The plant alkaloid usambarensine intercalates into DNA and induces apoptosis in human HL60 leukemia cells

Anticancer Research

Volumn 19, Issue 6 B, 1999, Pages 5245-5250

  Dassonneville, Laurent ^a   Wattez, Nicole ^a   Mahieu, Christine ^a   Colson, Pierre ^b   Houssier, Claude ^b   Frederich, Michel ^c   Tits, Monique ^c   Angenot, Luc ^c   Bailly, Christian ^a  

^a INSERM   (France)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Apoptosis; DNA intercalation; Plant alkaloid; Usambarensine

Indexed keywords

ALKALOID; ANTINEOPLASTIC AGENT; CASPASE; CRYPTOLEPINE; DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); MATADINE; UNCLASSIFIED DRUG; USAMBARENSINE;

ABSORPTION SPECTROSCOPY; APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL STRAIN HL 60; CIRCULAR DICHROISM; CONTROLLED STUDY; DNA DEGRADATION; DRUG CYTOTOXICITY; DRUG DNA INTERACTION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INTERCALATION COMPLEX; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ALKALOIDS; CIRCULAR DICHROISM; DNA; DNA TOPOISOMERASES, TYPE I; ENZYME INHIBITORS; HL-60 CELLS; HUMANS; INDOLES; INTERCALATING AGENTS; PLANTS;

EID: 0033377437     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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