Insulin-like growth factor binding protein (IGFBP)-3-Bound IGF-I and IGFBP-3-Bound IGF-II in growth hormone deficiency

Hormone Research

Volumn 52, Issue 2, 1999, Pages 60-65

  Belgorosky, Alicia ^a,b   Rivarola, Marco A ^a  

^a Hospital de Pediatria SAMIC Prof Dr Juan P Garrahan   (Argentina)

^b HOSPITAL DE PEDIATRÍA PROF DR JUAN P GARRAHAN   (Argentina)

Author keywords

Growth hormone deficiency; Insulin like growth factor binding protein 3; Insulin like growth factors I and II

Indexed keywords

GROWTH HORMONE; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN BINDING PROTEIN 4; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN BINDING PROTEIN 6; SOMATOMEDIN C; SOMATOMEDIN RECEPTOR;

ADOLESCENT; ARTICLE; BLOOD ANALYSIS; CHILD; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEVICE; FEMALE; GROWTH HORMONE DEFICIENCY; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION;

EID: 0033381320     PISSN: 03010163     EISSN: None     Source Type: Journal    
DOI: 10.1159/000023436     Document Type: Article

References (36)

1. Rosenfeld RG, Albertsson-Wikland K, Cassorla F, Reasier SD, Hasegawa Y, Hintz RL, Lafranchi S, Lippe B, Loriaux L, Melmed S, Preece M, Ranke M, Reiter EO, Rogol AD, Underwood LE, Wherter GA: Diagnostic controversy: The diagnosis of childhood growth hormone deficiency revisited. J Clin Endocrinol Metab 1995;80:1532-1540.
2. Rikken B, van Doorn J, Ringeling A, Van den Branden JL, Massa G, Wit JM: Plasma levels of insulin-like growth factor (IGF)-I, IGF-II and IGF-binding protein-3 in the evaluation of childhood growth hormone deficiency. Horm Res 1998;50:166-176.
3. Jones JI, Clemmons DR: Insulin-like growth factors and their binding proteins: Biological actions. Endocr Rev 1995;16:3-34.
4. Twigg SM, Baxter RC: Insulin-like growth factor (IGF)-binding protein 5 forms an alternative ternary complex with IGFs and the acid-labile subunit. J Biol Chem 1998;273:6074-6079.
5. Baxter RC, Martin JL, Beniac BA: High molecular weight insulin-like growth factor binding protein complex: Purification and properties of the acid-labile subunit from human serum. J Biol Chem 1989;264:11843-11848.
6. Guler H-P, Zapf J, Schmid C, Froesch ER: Insulin-like growth factors I and II in healthy man. Estimations of half-lives and production rates. Acta Endocrinol (Copenh) 1989;121: 753-758.
7. Lewitt MS, Saunders H, Phuyal JL, Baxter RC: Complex formation by human insulin-like growth factor binding protein-3 and human acid-labile subunit in growth hormone deficient rats. Endocrinology 1994;134:2404-2409.
8. Young SCJ, Miles MV, Clemmons DR: Determination of the pharmacokinetic profiles of insulin-like growth factor binding proteins-1 and -2 in rats. Endocrinology 1992;131:1867-1873.
9. Baxter RC: Circulating binding proteins for the insulin-like growth factors. Trends Endocrinol Metab 1993;4:91-96.
10. Rajaram S, Baylink DJ, Mohan S: Insulin-like growth factor-binding proteins in serum and other biological fluids: Regulation and functions. Endocr Rev 1997;18:801-831.
11. Oh Y, Muller HL, Lamson G, Rosenfeld RG: Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. J Biol Chem 1993;268: 14964-14971.
12. Lalou C, Lasarre C, Binoux M: A proteolytic fragment of insulin like growth factor (IGF) binding protein-3 that fails to bind IGFs inhibits the mitogenic effects of IGF-I and insulin. Endocrinology 1996;137:3206-3212.
13. Ranke MB, Elmlinger M: Functional role of insulin-like growth factor binding proteins. Horm Res 1997:48(suppl 4):9-15.
14. Hasegawa Y: Clinical utility of free insulin-like growth factor-I levels during childhood. J Endocrinol Invest 1998;21:101-104.
15. Takada M, Nakanome H, Kishida M, Hirose S, Hasegawa T, Hasegawa Y: Measurement of free insulin-like growth factor-I using immunoradiometric assay. J Immunoassay 1994;15: 263-276.
16. Frystyk J, Skjaerback C, Dinesen B, Orskov H: Free insulin-like growth factors (IGF-I and IGF-II) in human serum. FEBS Lett 1994;348: 185-191.
17. Juul A, Holm K. Kastrup KW, Pedersen SA, Michaelsen KF, Scheike T, Rasmussen S, Muller J, Skakkebaek EN: Free insulin-like growth factor I serum levels in 1430 healthy children and adults, and its diagnostic value in patients suspected of growth hormone deficiency. J Clin Endocrinol Metab 1997;82:2497-2502.
