메뉴 건너뛰기




Volumn 31, Issue 2, 1999, Pages 133-145

Factors involved in the pathogenesis of neutrophilic vasculitis in MRL/Mp-lpr/lpr mice: A model for human microscopic angiitis

Author keywords

ANCA; Cytokines; Endothelium; MRL; Myeloperoxidase; Vasculitis

Indexed keywords

AUTOANTIBODY; MYELOPEROXIDASE; NEUTROPHIL CYTOPLASMIC ANTIBODY;

EID: 0033378497     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939908994057     Document Type: Article
Times cited : (5)

References (39)
  • 1
    • 0023279838 scopus 로고
    • Prospective study of radioimmunoassay for antibodies against neutrophil cytoplasm in diagnosis of systemic vasculitis
    • Savage, C.O.S., Winearls, C.G., Jones, S., Marshall, P.D. and Lockwood, C.M. Prospective study of radioimmunoassay for antibodies against neutrophil cytoplasm in diagnosis of systemic vasculitis. Lancet 1987, i: 1389-93.
    • (1987) Lancet , vol.1 , pp. 1389-1393
    • Savage, C.O.S.1    Winearls, C.G.2    Jones, S.3    Marshall, P.D.4    Lockwood, C.M.5
  • 2
    • 0023878734 scopus 로고
    • Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis
    • Falk, R.J. and Jennette, J.C. Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N. Engl. J. Med. 1988, 318: 1651-57.
    • (1988) N. Engl. J. Med. , vol.318 , pp. 1651-1657
    • Falk, R.J.1    Jennette, J.C.2
  • 3
    • 0025943882 scopus 로고
    • Anti-neutrophil cytoplasmic autoantibody associated diseases: A pathologist's perspective
    • Jennette, J.C. Anti-neutrophil cytoplasmic autoantibody associated diseases: a pathologist's perspective. Am. J. Kid. Dis. 1991, 18: 164-70.
    • (1991) Am. J. Kid. Dis. , vol.18 , pp. 164-170
    • Jennette, J.C.1
  • 4
    • 0028158243 scopus 로고
    • Nomenclature of systemic vasculitides. Proposal of an international consensus conference
    • Jennette, J.C., Falk, R.J., Andrassy, K., Bacon, P.A., Churg, J. and Gross, W.L. et al. Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis Rheum. 1994, 37: 187-92.
    • (1994) Arthritis Rheum. , vol.37 , pp. 187-192
    • Jennette, J.C.1    Falk, R.J.2    Andrassy, K.3    Bacon, P.A.4    Churg, J.5    Gross, W.L.6
  • 5
    • 0026501713 scopus 로고
    • Anti-myeloperoxidase antibodies stimulate neutrophils to damage human endothelial cells
    • Ewert, B.H., Jennette, J.C. and Falk, R.J. Anti-myeloperoxidase antibodies stimulate neutrophils to damage human endothelial cells. Kid. Int. 1992, 41: 375-83.
    • (1992) Kid. Int. , vol.41 , pp. 375-383
    • Ewert, B.H.1    Jennette, J.C.2    Falk, R.J.3
  • 6
    • 0026705320 scopus 로고
    • Autoantibodies developing to myeloperoxidase and proteinase 3 in systemic vasculitis stimulate neutrophil cytotoxicity toward cultured endothelial cells
    • Savage, C.O., Pottinger, B.E., Gaskin, G., Pusey, C.D. and Pearson, J.D. Autoantibodies developing to myeloperoxidase and proteinase 3 in systemic vasculitis stimulate neutrophil cytotoxicity toward cultured endothelial cells. Am. J. Pathol. 1992, 141: 335-42.
    • (1992) Am. J. Pathol. , vol.141 , pp. 335-342
    • Savage, C.O.1    Pottinger, B.E.2    Gaskin, G.3    Pusey, C.D.4    Pearson, J.D.5
  • 7
    • 0022195245 scopus 로고
    • Two histopathologic types of inflammatory vascular disease in MRL/Mp autoimmune mice
    • Alexander, E.L., Moyer, C.M., Travlos, G.S., Roths, J.B. and Murphy, E.D. Two histopathologic types of inflammatory vascular disease in MRL/Mp autoimmune mice. Arthritis Rheum. 1985, 28: 1146-55.
