Effect of the inhibition of xanthine oxidase in hepatic cells lipid peroxidation

Medical Science Research

Volumn 27, Issue 12, 1999, Pages 829-830

  Rhoden, E L ^a   Pereira Lima, L ^b   Mauri, M ^c   Lucas, M L ^b   Rhoden, C R ^c   Bello Klein, A ^b  

^a Department of A Surgery ^*  (Brazil)

^b UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGRE   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Allopurinol; Ischaemia reperfusion; Lipid peroxidation; Liver; Xanthine oxidase

Indexed keywords

ALLOPURINOL; MALONALDEHYDE; OXYGEN RADICAL; XANTHINE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; ENZYME INHIBITION; ISCHEMIA; LIPID LIVER LEVEL; LIPID PEROXIDATION; LIVER ISCHEMIA; NONHUMAN; RAT; REPERFUSION;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0033375037     PISSN: 02698951     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Bulkey GB. The role of oxygen free radicals in human disease processes. Surgery 1983; 94:407-411.
2. Müller MJ, Vollmar B, Friedl HP, Menger MD. Xanthine oxidase and Superoxide radicals in portal triad crossclamping-induced microvascular reperfusion injury of the liver. Free Radie Biol Med 1996: 21:189-197.
3. Stein HJ, Oosthuizen MMJ, Hinder RA. Lamprechts H. Effect of verapamil on hepatic ischemia/reperfusion injury. Am J Surg 1993: 165:96-100.
4. Palier MS, Hoidal JR, Ferris T. Oxygen free radicals in ischémie acute renal failure in the rat. J Clin Invest 1984; 74:1156-1164.
5. Jassem W, Roake J. The molecular and cellular basis of reperfusion injury following organ transplantation. Transplant Rev 1998; 12:14-33.
6. Nunes FA, Kumar C, Chance B, Brass CA. Chemiluminescent measurement of increased free radical formation after ischaemiareperfusion. Mechanisms of free radical formation in the liver. Dig Dis Sci1995; 40:1045-1053.
7. Buege JA, Aust D. Microsomal lipid peroxidation. Meth Enzymol 1978:52:302-309.
8. Gonzalez-Flecha B, Llesuy S, Boveris A. Hydroperoxide-initiated chemiluminescence: an assay for oxidative stress in biopsies of heart, liver and muscle. Free Radie Biol Med 1991: 10:93-100.
9. Marubayashi S, Dohi K, Yamada K, Kawasaki T. Role of conversion of xanthine dehydrogenase to oxidase in ischemia rat liver cell injury. Surgery 1991; 10:537-543.
10. Matsumoto F, Sakai H, Yamaguchi M, Nakano H, Matsumiya A, Kumada K, et al. Allopurinol reduced hepatic ischemia-reperfusion injury exacerbated by inhalation of high-concentration oxygen in rats. EurSurg Res 1997; 29:429-437.
11. Zager RA, Gmur DJ. Effects of xanthine oxidase inhibition on ischémie acute renal failure. Am J Physiol 1989: 257:953-958.
12. Karwinski W, Bolann B, Ulvik R, Farstad, Soreide O. Normothermic liver ischemia in rats: xanthine oxidase is not the main source of oxygen free radicals. Res Exp Med 1993; 193:275-283.
13. Galat JA, Robinson AV, Rhodes RS. Postischemic renal dysfunction: the limited role of xanthine oxidase-generated oxygen free radicals. J Surg Res 1990; 49:488-92.
14. Cighetti G, Debiasi S, Paroni R. No documentable role of xanthine oxidase in the pathogenesis of hepatic in vivo ischaemia-reperfusion injury. Pharmacol Res 1994; 30:243-251.