Use of sterol mutants as probes for sterol functions in the yeast, Saccharomyces cerevisiae

Critical Reviews in Biochemistry and Molecular Biology

Volumn 34, Issue 6, 1999, Pages 399-404

  Parks, Leo W ^a   Crowley, James H ^a   Leak, Frank W ^a   Smith, Steven J ^a   Tomeo, Michele E ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ERGOSTEROL; METHYLTRANSFERASE; OXIDOREDUCTASE; STEROL; ZYMOSTEROL;

FUNGUS GROWTH; GENE MUTATION; GENE SEQUENCE; MOLECULAR BIOLOGY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; REVIEW; SACCHAROMYCES CEREVISIAE; STEROL METABOLISM; STEROL SYNTHESIS; STRUCTURAL GENE; YEAST;

SACCHAROMYCES CEREVISIAE;

EID: 0033385497     PISSN: 10409238     EISSN: None     Source Type: Journal    
DOI: 10.1080/10409239991209381     Document Type: Review

References (45)

1. Gerard, E., Sur les cholesterines des cryptogames, J. Pharm. Chim., 1, 601, 1895.
2. Parks, L. W., Metabolism of sterols in yeast, Crit. Rev. Microbiol., 6, 301, 1978.
3. Adams, B. G. and Parks, L. W., Evidence for dual physiological forms of ergosterol in Saccharomyces cerevisiae, J. Cell. Physiol., 70, 161, 1967.
4. Adelberg, E. A., Roslanskyu, P. F., Myers, J. W., and Coughlin, C. A., Attempted induction of microbial mutants requiring steroidal growth factors, J. Bacteriol., 69, 733, 1955.
5. Woods, R. A., Hogg, J., and Miller, L., Changes in the sterol content of nystatin-resistant mutants of yeast, Heredity, 24, 516, 1969.
6. Parks, L. W. and Casey, W. M., Physiological implications of sterol biosynthesis in yeast, Annu. Rev. Microbiol., 49, 95, 1995.
7. McCammon, M. T., Hartmann, M. A., Bottema, C. D. K., and Parks, L. W., Sterol methylation in Saccharomyces cerevisiae, J. Bacteriol., 157, 475, 1984.
8. Gaber, R. F., Copple, D. M., Kennedy, B. K., Vidal, M., and Bard, M., The yeast gene ERG6 is required for normal membrane function but is not essential for biosynthesis of the cell-cycle-sparking sterol, Mol. Cell. Biol., 9, 3447, 1989.
9. Arthington, B. A., Bennett, L. G., Skatrud, P. L., Guynn, C. J., Barbuch, R. J., Ulbright, C. E., and Bard, M., Cloning, disruption, and sequence of the gene encoding yeast C-5 sterol desaturase, Gene, 102, 39, 1991.
10. Lorenz, R. T. and Parks, L. W., Cloning, sequencing, and disruption of the gene encoding sterol C-14 reductase in Saccharomyces cerevisiae, DNA Cell Biol., 11, 685, 1992.
11. Marcireau, C., Guyonnet, D., and Karst, F., Construction and growth properties of a yeast strain defective in sterol 14-reductase, Curr. Genet., 22, 267, 1992.
12. Lai, M. H., Bard, M., Pierson, C. A., Alexander, J. F., Goebl, M., Carter, G. T., and Kirsch, D. R., The identification of a gene family in the Saccharomyces cerevisiae ergosterol biosynthetic pathway, Gene, 140, 41, 1994.
13. Hays, P. R., Parks, L. W., Pierce, H. D., Jr., and Oehlschlager, A. C., Accumulation of ergosta-8,14-dien-3ß-ol by Saccharomyces cerevisiae cultured with an azasterol antimycotic agent, Lipids, 12, 666, 1977.
14. Baloch, R. I., Mercer, E. I., Wiggins, T. E., and Baldwin, B. C., Inhibition of ergosterol biosynthesis in Saccharomyces cerevisiae and Ustilago maydis by tridemorph, fenpropimorph, and fenpropidin, Phytochemistry, 23, 2219, 1984.
15. 14-reductase by fenpropimorph, tridemorph, and fenpropidin in cell-free enzyme systems from Saccharomyces cerevisiae, Phytochemistry, 26, 663, 1987.
16. Ashman, W. H., Barbuch, R. J., Ulbright, C. E., Jarrett, H. J., and Bard, M., Cloning and disruption of the yeast C-8 sterol isomerase gene, Lipids, 26, 628, 1991.
17. 8-7-isomerase in the sensitivity of Saccharomyces cerevisiae to fenpropimorph, FEMS Microbiol. Lett., 122, 223, 1994.
18. Lorenz, R. T. and Parks, L. W., Physiological effects of fenpropimorph on wild-type Saccharomyces cerevisiae and fenpropimorph-resistant mutants, Antimicrob. Agents Chemother., 35, 1532, 1991.
19. Crowley, J. H., Lorenz, R. T., and Parks, L. W., Fenpropimorph affects uptake of uracil and cytosine in Saccharomyces cerevisiae, Antimicrob. Agents Chemother., 38, 1004, 1994.
20. Steel, C. C., Baloch, R. I., Mercer, E. I., and Baldwin, B. C., The intracellular location and physiological effects of abnormal sterols in fungi grown in the presence of morpholine and functionally related fungicides, Pestic. Biochem. Physiol., 33, 101, 1989.