    • (1985) Arthritis Rheum. , vol.28 , pp. 1146-1155
    • Alexander, E.L.1    Moyer, C.M.2    Travlos, G.S.3    Roths, J.B.4    Murphy, E.D.5
  • 8
    • 0023263474 scopus 로고
    • Systemic mononuclear-cell vasculitis in MRL/Mp-lpr/lpr mice
    • Moyer, C.M., Strandberg, J.D. and Reinisch, C.L. Systemic mononuclear-cell vasculitis in MRL/Mp-lpr/lpr mice. Am. J. Pathol. 1987, 127: 229-41.
    • (1987) Am. J. Pathol. , vol.127 , pp. 229-241
    • Moyer, C.M.1    Strandberg, J.D.2    Reinisch, C.L.3
  • 9
    • 0027481688 scopus 로고
    • Genetic selection for crescentic formation yields mouse strain with rapidly progressive glomerulonephritis and small vessel vasculitis
    • Kinjoh, K., Kyogoku, M. and Good, R.A. Genetic selection for crescentic formation yields mouse strain with rapidly progressive glomerulonephritis and small vessel vasculitis. Proc. Natl. Acad. Sci. USA 1993, 90: 3413-17.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3413-3417
    • Kinjoh, K.1    Kyogoku, M.2    Good, R.A.3
  • 10
    • 0026734809 scopus 로고
    • Mercuric chloride-treated Brown Norway rats develop widespread tissue injury including necrotizing vasculitis
    • Mathieson, P.W., Thiru, S. and Oliveira, D.B.G. Mercuric chloride-treated Brown Norway rats develop widespread tissue injury including necrotizing vasculitis. Lab. Invest. 1992, 67: 121-9.
    • (1992) Lab. Invest. , vol.67 , pp. 121-129
    • Mathieson, P.W.1    Thiru, S.2    Oliveira, D.B.G.3
  • 11
    • 0026766721 scopus 로고
    • Autoantibodies to myeloperoxidase in Brown Norway rats treated with mercuric chloride
    • Esnault, V.L.M., Mathieson, P.W., Thiru, S., Oliveira, D.B.G. and Lockwood, C.M. Autoantibodies to myeloperoxidase in Brown Norway rats treated with mercuric chloride. Lab. Invest. 1992, 67: 114-20.
    • (1992) Lab. Invest. , vol.67 , pp. 114-120
    • Esnault, V.L.M.1    Mathieson, P.W.2    Thiru, S.3    Oliveira, D.B.G.4    Lockwood, C.M.5
  • 12
    • 0001787482 scopus 로고
    • Hybridomas from SCG/Kj mice produce p-ANCA with specificity for myeloperoxidase (MPO) and induce proteinuria in nude mice
    • Kinjoh, K., Good, R.A., Taylor, J., Nachman, P., Falk, R.J. and Jennette, J.C. Hybridomas from SCG/Kj mice produce p-ANCA with specificity for myeloperoxidase (MPO) and induce proteinuria in nude mice. Clin. Exp. Immunol. 1995, 101 (Suppl. 1): 37.
    • (1995) Clin. Exp. Immunol. , vol.101 , Issue.SUPPL. 1 , pp. 37
    • Kinjoh, K.1    Good, R.A.2    Taylor, J.3    Nachman, P.4    Falk, R.J.5    Jennette, J.C.6
  • 14
    • 0031875778 scopus 로고    scopus 로고
    • Myeloperoxidase autoantibodies distinguish vasculitis mediated by anti-neutrophil cytoplasm antibodies from immune complex disease in MRL/Mp-lpr/lpr mice: A spontaneous model for human microscopic angiitis
    • Harper, J.M., Thiru, S., Lockwood, C.M. and Cooke, A. Myeloperoxidase autoantibodies distinguish vasculitis mediated by anti-neutrophil cytoplasm antibodies from immune complex disease in MRL/Mp-lpr/lpr mice: a spontaneous model for human microscopic angiitis. Eur. J. Immunol. 1998, 28: 2217-26.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2217-2226
    • Harper, J.M.1    Thiru, S.2    Lockwood, C.M.3    Cooke, A.4
  • 15
    • 0013591239 scopus 로고
    • Degranulation of polymorphonuclear leucocytes following phagocytosis of microorganisms
    • Hirsch, J.G. and Cohn, Z.A. Degranulation of polymorphonuclear leucocytes following phagocytosis of microorganisms. J. Exp. Med. 1960, 112: 1005-14.
