T-cell antigen specificity in humans following stimulation with Porphyromonas gingivalis

Archives of Oral Biology

Volumn 44, Issue 12, 1999, Pages 1045-1053

  Nakajima, Takako ^a   Yamazaki, Kazuhisa ^a   Cullinan, Mary P ^a   Gemmell, Erica ^a   Seymour, Gregory J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Clonotype; Cytokine; P. gingivalis; Periodonititis; SSCP; TCR

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 4; LYMPHOCYTE ANTIGEN RECEPTOR; MESSENGER RNA;

ANTIGEN SPECIFICITY; ARTICLE; BACTERIAL INFECTION; CELL CLONE; CELL CULTURE; CONTROLLED STUDY; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; GINGIVITIS; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MONOCYTE; MONONUCLEAR CELL; PATHOLOGY; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE RECEPTOR GENE;

BACTEROIDACEAE INFECTIONS; CELLS, CULTURED; CLONE CELLS; CYTOKINES; GENE EXPRESSION REGULATION; GENES, T-CELL RECEPTOR BETA; GINGIVITIS; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; INTERFERON TYPE II; INTERLEUKIN-13; LEUKOCYTES, MONONUCLEAR; PERIODONTITIS; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PORPHYROMONAS GINGIVALIS; RECEPTORS, ANTIGEN, T-CELL; RNA, MESSENGER; T-LYMPHOCYTES;

EID: 0033373759     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9969(99)00094-1     Document Type: Article

References (28)

1. Bird P.S., Seymour G.J. Production of monoclonal antibodies that recognize specific and cross-reactive antigens of Fusobacterium nucleatum. Infect. Immun. 55:1987;771-777.
2. Boitel B., Ermonval M., Panina-Bordignon P., Mariuzza R.A., Lanzavecchia A., Acuto O. Preferential Vβ gene usage and lack of junctional sequence conservation among human T cell receptors specific for a tetanus toxin-derived peptide: Evidence for a dominant role of a germline-encoded V region in antigen/major histocompatibility complex recognition. J. Exp. Med. 175:1992;765-777.
3. Boyd J., McBride B.C. Fractionation of haemagglutinating and bacterial binding adhesions of Bacteroides gingivalis. Infect. Immun. 45:1984;403-409.
4. Choi Y., Kotzin B., Herron L., Callahan J., Marrack P., Kappler J. Interaction of Staphylococcus aureus toxin "Superantigens" with human T cells. Proc. Natl. Acad. Sci., USA. 86:1989;8941-8945.
5. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analyt. Biochem. 162:1987;156-159.
6. Davis M.M., Bjorkman P.J. T-cell antigen receptor genes and T-cell recognition. Nature. 334:1988;395-402.
7. Gemmell E., Seymour G.J. Cytokine profiles of cells extracted from humans with periodontal diseases. J. Dent. Res. 77:1998;16-26.
8. Gemmell E., Kjeldsen M., Yamazaki K., Nakajima T., Aldred M.J., Seymour G.J. Cytokine profiles of Porphyromonas gingivalis-reactive T lymphocyte lines and clones derived from P. gingivalis-infected subjects. Oral Diseases. 1:1995;139-146.
9. Gemmell E., Marshall R.I., Seymour G.J. Cytokines and prostaglandins in immune homeostasis and tissue destruction in periodontal disease. Periodontology. 2000:(14):1997;112-143.
10. Gemmell E., Woodford V., Seymour G.J. Characterization of T lymphocyte clones derived from Porphyromonas gingivalis infected subjects. J. Periodont. Res. 31:1996;47-56.
11. Genco R.J., Slots J. Host responses in periodontal disease. J. Dent. Res. 63:1984;441-451.
12. Kawai T., Shimauchi H., Eastcott J.W., Smith D.J., Taubman M.A. Antigen direction of specific T-cell clones into gingival tissues. Immunology. 93:1998;11-19.
13. Ling P., Gately M.K., Gubler U. Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity. J. Immunol. 154:1995;116-127.
14. Mahanonda R., Seymour G.J., Powell L.W., Good M.F., Halliday J.W. Effect of initial treatment of chronic inflammatory periodontal disease on the frequency of peripheral blood T-lymphocytes specific to periodontopathic bacteria. Oral Microbiol. Immunol. 6:1991;221-227.
15. Manhart S.S., Reinhardt R.A., Payne J.B., Seymour G.J., Gemmell E., Dyer J.K., Petro T.M. Gingival cell IL-2 and IL-4 in early-onset periodontitis. J. Periodontol. 65:1994;807-813.
16. Mayrand D., Holt S.C. Biology of asaccharolytic Bacteroides species. Microbiol. Rev. 2:1988;134-152.
17. Nakajima T., Yamazaki K., Sakurai K., Gemmell E., Seymour G.J., Hara K. Detection of clonotypic changes of T cells after stimulation with Porphyromonas gingivalis. Oral Microbiol. Immunol. 13:1998;238-245.
18. O'Garra A. Peptide regulatory factors. Interleukins and the immune system 2. Lancet. 1:1989;1003-1005.
19. Okuda K., Takazoe I. The role of Bacteroides gingivalis in periodontal disease. Adv. Dent. Res. 2:1988;260-268.
20. Romagnani S. Lymphokine production by human T cells in disease states. Annu. Rev. Immunol. 12:1994;227-258.
21. Seymour G.J. Possible mechanisms involved in the immunoregulation of chronic inflammatory periodontal disease. J. Dent. Res. 66:1987;2-9.
22. Seymour G.J., Gemmell E., Reinhardt R.A., Eastcott J., Taubman M.A. Immunopathogenesis of chronic inflammatory periodontal disease: cellular and molecular mechanisms. J. Periodont. Res. 28:1993;478-486.
23. Seymour G.J., Gemmell E., Kjeldsen M., Yamazaki K., Nakajima T., Hara K. Cellular immunity and hypersensitivity as components of periodontal destruction. Oral Diseases. 2:1996;96-101.
24. Wassenaar A., Reinhardus C., Thepen T., Abraham-Injupin L., Kievits F. Cloning, characterization, and antigen specificity of T-lymphocyte subsets extracted from gingival tissue of chronic adult periodontitis patients. Infect. Immun. 63:1995;2147-2153.
25. Yamamoto K., Sakoda H., Nakajima T., Kato T., Okubo M., Dohi M., Mizushima Y., Ito K., Nishioka K. Accumulation of multiple T cell clonotypes in the synovial lesions of patients with rheumatoid arthritis revealed by a novel clonality analysis. Int. Immunol. 4:1992;1219-1223.
26. Yamazaki K., Nakajima T., Gemmell E., Polak B., Seymour G.J., Hara K. IL-4 and IL-6 producing cells in human periodontal disease tissue. J. Oral Pathol. Med. 23:1994;347-353.
27. Yamazaki K., Nakajima T., Gemmell E., Kjeldsen M., Seymour G.J., Hara K. Biased expression of T cell receptor Vβ genes in periodontitis patients. Clin. Exp. Immunol. 106:1996;329-335.
28. Yamazaki K., Nakajima T., Kubota Y., Gemmell E., Seymour G.J., Hara K. Cytokine messenger RNA expression in chronic inflammatory periodontal disease. Oral Microbiol. Immunol. 12:1997;281-287.