Antifungal mechanism of a cysteine-rich antimicrobial peptide, Ib-AMP1, from Impatiens balsamina against Candida albicans

Biotechnology Letters

Volumn 21, Issue 12, 1999, Pages 1047-1050

  Lee, Dong Gun ^a   Shin, Song Yub ^a   Kim, Dae Hee ^b   Seo, Moo Yeol ^a   Kang, Joo Hyun ^a   Lee, Younghoon ^b   Kim, Kil Lyong ^a   Hahm, Kyung Soo ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Antifungal mechanism; Candida albicans; Confocal microscopy; Ib AMP1

Indexed keywords

CECROPIN; CYSTEINE; DISULFIDE; MAGAININ 2; PEPTIDE; PHOSPHOLIPID;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS FLAVUS; CANDIDA ALBICANS; CELL MEMBRANE; CELL SURFACE; CHANNEL GATING; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ION CHANNEL; NONHUMAN; PROTEIN BINDING;

ASPERGILLUS FLAVUS; CANDIDA ALBICANS; IMPATIENS BALSAMINA;

EID: 0033383178     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005636610512     Document Type: Article

References (10)

1. García-Olmedo F, Molina A, Alamillo JM, Rodríguez-Palenzula P (1998) Plant defense peptides. Biopolymers (Peptide Science) 47: 479-491.
2. Kang JH, Shin SY, Lee MK, Hahm K-S (1998) Release of aqueous contents from phospholipid vesicles induced by cecropin A(1-8)-magainin 2(1-12) hybrid and its analogues. J. Peptide Res. 52: 45-50.
3. MacDonald RC, MacDonald RI, Menco BP, Takeshita K, Subbarao NK, Hu L-r (1991) Small-volume extrusion apparatus for preparation of large, unilamellar vesicles. Biochim. Biophys. Acta 1061: 297-303.
4. Merrifield RB (1986) Solid phase synthesis. Science 232: 341-347.
5. Osborn RW, De Samblanx GW, Thevissen K, Goderis I, Torrekens S, Van Leuven F, Attenborough S, Rees SB (1995) Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae. FEBS Lett. 368: 257-262.
6. Patel SU, Osborn R, Rees S, Thornton JM (1998) Structural studies of Impatiens balsamina antimicrobial protein (Ib-AMP1). Biochemistry 37: 983-990.
7. Shin SY, Watanabe M, Kako K, Ohtaki T, Munekata E (1994) Structure-activity relationships of human epidermal growth factor (h-EGF). Life Sci. 55: 131-139.
8. Shin SY, Lee MK, Kim KL, Hahm K-S (1997) Structure-antitumor and hemolytic activity relationships of synthetic peptides derived from cecropin A-magainin 2 and cecropin A-melittin hybrid peptides. J. Peptide Res. 50: 279-285.
9. Shin SY, Kang JH, Hahm K-S (1999) Structure-antibacterial, antitumor and hemolytic activity relationships of cecropin A-magainin 2 and cecropin A-melittin hybrid peptides. J. Peptide Res. 53: 82-90.
10. Tailor RH, Acland DP, Attenborough S, Cammue BPA, Evans IJ, Osborn RW, Ray JA, Rees SB, Broekaert WF (1997) A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein. J. Biol Chem. 272: 24480-24487.