Calcineurin phosphatase inhibitors, tacrolimus and cyclosporine, potentiate vasopressin V2 receptor mediated effects on locomotor and analgesic activity in mice

Pharmacology Reviews and Communications

Volumn 10, Issue 4, 1999, Pages 265-270

  Tyagi, M G ^a   Jose, V M ^a  

^a CHRISTIAN MEDICAL COLLEGE   (India)

Author keywords

Analgesic; Calcineurin; Locomotor; Vasopressin

Indexed keywords

ACETIC ACID; CALCINEURIN PHOSPHATASE INHIBITOR; CYCLOSPORIN; DESMOPRESSIN; ENZYME INHIBITOR; IMMUNOPHILIN; IMMUNOSUPPRESSIVE AGENT; TACROLIMUS; UNCLASSIFIED DRUG; VASOPRESSIN V2 RECEPTOR;

ANALGESIA; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; FEMALE; LOCOMOTION; MALE; MOUSE; NONHUMAN; OPEN FIELD BEHAVIOR; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WRITHING TEST;

EID: 0033381137     PISSN: 10288945     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Antoni, F.A.(1984) Novel ligand specificity of pituitary vasopressin receptors in the rat. Neuroendocrinol. 39, 186-188.
2. Brinton, R.E and Brownson E.A. (1993). Vasopressin induction of cyclic AMP in cultured hippocampal neurons. Dev Brain.Res. 71, 101-105.
3. Cheng, S.W.T and North, W.G (1989) Vasopressin reduces release from Vasopressin - neurons and oxytocin neurons by acting on V2 like receptors. Brain Res. 479,35-39.
4. Chiu J, Kalant H., Le D.A. (1998) Vasopressin opposes locomotor stimulation by ethanol, Cocaine and amphetamine in mice. Eur. J Pharmacol. 355, 11-17.
5. 2 receptor subtype in the central nervous System. Brain Res. 759, 13-23.
6. Dawson, T.M., Steiner J.P., Lyons, W.E., Fotuhi, M, Blue M, and Snyder, S.H. (1994). The immunophilins, FK506 binding protein and cyclophilin, are discretely localised in the brain; relationship to calcineurin, Neuroscience, 62(2), 569-580.
7. De Wied D, Diamant, M., and Fodor, M (1993) Central nervous system effects of the neurohypophyseal hormones and related peptides, Front Neuroendocrinol. 14, 251-302.
8. Di Michele, S., Sillen, U., Engel, J.A., Hjalmas, K., Rubenson, A., Soderpalm, B (1996) Desmopressin and vasopressin increase locomotor activity in the rat via a central mechanism: implications for nocturnal enuresis. J. Urol. 156, 1161-1168.
9. Elands, J., De Kloet, E.R and De Wied D (1992) Neurohypophyseal hormone receptors, relation to behavior. Prog. Brain. Ras. 91, 459-464.
10. Isobe Y, and Nishino, H (1998) AVP rhythm in the suprachiasmatic nucleus in relation to locomotor activity under constant light. Peptides, 19, 5, 827-832.
11. 2- - dependent Phosphatase., Nature, 369, 235-239.
12. Liu, J., Farmer, J.D.Jr., Lane, W.S., Friedman J., Weissman, I and Schreiber, S.L (1991) Calcineurin is a common target of cyclophilin - cyclosporine A and FKBP - FK 506 complexes. Cell, 66, 807-815.
13. Lolait, S., O' Carroll, A.M , McBride, O.W., Konig, M., Morel, A., and Browstein, M.J.(1992) Cloning and characterization of a vasopressin V2 receptor and possible Link to nephrogenic Diabetes Insipidus. Nature, 357: 336-339.
14. Ramaswamy, S., Shewade, D.G , Tyagi., M.G., and Bapna, J.S (1992) Further studies on the antinociceptive effects of vasopressin. J. Pharm Pharmacol. 44, 698-700.
15. Salamone, J.D (1992) Complex motor and sensorimotor functions of striatal and nucleus accumbens dopamine: involvement in instrumental behavior processes. Psychopharmacol. (Berlin), 107: 160.
16. Schreiber, S.L and Crabtree, G.R (1992) The mechanism of action of Cyclosporine A and FK506. Immun. Today 13, 136-142.
17. Steiner J.P., Dawson, T.M., Fotuhi M., Glatt, C.E., Snorman A.M., Cohen, N and Snyder, S.H (1992) High brain densities of the immunophilin FKBP colocalized with Calcineurin Nature 358, 584-587.
18. Swanson, S.K.H., Born, T., Zydowsky, L.D., Cho, H., Chang, H.Y., Walsh, C.T and Rusnak, F (1992) Cyclosporine mediated inhibition of bovine calcineurin by cyclophilins A & B. Proc Natn. Acad. Sci. USA, 89, 3741-3745.
19. Thibonnier, M., Bayer, A.L., and Leng Z. (1993) Cytoplasmic and nuclear signaling pathways of V1 vasopressin receptors. Regul. Peptides. 45: 79-84.
20. Tong G, Shepherd, D and Jahr C.E (1995) Synaptic desensitization of NMDA receptor by calcineurin. Science, 267, 1510-1512.
21. Torii, N., Kamishita, T., Otsu, Y and Tsumoto, T. (1995) An inhibitor for calcineurin, FK506 blocks induction of long term depression in rat visual cortex. Neurosci. Lett. 185, 1-4.
22. Tyagi, M.G., Ramaswamy, S., Shewade, D.G and Tripathi, K.D (1992) Vasopressin acts independently of calcium to induce analgesia in mice. Med. Sci. Res. 20, 131-132.
23. Tyagi, M.G., Handa, R.K., Stephen, P.M., Bapna, J.S. (1998) Vasopressin induces dopamine release and cyclic AMP efflux from the brain of water deprived rats; Inhibitory effect of Vasopressin V2 receptor mediated phosphorylation. Biol. Sig Rec 7: 328-336.