18. Hasegawa Y, Takada M, Hasegawa T, Tsuchiya Y: Clinical utility of newly developed free insulin-like growth factor-I measurements in the diagnosis of growth hormone deficiency in children and adolescents. Eur J Endocrinol 1996;134:184-189
19. Holly JMP, Claffey DCP, Cwyfan-Hughes SC, Frost VT, Yateman ME: Protease acting on IGFBPs: Their occurrence and physiological significance. Growth Regul 1993;3:88-91.
20. Clemmons DR, Busby WH, Arai T, Clarke JB, Jones JI, Ankrapp DK: Role of growth factor binding protein in the control of IGF-I actions. Prog Growth Factor Res 1995;6:357-366.
21. Holly JMP, Maile LA, Whellams EJ: Insulin-like growth factor binding protein proteases in vivo. J Endocrinol Invest 1998;21:93-100.
22. Juul A, Dalgaard P, Blum WF, Bang P, Hall K, Michaelson KF, Muller J, Skakkebaek EN: Serum levels of insulin-like growth factor (IGF) binding protein-3 (IGFBP-3) in healthy infants, children, and adolescents: The relation to IGF-I, IGF-II, IGFBP-1, IGFBP-2, age, sex, body mass index, and pubertal maturation. J Clin Endocrinol Metab 1995;80:2534-2542.
23. Ciaccio M, Rivarola MA, Belgorosky A: Differences in insulin-like growth factor-I and sex hormone binding globulin levels between late and early prepuberty in patients with idiopathic and organic growth hormone deficiency. Acta Endocrinol (Copenh) 1993;129:419-423.
24. Belgorosky A, Escobar ME, Rivarola MA: Validity of the calculation of nonsex hormone-binding globulin-bound estradiol from total testosterone, total estradiol and sex hormone binding globulin concentrations in human serum. J Steroid Biochem 1987;28:429-432.
25. Belgorosky A, Rivarola MA: Progressive increase in nonsex hormone-binding globulin-bound testosterone and estradiol from infancy to late prepuberty in girls. J Clin Endocrinol Metab 1988;67:234-237.
26. Belgorosky A, Rivarola MA: Determination of albumin-bound thyroxine in human serum. Clin Chem 1990;36:699.
27. Belgorosky A, Weller G, Chaler E, Iorcansky S, Rivarola MA: Evaluation of serum total thyroxine, and triiodothyronine, and their serum fractions, in nonthyroidal illness secondary to congenital heart disease. Studies before and after surgery. J Endocrinol Invest 1993;16: 499-503.
28. Bach LA, Hsieh S, Sakano K, Fuyiwara H, Perdue J, Rechler M: Binding of mutants of human insulin-like growth factor II to insulin-like growth factor binding proteins 1-6. J Biol Chem 1993;268:9246-9254.
29. Skjacrbaek C, Kaal A, Moller J, Vahl N, Weeke J, Orskov H, Flyvbjerg A: No effect of growth hormone on serum insulin-like growth factor binding protein-3 proteolysis. J Clin Endocrinol Metab 1998;83:1206-1210.
30. Honda Y, Landale EC, Strong DD, Baylink DJ, Mohan S: Recombinant synthesis of insulin-like growth factor binding protein-4 (IGFBP-4): Development, validation, and application of a radioimmunoassay for IGFBP-4 in human serum and other biological fluids. J Clin Endocrinol Metab 1996;81:1389-1396.
31. Baxter RC, Saunders H: Radioimmunoassay of insulin-like growth factor binding protein-6 in human serum and other body fluids. J Endocrinol 1992;134:133-139.
32. Mohan S, Libanati C, Dony C, Lang K, Srinivasan N, Baylink DJ: Development, validation, and application of a radioimmunoassay for insulin-like growth factor binding protein-5 in human serum and other biological fluids. J Clin Endocrinol Metabol 1995;80:2638-2645.
33. Kim H-S, Nagalla SR, Oh Y, Wilson E, Robert Jr CT, Rosenfeld RG: Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of IGFBP superfamily. Proc Natl Acad Sci USA 1997;94:12981-12986.
34. Holman SR, Baxter RC: Insulin-like growth factor binding protein-3: Factors affecting binary and ternary complex formation. Growth Regul 1996;6:42-47.
35. Rosenthal SM, Hsiao D, Silverman LA: An insulin-like growth factor-II (IGF-II) analog with highly selective affinity for IGF-II receptors stimulates differentiation, but not IGF-I receptor down-regulation, in muscle cells. Endocrinology 1994;135:38-44.
36. Powell DR, Durham SK, Liu F, Baker BK, Lee PDK, Watkins SL, Campbell PG, Brewer DE, Hintz RL, Hogg RJ: The insulin-like growth factor axis and growth in children with chronic-renal failure: A report of the Southwest Pediatric Nephrology Study Group. J Clin Endocrinol Metab 1998;83:1654-1661.