Increased CD4+CD16+ and CD4+CD56+ T cell subsets in Behcet's disease

Rheumatology International

Volumn 19, Issue 1-2, 1999, Pages 23-26

  Eksioglu Demiralp, E ^a   Direskeneli, H ^b   Ergun, T ^b   Fresko, I ^c   Akoglu, T ^b  

^a Kosuyolu Cad   (Turkey)

^b Istanbul School of Medicine   (Turkey)

^c ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Behcet's disease; CD16+CD56+; Cytotoxic T cells

Indexed keywords

CD4 ANTIGEN; CD56 ANTIGEN;

ADULT; ARTICLE; BEHCET DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; MALE; NATURAL KILLER CELL; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

EID: 0033376982     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002960050094     Document Type: Article

References (20)

1. Yazici H, Yurdakul S, Hamuryudan V (1999) Behçet's syndrome. Curr Opinion in Rheumatol 11:53-57
2. Emmi L, Salvati G, Brugnola F, Marchiono T (1995) Immunopathological aspects of Behçet's disease (editorial). Clin Exp Rheumatol 13:687-691
3. Direskeneli H, Eksioglu-Demiralp E, Akoglu T (1999) Etiopathogenesis of Behçet's syndrome: recent developments and current controversies. Marmara Med J 12: 2:101-106
4. Kahan A, Hamzaoui K, Ayed K (1991) Abnormalities of T lymphocyte subsets in Behçet's disease demonstrated with anti-CD45RA and anti-CD29 monoclonal antibodies. J Rheumatol 19:742-746
5. Hamzaoui K, Hamzaoui A, Hentati A, Kahan A, Ayed K, Chabbou A, Hamida MB, Hamza M (1994) Phenotype and functional profile of T cells expressing γδ receptor from patients with active Behçet's disease. J Rheumatol 21:2301-2306
6. Hamzaoui K, Ayed K, Hamza M, Touraine JL (1988) Natural killer cells in Behçet's disease. Clin Exp Immunol 71:126-131
7. Kaneko F, Takahashi Y, Muramatsu R, Adachi K, Miura Y, Nakane A, Minagawa T (1985) Natural killer cell numbers and function in peripheral lymphoid cells in Behçet's Disease. Br J Dermatol 113:313-318
8. Levitz MS, Mathews HL, Murphy JW (1995) Direct anti-microbial activity of T cells. Immunology Today 16:387-391
9. Vergelli M, Le H, van Noort JM, Dhib-Jalbut S, McFarland H, Martin R (1996) A novel population of CD4 + CD56 + myelin-reactive T cells lyses target cells expressing CD56/neural cell adhesion molecule. J Immunol 157:679-688
10. Schmidt-Wolf IGH, Lefterova P, Jhonston V, Huhn D, Blume KG, Negrin RS (1994) Propagation of large number of T cells with natural killer cell markers. Br J Haematol 87:453-458
11. Barnaba U, Franco A, Paroli M, Benvenuto R, Ferrarini M (1994). Selective expansion of cytotoxic T lymphocytes with a CD4+CD56+ surface phenotype and a T helper type 1 profile of cytokine secretion in the liver of patients chronically infected with hepatitis B virus. J Immunol 152:3074-3087
12. Dummer R, Potoczna N, Haffner AC, Zimmermann DR, Gilardi S, Burg G (1996) A primary cutaneous non-T, non-B CD4+CD56+ lymphoma. Arch Dermatol 132:550-553
13. International study group for Behçet's disease (1990) Criteria for diagnosis of Behçet's disease. Lancet 335:1078-1080
14. Schlossman SF, Boumsell L, Gilk W (eds) (1995) Leucocyte typing V, white cell differentiation antigens, Vol. 1, Oxford University Press
15. Lanier LL, Lee AM, Civin CI, Loken MR, Phillips JH (1986) The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J Immunol 136:4480-4486
16. Direskeneli H, Eksioglu-Demiralp E, Kibaróglu A, Yavuz S, Ergun T, Akoglu T (1999) Oligoclonal T cell expansions in patients with Behçet's disease. Clin Exp Immunol 117:166-170
17. Gül A, Esin S, Dilsen N, Koniçe M, Wigzell H, Biberfeld P (1995) Immunohistology of skin pathergy reaction in Behçet's disease. British J Dermatology 132:901-907
18. Akoglu TF, Direskeneli H, Yazici H et al (1990) TNFα, soluble IL2, and soluble CD8 in Behçet's disease. J Rheumatol 17:1107-1108
19. Mege JL, Dilsen N, Sanguedolce V et al (1993) Overproduction of monocyte-derived TNF-α, IL6, IL8, and increased neutrophil superoxide generation in Behçet's disease. A comparative study with familial Mediterranean fever and healthy subjects. J Rheumatol 20:1544-1549
20. Sugi-Ikai N, Nakazawa M, Nakamura S et al (1998) Increased frequencies of interleukin-2 and interferon-γ-producing T cells in patients with active Behçet's disease. Invest Ophthalmol Vis Sci 39:996-1004