Assignment of ACVR2 and ACVR2B the human activin receptor type II and IIB genes to chromosome bands 2q22.2→q23.3 and 3p22 and the human follistatin gene (FST) to chromosome 5q11.2 by FISH

Cytogenetics and Cell Genetics

Volumn 87, Issue 3-4, 1999, Pages 219-220

  Bondestam, Jonas ^b   Horelli Kuitunen, N ^a   Hilden K ^c   Ritvos, O ^c   Aaltonen, J ^c  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; ACTIVIN RECEPTOR; FOLLISTATIN;

ARTICLE; CHROMOSOME 2Q; CHROMOSOME 3P; CHROMOSOME 5Q; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECEPTOR GENE;

ACTIVIN RECEPTORS, TYPE II; CHROMOSOMES, HUMAN, PAIR 2; CHROMOSOMES, HUMAN, PAIR 3; CHROMOSOMES, HUMAN, PAIR 5; FOLLISTATIN; GLYCOPROTEINS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PHYSICAL CHROMOSOME MAPPING; RECEPTORS, GROWTH FACTOR;

EID: 0033379718     PISSN: 03010171     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Heiskanen M, Kallioniemi OP, Palotie A; Fiber-FISH: Experiences and a refined protocol. Genet Anal Biol Eng 12:179-184 (1996).
2. Ishikawa S, Kai M, Murata Y, Tamari M, Daigo Y, Murano T, Ogawa M, Nakamura Y: Genomic organization and mapping of the human activin receptor type IIB (hActR-IIB) gene. J hum Genet 42:132-134 (1998).
3. Kosaki R, Gebbia M, Kosaki K, Lewin M, Bowers P, Towbin JA, Casey B: Left-right malformations associated with mutations in ACVR2B, the gene for human activin receptor type IIB. Am J med Genet 82:70-76 (1999).
4. Lemieux NM, Dutrillaux B, Viegas-Péquignot E: A simple method for simultaneous R- or G-banding and fluorescence in situ hybridization of small single-copy genes. Cytogenet Cell Genet 59:311-312 (1992).
5. Lichter P, Cremer T, Tang CJ, Watkins P, Manuelidis L, Ward DC: Rapid detection of human chromosome 21 aberration by in situ hybridization. Proc natl Acad Sci. USA 85:9664-9668 (1988).
6. Matzuk M, Kumar R, Bradley A: Different phenotypes for mice deficient in either activins or activin receptor type II. Nature 374:356-360 (1995a).
7. Matzuk M, Lu N, Vogel H, Sellheyer K, Roop D, Bradley A: Multiple defects and perinatal death in mice deficient in follistatin. Nature 374:360-363 (1995b).
8. Oh S, Li E: The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse. Genes Dev 11:1812-1826 (1997).
9. Pinkel, D. Straume T, Gray J: Cytogenetic analysis using quantitative, high sensitivity, fluorescence hybridization. Proc natl Acad Sci. USA 83:2934-2938 (1986).