-
1
-
-
0015237292
-
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin like drugs
-
Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin like drugs. Nature (New Biol) 1971; 231: 23-235.
-
(1971)
Nature (New Biol)
, vol.231
, pp. 23-235
-
-
Vane, J.R.1
-
2
-
-
0015237275
-
Aspirin selectively inhibits prostaglandin production in human platelets
-
Smith JH, Willis AL. Aspirin selectively inhibits prostaglandin production in human platelets. Nature (New Biol) 1971; 231: 235-237.
-
(1971)
Nature (New Biol)
, vol.231
, pp. 235-237
-
-
Smith, J.H.1
Willis, A.L.2
-
3
-
-
0023854087
-
Regulation of fibroblast cyclooxygenase synthesis by interleukin-1
-
Raz A, Wyche A, Siegel N, Needleman P. Regulation of fibroblast cyclooxygenase synthesis by interleukin-1. J Biol Chem 1988; 263: 3022-3028.
-
(1988)
J Biol Chem
, vol.263
, pp. 3022-3028
-
-
Raz, A.1
Wyche, A.2
Siegel, N.3
Needleman, P.4
-
5
-
-
0028322893
-
Selective inhibition of inducible cyclooxygenase 2 in vivo is anti-inflammatory and nonulcerogenic
-
Masferrer JL, Zweifel BS, Manning PT, Hauser DS, Leahy KM, Smith WG, Isakson PC, Seibert K. Selective inhibition of inducible cyclooxygenase 2 in vivo is anti-inflammatory and nonulcerogenic. Proc Natl Acad Sci USA 1994; 91: 3228-3232.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3228-3232
-
-
Masferrer, J.L.1
Zweifel, B.S.2
Manning, P.T.3
Hauser, D.S.4
Leahy, K.M.5
Smith, W.G.6
Isakson, P.C.7
Seibert, K.8
-
6
-
-
0027944075
-
Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain
-
Seibert K, Zhang Y, Lehy K, Hauser S, Masferrer J, Perkins W, Lee L, Isakson P. Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc Natl Acad Sci USA 1994; 91: 12013-12017.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12013-12017
-
-
Seibert, K.1
Zhang, Y.2
Lehy, K.3
Hauser, S.4
Masferrer, J.5
Perkins, W.6
Lee, L.7
Isakson, P.8
-
7
-
-
13444266910
-
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]bezenesulfonamide (SC-58635, celecoxib)
-
Penning TD, Talley JJ, Bertenshaw SR., Carter JD, Collins PW, Docter S, Graneto, MJ, Lee LF, Malecha JW, Miyashiro JM, Rogers RS, Rogier DJ, Yu SS, Anderson GD, Burton EG, Cogburn JN, Gregory SA, Koboldt CM, Perkins WE, Seibert K, Veenhuizen AW, Zhang YY, Isakson PC. Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]bezenesulfonamide (SC-58635, celecoxib). J Med Chem 1997; 40: 1347-1365.
-
(1997)
J Med Chem
, vol.40
, pp. 1347-1365
-
-
Penning, T.D.1
Talley, J.J.2
Bertenshaw, S.R.3
Carter, J.D.4
Collins, P.W.5
Docter, S.6
Graneto, M.J.7
Lee, L.F.8
Malecha, J.W.9
Miyashiro, J.M.10
Rogers, R.S.11
Rogier, D.J.12
Yu, S.S.13
Anderson, G.D.14
Burton, E.G.15
Cogburn, J.N.16
Gregory, S.A.17
Koboldt, C.M.18
Perkins, W.E.19
Seibert, K.20
Veenhuizen, A.W.21
Zhang, Y.Y.22
Isakson, P.C.23
more..
-
8
-
-
0000949266
-
Specific COX-2 inhibitors: From bench to bedside
-
Vane J, Botting J (eds), London: J. Kluwer Academic Publishers and William Harvey Press
-
Isakson P, Zweifel B, Masferrer J, Koboldt C, Seibert K, Hubbard R, Geis S, Needleman P. Specific COX-2 inhibitors: from bench to bedside. In: Vane J, Botting J (eds), Selective COX-2 Inhibitors: Pharmacology, Clinical Effects and Therapeutic Potential. London: J. Kluwer Academic Publishers and William Harvey Press, 1998; 127-133.
-
(1998)
Selective COX-2 Inhibitors: Pharmacology, Clinical Effects and Therapeutic Potential
, pp. 127-133
-
-
Isakson, P.1
Zweifel, B.2
Masferrer, J.3
Koboldt, C.4
Seibert, K.5
Hubbard, R.6
Geis, S.7
Needleman, P.8
-
9
-
-
0027275566
-
Physiological parameters in laboratory animals and humans
-
Davies B, Morris T. Physiological parameters in laboratory animals and humans. Pharm Res 1993; 10: 1093-1095.
-
(1993)
Pharm Res
, vol.10
, pp. 1093-1095
-
-
Davies, B.1
Morris, T.2
-
11
-
-
0018871184
-
Plasma protein binding and therapeutic drug monitoring
-
Rowland M. Plasma protein binding and therapeutic drug monitoring. Ther Drug Monit 1980; 2: 29-37.
-
(1980)
Ther Drug Monit
, vol.2
, pp. 29-37
-
-
Rowland, M.1
-
12
-
-
0026457029
-
Methods of determining plasma and tissue binding of drugs
-
Pacifici GM, Viani A. Methods of determining plasma and tissue binding of drugs. Clin Pharmacokinet 1992; 23: 449-468.
-
(1992)
Clin Pharmacokinet
, vol.23
, pp. 449-468
-
-
Pacifici, G.M.1
Viani, A.2
-
13
-
-
0023020004
-
The plasma protein binding of basic drugs
-
Routledge PA. The plasma protein binding of basic drugs. Br J Clin Pharmacol 1986; 22: 499-506.
-
(1986)
Br J Clin Pharmacol
, vol.22
, pp. 499-506
-
-
Routledge, P.A.1
-
14
-
-
0028942901
-
What is the true clinical significance of plasma protein binding displacement interactions?
-
Sansom LN, Evans AM. What is the true clinical significance of plasma protein binding displacement interactions? Drug Safety 1995; 12: 227-233.
-
(1995)
Drug Safety
, vol.12
, pp. 227-233
-
-
Sansom, L.N.1
Evans, A.M.2
-
15
-
-
0001693587
-
Preclinical pharmacologyof celecoxib and demonstration of superior GI safety compared with NSAIDs in dogs
-
Maziasz TJ, Seibert K, Khan NK, Paulson SK, Isakson PC. Preclinical pharmacologyof celecoxib and demonstration of superior GI safety compared with NSAIDs in dogs. Arthritis Rheum 1997; 40: S195.
-
(1997)
Arthritis Rheum
, vol.40
-
-
Maziasz, T.J.1
Seibert, K.2
Khan, N.K.3
Paulson, S.K.4
Isakson, P.C.5
|