    • (1960) J. Exp. Med. , vol.112 , pp. 1005-1014
    • Hirsch, J.G.1    Cohn, Z.A.2
  • 16
    • 0020513594 scopus 로고
    • Polymorphic expression of a neutrophil differentiation antigen revealed by monoclonal antibody 7/4
    • Hirsch, S. and Gordon, S. Polymorphic expression of a neutrophil differentiation antigen revealed by monoclonal antibody 7/4. Immunogenetics 1983, 18: 229-39.
    • (1983) Immunogenetics , vol.18 , pp. 229-239
    • Hirsch, S.1    Gordon, S.2
  • 17
    • 0016840812 scopus 로고
    • Subcellular distribution of nitroblue tetrazolium redutase (NBT-R) in human polymorphonuclear leukocytes (PMN)
    • Baehner, R.L. Subcellular distribution of nitroblue tetrazolium redutase (NBT-R) in human polymorphonuclear leukocytes (PMN). J. Lab. Clin. Med. 1975, 86: 785-92.
    • (1975) J. Lab. Clin. Med. , vol.86 , pp. 785-792
    • Baehner, R.L.1
  • 18
    • 0017159513 scopus 로고
    • The biochemical basis of nitroblue tetrazolium reduction in normal human and chronic granulomatous disease polymorphonuclear leukocytes
    • Baehner, R.L., Boxer, L.A. and Davis, J. The biochemical basis of nitroblue tetrazolium reduction in normal human and chronic granulomatous disease polymorphonuclear leukocytes. Blood 1976, 48: 309-13.
    • (1976) Blood , vol.48 , pp. 309-313
    • Baehner, R.L.1    Boxer, L.A.2    Davis, J.3
  • 19
    • 0025782806 scopus 로고
    • A highly selected panel of anti-CD4 antibodies fails to induce anti-idiotypic antisera mediating human immunodeficiency virus neutralization
    • Healey, D.G., Dianda, L., Schroeder, K., Truneh, A., Sattentau, Q.J. and Beverley, P.C.L. A highly selected panel of anti-CD4 antibodies fails to induce anti-idiotypic antisera mediating human immunodeficiency virus neutralization. Eur. J. Immunol. 1991, 21: 1491-8.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 1491-1498
    • Healey, D.G.1    Dianda, L.2    Schroeder, K.3    Truneh, A.4    Sattentau, Q.J.5    Beverley, P.C.L.6
  • 20
  • 21
    • 0024376479 scopus 로고
    • Transformation of neutrophils as indicator of irreversibility of hemorrhagic shock
    • Barroso-Aranda, J. and Schmid-Schönbein, G.W. Transformation of neutrophils as indicator of irreversibility of hemorrhagic shock. Am. J. Physiol. 1989, 257: H846-52.
    • (1989) Am. J. Physiol. , vol.257
    • Barroso-Aranda, J.1    Schmid-Schönbein, G.W.2
  • 22
    • 0024351649 scopus 로고
    • Function and regulation of the neutrophil MEL-14 antigen in vivo: Comparison with LFA-1 and MAC-1
    • Jutila, M.A., Rott, L., Berg, E.L. and Butcher, E.C. Function and regulation of the neutrophil MEL-14 antigen in vivo: comparison with LFA-1 and MAC-1. J. Immunol. 1989, 143: 3318-24.
    • (1989) J. Immunol. , vol.143 , pp. 3318-3324
    • Jutila, M.A.1    Rott, L.2    Berg, E.L.3    Butcher, E.C.4
  • 23
    • 0027174208 scopus 로고
    • Control of exocytosis in early neutrophil activation
    • Sengelov, H., Kjeldsen, L. and Borregaard, N. Control of exocytosis in early neutrophil activation. J. Immunol. 1993, 150: 1535-43.
