The COCH gene: A frequent cause of hearing impairment and vestibular dysfunction?

British Journal of Audiology

Volumn 33, Issue 5, 1999, Pages 297-302

  Fransen, E ^a   Van Camp, Guy ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

COCH; DFNA9; Hearing impairment; Meniere's disease; Vertigo; Vestibular dysfunction

Indexed keywords

GLYCOSAMINOGLYCAN;

AUTOSOMAL DOMINANT INHERITANCE; CONFERENCE PAPER; GENE ISOLATION; HEARING IMPAIRMENT; HISTOPATHOLOGY; HUMAN; INNER EAR; PATHOLOGY; PERCEPTION DEAFNESS; PRIORITY JOURNAL; VESTIBULAR DISORDER;

EID: 0033372112     PISSN: 03005364     EISSN: None     Source Type: Journal    
DOI: 10.3109/03005369909090113     Document Type: Conference Paper

References (14)

1. Arnvig J. Vestibular function in deafness and severe hard of hearing. Acta Otolaryngol 1955; 45: 283-8.
2. Avraham KB, Hasson T, Steel KP, Kingsley DM, Russell LB, Mooseker MS et al. The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells. Nat Genet 1995; 11: 369-75.
3. Brown SD, Steel KP. Genetic deafness - progress with mouse models. Hum Mol Genet 1994; 3: 1453-6.
4. de Kok Y, Bom SJH, Brunt TM, Kemperman MH, van Beusekom E, van der Velde-Visser SD et al. A Pro51Ser mutation in the COCH gene is associated with late-onset autosomal dominant progressive sensorineural hearing loss with vestibular defects. Hum Mol Genet 1999; 8: 361-6.
5. Dohlman G. Mechanism of the Ménière attack. ORL 1980; 42: 10-19.
6. Fransen E, Verstreken M, Verhagen WIM, Wuyts FL, Huygen PLM, D'Haese P. High prevalence of symptoms of Ménière's disease in two families with a mutation in the COCH gene. Hum Mol Genet 1999; 8: 1425-9.
7. Khetarpal U. Autosomal dominant sensorineural hearing loss. Further temporal bone findings. Arch Otolaryngol Head Neck Surg 1993; 119: 106-8.
8. Khetarpal U, Schuknecht HF, Gacek RR, Holmes LB. Autosomal dominant sensorineural hearing loss. Pedigrees, audiologic findings, and temporal bone findings in two kindreds. Arch Otolaryngol Head Neck Surg 1991; 117: 1032-42.
9. Manolis EN, Yandavi N, Nadol JB, Eavey RD, McKenna M, Rosenbaum S et al. A gene for non-syndromic autosomal dominant progressive postlingual sensorineural hearing loss maps to chromosome 14q12-13. Hum Mol Genet 1996; 5: 1047-50.
10. Robertson NG, Khetarpal U, Gutierrez-Espeleta GA, Bieber FR, Morton CC. Isolation of novel and known genes from a human fetal cochlear cDNA library using substractive hybridization and differential screening. Genomics 1994; 23: 42-50.
11. Robertson NG, Skvorak AB, Yin Y, Weremowicz S, Johnson KR, Kovatch KA et al. Mapping and characterization of a novel cochleargene in human and in mouse: a positional candidate gene for a deafness disorder, DFNA9. Genomics 1997; 46: 345-54.
12. Robertson NG, Lu L, Heller S, Merchant SN, Eavey RD, McKenna M et al. Mutations in a novel cochlear gene cause DFNA9, a human non-syndromic sensorineural deafness with vestibular dysfunction. Nature Genet 1998; 20: 299-303.
13. Sandberg L, Terkildsen K. Caloric tests in deaf children. Arch Otolaryngol 1965; 81: 352-4.
14. Van de Heyning PH, Wuyts FL, Claes J, Koekelkoren E, Van Laer C, Valcke H. Definition, classification and reporting of Ménière's disease and its symptoms. Acta Otolaryngol (Suppl.) 1997; 526: 5-9.