, Haralamhidis J, Scanlon D, Gorman J, Tregear G, Shine J & Niall H 1984 Relaxin gene expression in human ovaries and the predicted structure of a preprorelaxin by analysis of cDNA clones. EMBO Journal 3 2333-2339.
20. MacLaren DC & Clarke S 1996 Rapid mapping of genomic P1 clones: the mouse L-isoaspartyl/D-aspartyl methyltransferase gene. Genomics 35 299-307.
21. McRory JE & Sherwood NM 1997 Ancient divergence of insulin and insulin-like growth factor. DNA and Cell Biology 16 939-949.
22. Meloni R, Albanese V, Ravassard P, Treilhou F & Mallet J 1998 A tetranucleotide polymorphic microsatellite, located in the first intron of the tyrosine hydroxylase gene, acts as a transcription regulatory element in vitro. Human Molecular Genetics 3 423-428.
23. Migone A, Emanuel I, Mueller B, Daling J & Little RE 1991 Gestational duration and birthweight in white, black, and mixed-race babies. Paediatrics Perinatology and Epidemiology 5 378-391.
24. Porter TF, Fraser AM, Hunter CY, Ward R & Varner MW 1997 The risk of preterm birth across generations. Obstetrics and Gynecology 90 63-67.
25. Qin X, Garibay-Tupas J, Chua PK, Cachola L & Bryant-Greenwood GD 1997a An autocrine/paracrine role of human decidual relaxin. I. Interstitial collagenase (MMP-1) and tissue plasmtnogen activator. Biology of Reproduction 56 800-811.
26. Qin X, Chua PK, Ohira RH & Bryarit-Greenwood GD 1997b An autocrine/paracrine role of human decidual relaxin. II. Stromelysin (MMP-3) and tissue inhibitor of matrix metalloproteinase-1(TIMP-1). Biology of Reproduction 56 812-820.
27. Roberts AK, Monzon-Eordonaba F, Van Deerlin PG, Holder J, Macones GA, Morgan MA, Strauss JF & Parry S 1999 Association of polymorphism within the promoter ot the tumor necrosis factor α gene with increased risk of preterm premature rupture of the fetal membranes. American Journal of Obstetrics and Gynecology 180 1297-1302.
28. Sakhun V, Ali SM, Greenwood FC & Bryant-Greenwood GD 1990 Human relaxin in the amnion, chorion, decidua parietalis, basal plate and placental trophoblast by immunocytochemistry and Northern analysis. Journal of Clinical Endocrinology and Metabolism 70 508-514.
29. Sanger F, Nicklen S & Coulson AR 1977 DNA sequencing with chain-terminating inhibitors. Proceeding of the National Academy of Science of the USA 74 5463-5467.
30. Shiono PH & Klebanoff MA 1986 Ethnic differences in preterm and very preterm delivery. Amarican Journal of Public Health 76 1317-1321.
31. Stein L. Kruglyak L, Slonim D & Lander E 1995 'RHMAPPER', unpublished software, Whitehead Institute/MIT Center for Genome Research. Available at http://www.genome.wi.mit.edu/ftp/puh/sottware/rhmapper and via anonymous ftp to ftp.genome.wi.mit.edu, directory/pub/software/rhmapper
32. Sternberg N, Smoller D & Braden T 1994 Three new developments in P1 cloning. Increased cloning efficiency, improved clone recovery, and a new P1 mouse library. Genetics Analysis, Techniques and Applications 11 171-180.
33. Szabo Z, Light E, Boyd CD & Csiszar K 1997 The human lysyl oxidase-like gene maps between STS markers D15S215 and GHLC.GCT7C09 on chromosome 15. Human Genetics 101 198-200.
34. Tashima LS, Mazoujian G & Bryant-Greenwood GD 1994 Human relaxins in normal benign and neoplastic breast tissue. Journal of Molecular Endocrinology 12 351-364.
35. Walter M, Spillett D, Thomas P, Weissenbach J & Goodfellow P 1994 A method for constructing radiation hybrid maps of whole genomes. Nature Genetics 7 22-28.
36. Ye K, Dinarello CA & Clark BD 1993 Identification of the promoter region of human interleukin 1 type I receptor gene: multiple initiation sites, high G+C content, and constitutive expression. Proceeding of the National Academy of Sciences of the USA 90 2295-2299.