Expression of aspartoacylase activity in cultured rat macroglial cells is limited to oligodendrocytes

Journal of Molecular Neuroscience

Volumn 13, Issue 1-2, 1999, Pages 47-53

  Baslow, Morris H ^a   Suckow, Raymond F ^b   Sapirstein, Victor ^a   Hungund, B L ^b  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

Aspartoacylase; Astrocytes; Brain; Canavan disease; Molecular water pump; Oligodendrocytes

Indexed keywords

AMIDASE; ASPARTOACYLASE; HYDROLASE; N ACETYLASPARTIC ACID; N ACETYLHISTIDINE; UNCLASSIFIED DRUG; WATER;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN EDEMA; CANAVAN DISEASE; CONTROLLED STUDY; ENZYME ACTIVITY; GOLDFISH; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; MACROGLIA; NEWBORN; NONHUMAN; OLIGODENDROGLIA; PROTEIN EXPRESSION; RAT;

ANIMALIA; CARASSIUS AURATUS; VERTEBRATA;

EID: 0033384017     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1385/jmn:13:1-2:47     Document Type: Article

References (24)

1. Adachi M. and Volk B. W. (1968) Protracted form of spongy degeneration of the central nervous system (van Bogaert and Bertrand type) Neurology 18, 1084-1092.
2. Baslow M. H. (1967) Temperature adaptation and the central nervous system of fish, in Molecular Mechanisms of Temperature Adaptation (Prosser C. L., ed), AAAS Symposium Volume, Publication 84, Washington, DC, pp. 205-226.
3. Baslow M. H. (1997) A review of phylogenetic and metabolic relationships between the acylamino acids, N-acetyl-L-aspartic acid and N-acetyl-L-histidine in the vertebrate nervous system. J. Neurochem. 68(4), 1335-1344.
4. Baslow M. H. and Resnik T.R. (1997) Canavan disease: Analysis of the nature of the metabolic lesions responsible for development of the observed clinical symptoms. J. Mol. Neurosci. 9(2), 109-126.
5. Baslow M. H. (1998) Function of the N-acetyl-L-histidine system in the vertebrate eye. Evidence in support of a role as a molecular water pump. J. Mol. Neurosci. 10(3), 193-208.
6. Baslow M. H. (1999a) Molecular water pumps and the etiology of Canavan disease; a case of the sorcerer's apprentice. J. Inherited Metab. Dis. 22, 99-101.
7. Baslow M. H. (1999b) The existence of molecular water pumps in the nervous system. A review of the evidence. Neurochem. Int. 34, 77-90.
8. Baslow M. H. and Resnik T. R. (1999) Molecular water pumps in the central nervous system and their role in neuropathology. Recent Res. Dev. Neurochem. 2, 15-23.
9. Baslow M. H. and Yamada S. (1997) Identification of N-Acetylaspartate in the lens of the vertebrate eye: a new model for the investigation of the function of N-acetylated amino acids in vertebrates. Exp. Eye Res. 64(2), 283-286.
10. Bates T. E., Strangward M., Keelan J., Davey G. P., Munro P. M., and Clark J. B. (1996) Inhibition of N-acetylaspartate production: implications for 1H MRS studies in vivo. Neuroreport 7(8), 1397-1400.
11. 1H-NMR spectroscopic studies of brain. Neurosci. Biobehav. Rev. 13, 23-31.
12. Brockmann K., Pouwels P. J. W., Christen H.-J., Frahm J., and Hanefeld F. (1996) Localized proton magnetic resonance spectroscopy of cerebral metabolic disturbances in children with neuronal ceroid lipofuscinosis. Neuropediatrics 27, 242-248.
13. D'Adamo A. F. Jr., Smith J. C., and Weiler C. (1973) The occurrence of N-acetylaspartate aminohydrolase (aminoacylase II) in the developing rat. J. Neurochem. 20, 1275-1278.
14. During, M. (1996) Gene therapy in New Zealand [letter]. Science 272, 467.
15. Goldstein F. B. (1976) Amidohydrolases of the brain: enzymatic hydrolysis of N-acetyl-L-aspartate and other N-acyl-L-amino acids. J. Neurochem. 26, 45-49.
16. Kaul R., Casanova J., Johnson A. B., Tang P., and Matalon R. (1991) Purification, characterization, and localization of aspartoacylase from bovine brain. J. Neurochem. 56, 129-135.
17. Kaul R., Balamurugan K., Gao G. P., and Matalon R. (1994) Canavan disease: Genomic organization and localization of human ASPA to 17p13-ter and conservation of the ASPA gene during evolution. Genomics 21, 364-370.
18. McCarthy K. D. and De Vellis J. (1980) Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J. Cell. Biol. 85, 890-902.
19. +-glucose cotransporter is a molecular water pump. J. Physiol. 508(1), 15-21.
20. Sakamoto K., Murata T., Omori M., Kimura H., Nishio M., et al. (1998) Clinical studies on three cases of the interval form of carbon monoxide poisoning: serial proton magnetic resonance spectroscopy as a prognostic predictor. Psychiat. Res. 83, 179-192.
21. Simmons M. L., Frondoza C. G., and Coyle J. T. (1991) Immunocytochemical localization of N-acetyl-aspartate with monoclonal antibodies. Neuroscience 45(1), 37-45.
22. Urenjak J., Williams S. R., Gadian D. G., and Noble M. (1992) Specific expression of N-acetyl-aspartate in neurons,oligodendrocyte-type-2 astrocyte progenitors, and immature oligodendrocytes in vitro. J. Neurochem. 59, 55-61.
23. Waksman B. H. (1999) Demyelinating disease: Evolution of a paradigm. Neurochem. Res. 24(4), 491-495.
24. Wolman M. (1958) The spongy type of diffuse sclerosis. Brain 81, 243-247.