    • (1993) J. Immunol. , vol.150 , pp. 1535-1543
    • Sengelov, H.1    Kjeldsen, L.2    Borregaard, N.3
  • 24
    • 0027955338 scopus 로고
    • Identification of NGAL as a novel matrix protein of specific granules in human neutrophils
    • Kjeldsen, L., Bainton, D.F., Sengelov, H. and Borregaard, N. Identification of NGAL as a novel matrix protein of specific granules in human neutrophils. Blood 1994, 83: 799-807.
    • (1994) Blood , vol.83 , pp. 799-807
    • Kjeldsen, L.1    Bainton, D.F.2    Sengelov, H.3    Borregaard, N.4
  • 25
    • 0016206238 scopus 로고
    • Biochemical and morphological characteristics of azurophil and specific granules of human neutrophilic polymorphonuclear leukocytes
    • Bretz, U. and Baggiolini, M. Biochemical and morphological characteristics of azurophil and specific granules of human neutrophilic polymorphonuclear leukocytes. J. Cell Biol. 1974, 63: 251-69.
    • (1974) J. Cell Biol. , vol.63 , pp. 251-269
    • Bretz, U.1    Baggiolini, M.2
  • 26
    • 0014292067 scopus 로고
    • MPO-halide-hydrogen peroxide antibacterial system
    • Klebanoff, S.J. MPO-halide-hydrogen peroxide antibacterial system. J. Bacteriol. 1968, 95: 2131-2138.
    • (1968) J. Bacteriol. , vol.95 , pp. 2131-2138
    • Klebanoff, S.J.1
  • 27
    • 14844353173 scopus 로고
    • Mobilization of granules and secretary vesicles during in vivo exudation of human neutrophils
    • Sengelov, H., Follin, O., Kjeldsen, L., Lollike, K., Dahlgren, C. and Borregaard, N. Mobilization of granules and secretary vesicles during in vivo exudation of human neutrophils. J. Immunol. 1995, 154: 4157-65.
    • (1995) J. Immunol. , vol.154 , pp. 4157-4165
    • Sengelov, H.1    Follin, O.2    Kjeldsen, L.3    Lollike, K.4    Dahlgren, C.5    Borregaard, N.6
  • 28
    • 0027532596 scopus 로고
    • In situ production of TNF-alpha, IL-1 beta and IL-2R in ANCA-positive glomerulonephritis
    • Noronha, I.L., Kruger, C., Andrassy, K., Ritz, E. and Waldherr, R. In situ production of TNF-alpha, IL-1 beta and IL-2R in ANCA-positive glomerulonephritis. Kid. Int. 1993, 43: 682-92.
    • (1993) Kid. Int. , vol.43 , pp. 682-692
    • Noronha, I.L.1    Kruger, C.2    Andrassy, K.3    Ritz, E.4    Waldherr, R.5
  • 29
    • 0025304016 scopus 로고
    • Cytokines and endothelial cell biology
    • Pober, J.S. and Cotran, R.S. Cytokines and endothelial cell biology. Physiol. Rev. 1990, 70: 427-51.
    • (1990) Physiol. Rev. , vol.70 , pp. 427-451
    • Pober, J.S.1    Cotran, R.S.2
  • 30
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
    • Springer, T.A. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 1994, 76: 301-14.
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, T.A.1
  • 31
    • 0025836764 scopus 로고
    • Involvement of the CD11b/CD18 integrin, but not of the endothelial cell adhesion molecules ELAM-1 and ICAM-1 in tumour necrosis factor-α-induced neutrophil toxicity
    • Von Asmuth, E.J.U., Van der Linden, C.J., Leeuwenberg, J.F.M. and Buurman, W.A. Involvement of the CD11b/CD18 integrin, but not of the endothelial cell adhesion molecules ELAM-1 and ICAM-1 in tumour necrosis factor-α-induced neutrophil toxicity. J. Immunol. 1991, 147: 3869-75.