21. Bard, M., Lees, N. D., Burrows, L. S., and Kleinhaus, F. W., Differences in crystal violet uptake and cation-induced death among yeast sterol mutants, J. Bacteriol., 135, 1146, 1978.
22. Welihinda, A. A., Beavis, A. D., and Trumbly, R. J., Mutations in LIS1 (ERG6) gene confer increased sodium and lithium uptake in Saccharomyces cerevisiae, Biochim. Biophys. Acta, 1193, 107, 1994.
23. Vogel, J. P., Lee, J. N., Kirsch, D. R., Rose, M. D., and Sztul, E. S., Brefeldin A causes a defect in secretion in Saccharomyces cerevisiae, J. Biol. Chem., 268, 3040, 1993.
24. Graham, T. R., Scott, P. A., and Emr, S. D., Brefeldin A reversibly blocks early but not late protein transport steps in the yeast secretory pathway, EMBO J., 12, 869, 1993.
25. Grenson, M., Hou, C., and Crabeel, M., Multiplicity of the amino acid permeases in Saccharomyces cerevisiae, J. Bacteriol., 103, 770, 1970.
26. Kotyk, A. and Dvorakova, M., Transport of L-tryptophan in Saccharomyces cerevisiae, Folia Microbiol., 35, 209, 1990.
27. Tomeo, M. E., Fenner, G., Tove, S. R., and Parks, L. W., Effect of sterol alterations on conjugation in Saccharomyces cerevisiae, Yeast, 8, 1015, 1992.
28. Leber, R., Zinser, E., Zellnig, G., Paultauf, F., and Daum, G., Characterization of lipid particles of the yeast, Saccharomyces cerevisiae, Yeast, 10, 1421, 1994.
29. Cleves, A. E. and Bankaitis, V. A., Secretory pathway function in Saccharomyces cerevisiae, Adv. Microb. Physiol., 33, 73, 1992.
30. Semenza, J. C., Hardwick, K. G., Dean, N., and Pelham, H. R. B., ERD2, a gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway, Cell, 61, 1349, 1990.
31. Hardwick, K. G. and Pelham, H. R. B., SED6 is identical to ERG6 and encodes a putative methyltransferase required for ergosterol biosynthesis, Yeast, 10, 265, 1994.
32. Lorenz, R. T., Casey, W. M., and Parks, L. W., Structural discrimination in the sparking function of sterols in the yeast Saccharomyces cerevisiae, J. Bacteriol., 171, 6169, 1989.
33. Rodriguez, R. J. and Parks, L. W., Structural and physiological features of sterols necessary to satisfy bulk membrane and sparking requirements in yeast sterol auxotrophs, Arch. Biochem. Biophys., 225, 861, 1983.
34. Rodriguez, R. J., Low, C., Bottema, C. D. K., and Parks, L. W., Multiple functions for sterols in Saccharomyces cerevisiae, Biochim. Biophys. Acta, 837, 336, 1985.
35. Thompson, E. D. and Parks, L. W., Effect of altered sterol composition on the growth characteristics of Saccharomyces cerevisiae, J. Bacteriol., 120, 779, 1974.
36. Taylor, F. R., Rodriguez, R. J., and Parks, L. W., A requirement for a second sterol biosynthetic mutation to allow for viability of a sterol C-14 demethylation defect in Saccharomyces cerevisiae, J. Bacteriol., 155, 64, 1983.
37. Smith, S. J. and Parks, L. W., The ERG3 gene in Saccharomyces cerevisiae is required for the utilization of respiratory substrates and in heme-deficient cells, Yeast, 9, 1177, 1993.
38. Parks, L. W., Smith, S. J., and Crowley, J. H., Biochemical and physiological effects of sterol alterations in yeast, Lipids, 30, 227, 1995.
39. Taguchi, N., Takano, Y., Julmanop, C., Wang, Y., Stock, S., Takemoto, J., and Miyakawa, T., Identification and analysis of the Saccharomyces cerevisiae SYR1 gene reveals that ergosterol is involved in the action of syringomycin, Microbiology, 140, 353, 1994.
40. Ingram, M., An Introduction to the Biology of Yeasts, Pitman Publishing, New York, 1955.
41. Lodder, J. and Kreger-Van Rij, N. J. W., The Yeasts, a Taxonomic Study, Interscience Publishers, New York, 1952.
42. Mrak, E. M. and McClung, L. S., Yeast occurring on grapes and grape products in California, J. Bacteriol., 40, 395, 1940.
43. Mrak, E. M. and Phaff, H. J., Yeast, Annu. Rev. Microbiol., 2, 1, 1948.
44. Lewis, T. A., Taylor, F. R., and Parks, L. W., Involvement of heme biosynthesis in control of sterol uptake by Saccharomyces cerevisiae, J. Bacteriol., 163, 199, 1985.
45. Shinabarger, D. L., Keesler, G. A., and Parks, L. W., Regulation by heme of sterol uptake in Saccharomyces cerevisiae, Steroids, 53, 607, 1989.