    • (1991) J. Immunol. , vol.147 , pp. 3869-3875
    • Von Asmuth, E.J.U.1    Van Der Linden, C.J.2    Leeuwenberg, J.F.M.3    Buurman, W.A.4
  • 33
    • 0343586179 scopus 로고
    • Intrarenal injection of lipopolysaccharide in myeloperoxidase immunized Brown Norway rats
    • Heeringa, P., Klok, P.A., Huitema, M.G., Foucher, P. and Kallenberg, C.G.M. Intrarenal injection of lipopolysaccharide in myeloperoxidase immunized Brown Norway rats. Clin. Exp. Immunol. 1995, 101 (Suppl. 1): 53.
    • (1995) Clin. Exp. Immunol. , vol.101 , Issue.SUPPL. 1 , pp. 53
    • Heeringa, P.1    Klok, P.A.2    Huitema, M.G.3    Foucher, P.4    Kallenberg, C.G.M.5
  • 34
    • 0029092391 scopus 로고
    • Antineutrophil cytoplasm antibodies and anti-glomerular basement membrane antibodies: Two coexisting distinct autoreactivities detectable in patients with rapidly progressive glomerulonephritis
    • Short, A.K., Fsnault, V.L.M. and Lockwood, C.M. Antineutrophil cytoplasm antibodies and anti-glomerular basement membrane antibodies: two coexisting distinct autoreactivities detectable in patients with rapidly progressive glomerulonephritis. Am. J. Kid. Dis. 1995, 26: 439-45.
    • (1995) Am. J. Kid. Dis. , vol.26 , pp. 439-445
    • Short, A.K.1    Fsnault, V.L.M.2    Lockwood, C.M.3
  • 35
    • 0012012494 scopus 로고
    • Aggravation of rat Masugi nephritis by heterologous anti-rat myeloperoxidase (MPO) antibody
    • Kobyashi, K., Shibata, T. and Sugisaki, T. Aggravation of rat Masugi nephritis by heterologous anti-rat myeloperoxidase (MPO) antibody. Clin. Exp. Immunol. 1993, 93 (Suppl. 1): 20.
    • (1993) Clin. Exp. Immunol. , vol.93 , Issue.SUPPL. 1 , pp. 20
    • Kobyashi, K.1    Shibata, T.2    Sugisaki, T.3
  • 36
    • 0001895168 scopus 로고
    • Genetic basis of vasculitis in lupus mice
    • Tanabe, T. (Ed.) Sapporo: Hokkaido University Press
    • Nose, M. Genetic basis of vasculitis in lupus mice. In: Tanabe, T. (Ed.) Intractable Vasculitis Syndromes. Sapporo: Hokkaido University Press, 1993: pp. 145-53.
    • (1993) Intractable Vasculitis Syndromes , pp. 145-153
    • Nose, M.1
  • 37
    • 0023429945 scopus 로고
    • Sequential study of vasculitis in MRL mice
    • Hewicker, M. and Trautwein, G. Sequential study of vasculitis in MRL mice. Lab. Anim. 1987, 21: 335-41.
    • (1987) Lab. Anim. , vol.21 , pp. 335-341
    • Hewicker, M.1    Trautwein, G.2
  • 38
    • 0023429087 scopus 로고
    • Reactive lymphocytes in lacrimal gland and vasculitic lesions of autoimmune MRL/ lpr mice express L3T4
    • Jabs, D.A. and Prendergast, R.A. Reactive lymphocytes in lacrimal gland and vasculitic lesions of autoimmune MRL/ lpr mice express L3T4. J. Exp. Med. 1987, 166: 1198-1203.
    • (1987) J. Exp. Med. , vol.166 , pp. 1198-1203
    • Jabs, D.A.1    Prendergast, R.A.2
  • 39
    • 0023936719 scopus 로고
    • Features of renal vasculitis in autoimmune MRL-lpr/lpr mice: Phenotypes and functional properties of infiltrating cells
    • Tarkowski, A., Jonsson, R., Sanchez, R., Klareskog, L. and Koopman, W.J. Features of renal vasculitis in autoimmune MRL-lpr/lpr mice: phenotypes and functional properties of infiltrating cells. Clin. Exp. Immunol. 1988, 72: 91-97.
    • (1988) Clin. Exp. Immunol. , vol.72 , pp. 91-97
    • Tarkowski, A.1    Jonsson, R.2    Sanchez, R.3    Klareskog, L.4    Koopman, W.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.